Search Results - "MATEOS, I"
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Co‐immobilized Phosphorylated Cofactors and Enzymes as Self‐Sufficient Heterogeneous Biocatalysts for Chemical Processes
Published in Angewandte Chemie International Edition (16-01-2017)“…Enzyme cofactors play a major role in biocatalysis, as many enzymes require them to catalyze highly valuable reactions in organic synthesis. However, the…”
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2
Dual Valorization of Lignin as a Versatile and Renewable Matrix for Enzyme Immobilization and (Flow) Bioprocess Engineering
Published in ChemSusChem (09-08-2021)“…Lignin has emerged as an attractive alternative in the search for more eco‐friendly and less costly materials for enzyme immobilization. In this work, the…”
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3
Towards Greener and More Cost-efficient Biosynthesis of Pharmaceuticals and Fragrance Molecules
Published in Chimia (24-04-2024)“…Enzymes are natural catalysts which are gaining momentum in chemical synthesis due to their exquisiteselectivity and their biodegradability. However, the…”
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Halomonas elongata: a microbial source of highly stable enzymes for applied biotechnology
Published in Applied microbiology and biotechnology (01-05-2023)“…Extremophilic microorganisms, which are resistant to extreme levels of temperature, salinity, pH, etc., have become popular tools for biotechnological…”
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Sustainable Flow‐Synthesis of (Bulky) Nucleoside Drugs by a Novel and Highly Stable Nucleoside Phosphorylase Immobilized on Reusable Supports
Published in ChemSusChem (10-01-2022)“…The continuous synthesis of valuable nucleoside drugs was achieved in up to 99 % conversion by using a novel halotolerant purine nucleoside phosphorylase from…”
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Asymmetric Reduction of Prochiral Ketones by Using Self‐Sufficient Heterogeneous Biocatalysts Based on NADPH‐Dependent Ketoreductases
Published in Chemistry : a European journal (27-11-2017)“…The development of cell‐free and self‐sufficient biocatalytic systems represents an emerging approach to address more complex synthetic schemes under…”
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Biocatalytic Synthesis of l‐Pipecolic Acid by a Lysine Cyclodeaminase: Batch and Flow Reactors
Published in ChemCatChem (24-06-2024)“…l‐Pipecolic Acid (l‐PA) is a valuable building block for the synthesis of pharmaceuticals such as anesthetics and immunosuppressants. Thus, more efficient and…”
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Design of the Enzyme–Carrier Interface to Overcome the O2 and NADH Mass Transfer Limitations of an Immobilized Flavin Oxidase
Published in ACS applied materials & interfaces (16-12-2020)“…Understanding how the immobilization of enzymes on solid carriers affects their performance is paramount for the design of highly efficient heterogeneous…”
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Beyond the Required LISA Free-Fall Performance: New LISA Pathfinder Results down to 20 μHz
Published in Physical review letters (05-02-2018)“…In the months since the publication of the first results, the noise performance of LISA Pathfinder has improved because of reduced Brownian noise due to the…”
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Chemoenzymatic Approaches to the Synthesis of the Calcimimetic Agent Cinacalcet Employing Transaminases and Ketoreductases
Published in Advanced synthesis & catalysis (05-06-2018)“…Several chemoenzymatic routes have been explored for the preparation of cinacalcet, a calcimimetic agent. Transaminases (TAs) and ketoreductases (KREDs) turned…”
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11
Single-Particle Kinetics of Immobilized Enzymes by Harnessing the Autofluorescence of Co-Immobilized Cofactors
Published in Methods in molecular biology (Clifton, N.J.) (01-01-2020)“…The co-immobilized enzymes and cofactors onto porous microparticles work as self-sufficient heterogeneous biocatalysts whose catalytic activity can be easily…”
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12
Local environment in biomolecular condensates modulates enzymatic activity across length scales
Published in Nature communications (18-04-2024)“…The mechanisms that underlie the regulation of enzymatic reactions by biomolecular condensates and how they scale with compartment size remain poorly…”
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13
Fusion of Formate Dehydrogenase and Alanine Dehydrogenase as an Amino Donor Regenerating System Coupled to Transaminases
Published in Chembiochem : a European journal of chemical biology (04-11-2022)“…Fusion enzymes are attractive tools for facilitating the assembly of biocatalytic cascades for chemical synthesis. This approach can offer great advantages for…”
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14
Agarose vs. Methacrylate as Material Supports for Enzyme Immobilization and Continuous Processing
Published in Catalysts (01-07-2021)“…Enzyme immobilization has become a key strategy to improve the stability and recycling of biocatalysts, resulting in greener and more cost-efficient processes…”
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15
Spheroplasts preparation boosts the catalytic potential of a squalene-hopene cyclase
Published in Nature communications (21-10-2022)“…Squalene-hopene cyclases are a highly valuable and attractive class of membrane-bound enzymes as sustainable biotechnological tools to produce aromas and…”
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Self-Sufficient Flow-Biocatalysis by Coimmobilization of Pyridoxal 5′-Phosphate and ω‑Transaminases onto Porous Carriers
Published in ACS sustainable chemistry & engineering (01-10-2018)“…We expanded the application of self-sufficient heterogeneous biocatalysts containing coimmobilized ω-transaminases and pyridoxal 5′-phosphate (PLP) to…”
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Multifunctional antioxidant activity of polysaccharide fractions from the soybean byproduct okara
Published in Carbohydrate polymers (05-09-2010)“…An alcohol insoluble residue (AIR) from okara, a byproduct from soymilk, was mainly composed by indigestible carbohydrate (55.7%). After sequential extraction,…”
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18
Solid-Phase Assembly of Multienzyme Systems into Artificial Cellulosomes
Published in Bioconjugate chemistry (15-09-2021)“…We herein describe a bioinspired solid-phase assembly of a multienzyme system scaffolded on an artificial cellulosome. An alcohol dehydrogenase and an…”
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19
Modelling propofol pharmacodynamics using BIS‐guided anaesthesia
Published in Anaesthesia (01-11-2013)“…Summary Using Schnider's pharmacokinetic model, propofol pharmacodynamics were modelled during total intravenous anaesthesia. The method involved adjusting a…”
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Manufacturing of Protein-Based Biomaterials Coupling Cell-Free Protein Synthesis with Protein Immobilization
Published in Methods in molecular biology (Clifton, N.J.) (01-01-2020)“…Manufacturing of protein-based biomaterials is gaining momentum in biomedical applications. In this chapter, we describe the procedures to create a versatile…”
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