Search Results - "MATEO, Philippe"
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Real-Time Assessment of Myocardial Contractility Using Shear Wave Imaging
Published in Journal of the American College of Cardiology (28-06-2011)“…Objectives The goal of this study was to assess whether myocardial stiffness could be measured by shear wave imaging (SWI) and whether myocardial stiffness…”
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Modulation of cardiac cAMP signaling by AMPK and its adjustments in pressure overload-induced myocardial dysfunction in rat and mouse
Published in PloS one (21-09-2023)“…The beta-adrenergic system is a potent stimulus for enhancing cardiac output that may become deleterious when energy metabolism is compromised as in heart…”
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3
Down-regulation of OPA1 alters mouse mitochondrial morphology, PTP function, and cardiac adaptation to pressure overload
Published in Cardiovascular research (01-06-2012)“…The optic atrophy 1 (OPA1) protein is an essential protein involved in the fusion of the mitochondrial inner membrane. Despite its high level of expression,…”
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4
Resveratrol improves survival, hemodynamics and energetics in a rat model of hypertension leading to heart failure
Published in PloS one (18-10-2011)“…Heart failure (HF) is characterized by contractile dysfunction associated with altered energy metabolism. This study was aimed at determining whether…”
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Shear Wave Imaging of Passive Diastolic Myocardial Stiffness
Published in JACC. Cardiovascular imaging (01-09-2016)“…Abstract Objectives The aim of this study was to investigate the potential of shear wave imaging (SWI), a novel ultrasound-based technique, to noninvasively…”
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6
Activation of AMP kinase α1 subunit induces aortic vasorelaxation in mice
Published in The Journal of physiology (01-06-2007)“…Vasodilatation is a vital mechanism of systemic blood flow regulation that occurs during periods of increased energy demand. The AMP‐dependent protein kinase…”
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7
Control of cytoplasmic and nuclear protein kinase A by phosphodiesterases and phosphatases in cardiac myocytes
Published in Cardiovascular research (01-04-2014)“…The cAMP-dependent protein kinase (PKA) mediates β-adrenoceptor (β-AR) regulation of cardiac contraction and gene expression. Whereas PKA activity is well…”
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8
Epac stimulation induces rapid increases in connexin43 phosphorylation and function without preconditioning effect
Published in Pflügers Archiv (01-09-2010)“…It has been recently shown that β-adrenergic receptors are able to activate phospholipase C via the cyclic adenosine monophosphate-binding protein Epac. This…”
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Impaired voluntary running capacity of creatine kinase-deficient mice
Published in The Journal of physiology (15-06-2005)“…The creatine kinase system (CK) is important for energy delivery in skeletal and cardiac muscles. The two main isoforms of this enzyme, cytosolic MM-CK and…”
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AMP-Activated Protein Kinase α2 Deficiency Affects Cardiac Cardiolipin Homeostasis and Mitochondrial Function
Published in Diabetes (New York, N.Y.) (01-03-2007)“…AMP-Activated Protein Kinase α2 Deficiency Affects Cardiac Cardiolipin Homeostasis and Mitochondrial Function Yoni Athéa 1 2 3 , Benoît Viollet 4 5 6 7 ,…”
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Oxidative capacity of skeletal muscle in heart failure patients versus sedentary or active control subjects
Published in Journal of the American College of Cardiology (01-10-2001)“…OBJECTIVES We investigated the in situ properties of muscle mitochondria using the skinned fiber technique in patients with chronic heart failure (CHF) and…”
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12
Lebetin 2, a Snake Venom-Derived Natriuretic Peptide, Attenuates Acute Myocardial Ischemic Injury through the Modulation of Mitochondrial Permeability Transition Pore at the Time of Reperfusion
Published in PloS one (12-09-2016)“…Cardiac ischemia is one of the leading causes of death worldwide. It is now well established that natriuretic peptides can attenuate the development of…”
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13
Phosphorylation-dependent alteration in myofilament Ca2+ sensitivity but normal mitochondrial function in septic heart
Published in American journal of respiratory and critical care medicine (01-02-2001)“…The subcellular mechanisms responsible for myocardial depression during sepsis remain unclear. Recent data suggest a role for impaired energy generation and…”
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Potential impact of thermal effects during ultrasonic neurostimulation: retrospective numerical estimation of temperature elevation in seven rodent setups
Published in Physics in medicine & biology (09-01-2018)“…In the past decade, a handful but growing number of groups have reported worldwide successful low intensity focused ultrasound induced neurostimulation trials…”
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Coronary Flow Assessment Using 3-Dimensional Ultrafast Ultrasound Localization Microscopy
Published in JACC. Cardiovascular imaging (01-07-2022)“…BACKGROUNDDirect assessment of the coronary microcirculation has long been hampered by the limited spatial and temporal resolutions of cardiac imaging…”
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SIRT1 protects the heart from ER stress-induced cell death through eIF2α deacetylation
Published in Cell death and differentiation (01-02-2017)“…Over the past decade, endoplasmic reticulum (ER) stress has emerged as an important mechanism involved in the pathogenesis of cardiovascular diseases including…”
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Curved Toroidal Row Column Addressed Transducer for 3D Ultrafast Ultrasound Imaging
Published in IEEE transactions on medical imaging (01-09-2024)“…3D Imaging of the human heart at high frame rate is of major interest for various clinical applications. Electronic complexity and cost has prevented the…”
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31P NMR Detection of Subcellular Creatine Kinase Fluxes in the Perfused Rat Heart
Published in The Journal of biological chemistry (24-05-2002)“…The subcellular fluxes of exchange of ATP and phosphocreatine (PCr) between mitochondria, cytosol, and ATPases were assessed by 31P NMR spectroscopy to…”
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Cardiac Overexpression of PDE4B Blunts β-Adrenergic Response and Maladaptive Remodeling in Heart Failure
Published in Circulation (New York, N.Y.) (14-07-2020)“…BACKGROUND:The cyclic AMP (adenosine monophosphate; cAMP)-hydrolyzing protein PDE4B (phosphodiesterase 4B) is a key negative regulator of cardiac β-adrenergic…”
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Antihypertensive and endothelium-dependent vasodilator effects of aqueous extract of Cistus ladaniferus
Published in Biochemical and biophysical research communications (06-11-2009)“…Cistus ladaniferus L. (Cistaceae) is a medicinal plant originated from the Mediterranean region which exerts different pharmacological effects. In the present…”
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