Search Results - "MATECZUN, Alfred"
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Development and Use of Personalized Bacteriophage-Based Therapeutic Cocktails To Treat a Patient with a Disseminated Resistant Acinetobacter baumannii Infection
Published in Antimicrobial agents and chemotherapy (01-10-2017)“…Widespread antibiotic use in clinical medicine and the livestock industry has contributed to the global spread of multidrug-resistant (MDR) bacterial…”
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Comparison of three next-generation sequencing platforms for metagenomic sequencing and identification of pathogens in blood
Published in BMC genomics (04-02-2014)“…The introduction of benchtop sequencers has made adoption of whole genome sequencing possible for a broader community of researchers than ever before…”
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Genomic characterization of the Bacillus cereus sensu lato species: backdrop to the evolution of Bacillus anthracis
Published in Genome research (01-08-2012)“…The key genes required for Bacillus anthracis to cause anthrax have been acquired recently by horizontal gene transfer. To understand the genetic background…”
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In Vitro Analysis of Acetalated Dextran Microparticles as a Potent Delivery Platform for Vaccine Adjuvants
Published in Molecular pharmaceutics (07-06-2010)“…Toll-like receptor (TLR) agonists induce potent innate immune responses and can be used in the development of novel vaccine adjuvants. However, access to TLRs…”
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Whole genome sequencing of phage resistant Bacillus anthracis mutants reveals an essential role for cell surface anchoring protein CsaB in phage AP50c adsorption
Published in Virology journal (26-10-2012)“…Spontaneous Bacillus anthracis mutants resistant to infection by phage AP50c (AP50R) exhibit a mucoid colony phenotype and secrete an extracellular matrix…”
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Genomic characterization of the Yersinia genus
Published in Genome biology (04-01-2010)“…New DNA sequencing technologies have enabled detailed comparative genomic analyses of entire genera of bacterial pathogens. Prior to this study, three species…”
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Human Monoclonal Antibodies against Anthrax Lethal Factor and Protective Antigen Act Independently To Protect against Bacillus anthracis Infection and Enhance Endogenous Immunity to Anthrax
Published in Infection and Immunity (01-11-2007)“…The unpredictable nature of bioterrorism and the absence of real-time detection systems have highlighted the need for an efficient postexposure therapy for…”
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Molecular Characterization of a Variant of Bacillus anthracis-Specific Phage AP50 with Improved Bacteriolytic Activity
Published in Applied and Environmental Microbiology (01-11-2008)“…The genome sequence of a Bacillus anthracis-specific clear plaque mutant phage, AP50c, contains 31 open reading frames spanning 14,398 bp, has two mutations…”
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Recovery Efficiencies of Anthrax Spores and Ricin from Nonporous or Nonabsorbent and Porous or Absorbent Surfaces by a Variety of Sampling Methods
Published in Journal of forensic sciences (01-09-2008)“…: The 2001 anthrax letter cases brought into focus the need to establish the most effective environmental sampling procedures. Results are presented from two…”
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Rapid identification of genetic modifications in Bacillus anthracis using whole genome draft sequences generated by 454 pyrosequencing
Published in PloS one (25-08-2010)“…The anthrax letter attacks of 2001 highlighted the need for rapid identification of biothreat agents not only for epidemiological surveillance of the…”
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The US Capitol Bioterrorism Anthrax Exposures: Clinical Epidemiological and Immunological Characteristics
Published in The Journal of infectious diseases (15-01-2007)“…BackgroundBioterrorism-related anthrax exposures occurred at the US Capitol in 2001. Exposed individuals received antibiotics and anthrax vaccine adsorbed…”
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BLASTPLOT: a PERL module to plot next generation sequencing NCBI-BLAST results
Published in Source code for biology and medicine (31-03-2014)“…The development of Next Generation Sequencing (NGS) during the last decade has created an unprecedented amount of sequencing data, as well as the ability to…”
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The Bacillus anthracis chromosome contains four conserved, excision-proficient, putative prophages
Published in BMC microbiology (06-04-2006)“…Bacillus anthracis is considered to be a recently emerged clone within the Bacillus cereus sensu lato group. The B. anthracis genome sequence contains four…”
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Protection against Anthrax Lethal Toxin Challenge by Genetic Immunization with a Plasmid Encoding the Lethal Factor Protein
Published in Infection and Immunity (01-07-2001)“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Genotyping of Bacillus cereus strains by microarray-based resequencing
Published in PloS one (02-07-2008)“…The ability to distinguish microbial pathogens from closely related but nonpathogenic strains is key to understanding the population biology of these…”
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The early humoral immune response to Bacillus anthracistoxins in patients infected with cutaneous anthrax
Published in FEMS immunology and medical microbiology (01-07-2011)“…Bacillus anthracis, the causative agent of anthrax, produces a tripartite toxin composed of two enzymatically active subunits, lethal factor (LF) and edema…”
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The early humoral immune response to Bacillus anthracis toxins in patients infected with cutaneous anthrax
Published in FEMS immunology and medical microbiology (01-07-2011)“…Abstract Bacillus anthracis, the causative agent of anthrax, produces a tripartite toxin composed of two enzymatically active subunits, lethal factor (LF) and…”
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Immune response to two different dosing schedules of the anthrax vaccine precipitated (AVP) vaccine
Published in Vaccine (10-08-2007)“…Abstract A pilot study compared the immune response of regular (0, 3, 6, 32 weeks) and extended (0, 10, 13, 32 weeks) schedules of the UK anthrax vaccine…”
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Genetic immunization against anthrax
Published in Vaccine (16-04-2004)“…The objective of this study was to determine whether a DNA prime-protein boost immunization against the Bacillus anthracis protective antigen (PA) and lethal…”
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