Search Results - "MATEAR, P."

HIV infection alters the production of both type 1 and 2 cytokines but does not induce a polarized type 1 or 2 state by FAKOYA, A, MATEAR, P. M, FILLEY, E, ROOK, G. A. W, STANFORD, J, GILSON, R. J. C, BEECHAM, N, WELLER, I. V. D, VYAKARNAM, A

“…To test the T-helper (TH)1/TH2 cytokine paradigm in HIV infection. Cytokine profiles in two separate studies of HIV patients and controls are presented: (i) a…”
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HIV-1 infection of human CD4+ T cells in vitro. Differential induction of apoptosis in these cells by Martin, SJ, Matear, PM, Vyakarnam, A

“…The H9 and CEM CD4+ T cell lines were infected with HIV-1 (NY5/LAV-1 isolate) and monitored for losses in cell viability, syncytium formation, and…”
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Th1 cells specific for HIV-1 gag p24 are less efficient than Th0 cells in supporting HIV replication, and inhibit virus replication in Th0 cells by Vyakarnam, A, Matear, P M, Martin, S J, Wagstaff, M

“…This report provides three lines of evidence to suggest that T-helper type 1 (Th1) and type 0 (Th0) cells could play an opposing role in acquired immune…”
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Altered production of tumour necrosis factors alpha and beta and interferon gamma by HIV‐infected individuals by VYAKARNAM, A., MATEAR, P., MEAGER, A., KELLY, G., STANLEY, B., WELLER, I., BEVERLEY, P.

“…SUMMARY In vitro studies shows that recombinant tumour necrosis factor (TNF) α and β, and interferon‐gamma (IFN‐γ) can enhance HIV replication, and peripheral…”
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The activation of Langerhans cells in oral lichen planus by Farthing, P M, Matear, P, Cruchley, A T

“…The numbers of CD1, HLADR, HLADP and HLADQ positive, intraepithelial, dendritic cells were compared in lesions of oral lichen planus and normal oral mucosa…”
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CD7 expression distinguishes subsets of CD4+ T cells with distinct functional properties and ability to support replication of HIV‐1 by Wallace, Diana L., Matear, Patricia M., Davies, Derek C., Hicks, Ray, Lebosse, Christelle, Eyeson, Josiah, Beverley, Peter C. L., Vyakarnam, Annapurna

“…Enrichment of a subset of CD4+CD45R0+CD7– T cells has been observed in HIV‐infected individuals. We have investigated the ability of CD7+ and CD7– T cells to…”
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The immune response to HIV gp120 induced by nucleic acid immunization (NAI) by Peet, N, Delves, P J, de Souza, B, Cambridge, G, Wilkinson, L, Klonisch, T, Matear, P, Vyakarnam, A, Lund, T

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Langerhans cell distribution and keratinocyte expression of HLADR in oral lichen planus by Farthing, P M, Matear, P, Cruchley, A T

“…Keratinocyte expression of the Class II major histocompatibility complex antigen HLADR, is seen in several inflammatory disorders of skin and mucosa, including…”
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T cell responses to peptides covering the gag p24 region of HIV-1 occur in HIV-1 seronegative individuals by Vyakarnam, A, Matear, P M, Cranenburg, C, Michie, C, Beverley, P C, Wahren, B, Gill, S K, Weller, I

“…We demonstrate that peptides (16 amino acids long) covering the sequence of the HIV-1 core protein p24 induce significant proliferation in peripheral blood…”
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CD7 expression distinguishes subsets of CD4 super(+) T cells with distinct functional properties and ability to support replication of HIV-1 by Wallace, D L, Matear, P M, Davies, D C, Hicks, R, Lebosse, C, Eyeson, J, Beverley, PCL, Vyakarnam, A

“…Enrichment of a subset of CD4 super(+)CD45R0 super(+)CD7 super(-)T cells has been observed in HIV-infected individuals. We have investigated the ability of CD7…”
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HIV infection alters the production of both type 1 and 2 cytokines but does not reduce a polarized type 1 or 2 state by Fakoya, A, Matear, P M, Filley, E, Rook, GAW, Stanford, J, Gilson, RJC, Beecham, N, Weller, IVD, Vyakarnam, A

“…Our objective was to test the T-helper (TH)1/TH2 cytokine paradigm in HIV infection. Our observations did not suggest polarization of the type 1/type 2…”
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HIV-1 infection of human CD4 super(+) T cells in vitro. Differential induction of apoptosis in these cells by Martin, S J, Matear, P M, Vyakarnam, A

“…The H9 and CEM CD4 super(+) T cell lines were infected with HIV-1 (NY5/LAV-1 isolate) and monitored for losses in cell viability, syncytium formation, and…”
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Immunization of human HIV-seronegative volunteers with recombinant p17/p24:Ty virus-like particles elicits HIV-1 p24-specific cellular and humoral immune responses by Martin, S J, Vyakarnam, A, Cheingsong-Popov, R, Callow, D, Jones, K L, Senior, J M, Adams, S E, Kingsman, A J, Matear, P, Gotch, F M

“…To evaluate the immune response to HIV-1 p24 generated in vivo by p17/p24:Ty virus-like particles (p17/p24:Ty-VLP) by examining the lymphoproliferative and…”
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