Search Results - "MASUDA, Kouhei"

S6K1 Plays a Critical Role in Early Adipocyte Differentiation by Carnevalli, Larissa S., Masuda, Kouhei, Frigerio, Francesca, Le Bacquer, Olivier, Um, Sung Hee, Gandin, Valentina, Topisirovic, Ivan, Sonenberg, Nahum, Thomas, George, Kozma, Sara C.

“…Earlier, we reported that S6K1 −/− mice have reduced body fat mass, have elevated rates of lipolysis, have severely decreased adipocyte size, and are resistant…”
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Tuberin Regulates Prostaglandin Receptor-Mediated Viability, via Rheb, in mTORC1-Hyperactive Cells by Li, Chenggang, Liu, Xiaolei, Liu, Yang, Zhang, Erik, Medepalli, Kantha, Masuda, Kouhei, Li, Na, Wikenheiser-Brokamp, Kathryn A, Osterburg, Andrew, Borchers, Michael T, Kopras, Elizabeth J, Plas, David R, Sun, Julia, Franz, David N, Capal, Jamie K, Mays, Maxwell, Sun, Yang, Kwiatkowski, David J, Alayev, Anya, Holz, Marina K, Krueger, Darcy A, Siroky, Brian J, Yu, Jane J

“…Tuberous sclerosis complex (TSC) is a tumor-suppressor syndrome affecting multiple organs, including the brain, skin, kidneys, heart, and lungs. TSC is…”
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MKP-7, a Novel Mitogen-activated Protein Kinase Phosphatase, Functions as a Shuttle Protein by Masuda, Kouhei, Shima, Hiroshi, Watanabe, Masahiko, Kikuchi, Kunimi

“…Mitogen-activated protein kinase (MAPK) phosphatases (MKPs) negatively regulate MAPK activity. In the present study, we have identified a novel MKP, designated…”
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Activation of ERK Induces Phosphorylation of MAPK Phosphatase-7, a JNK Specific Phosphatase, at Ser-446 by Masuda, Kouhei, Shima, Hiroshi, Katagiri, Chiaki, Kikuchi, Kunimi

“…We previously showed that MKP-7 suppresses MAPK activation in COS-7 cells in the order of selectivity, JNK ≫ p38 > ERK, but interacts with ERK as well as JNK…”
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Phosphorylation of Ser-446 Determines Stability of MKP-7 by Katagiri, Chiaki, Masuda, Kouhei, Urano, Takeshi, Yamashita, Katsumi, Araki, Yoshio, Kikuchi, Kunimi, Shima, Hiroshi

“…MAPK cascades can be negatively regulated by members of the MAPK phosphatase (MKP) family. However, how MKP activity is regulated is not well characterized…”
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DUSP13B/TMDP inhibits stress-activated MAPKs and suppresses AP-1-dependent gene expression by Katagiri, Chiaki, Masuda, Kouhei, Nomura, Miyuki, Tanoue, Kan, Fujita, Shoko, Yamashita, Yoji, Katakura, Ryuichi, Shiiba, Ken-ichi, Nomura, Eiki, Sato, Masami, Tanuma, Nobuhiro, Shima, Hiroshi

“…The dual-specificity phosphatase (DUSP) 13 gene encodes two atypical DUSPs, DUSP13B/TMDP and DUSP13A/MDSP using alternative exons. DUSP13B protein is most…”
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Asymmetric Alkylation of 2-Monosubstituted Indolin-3-ones by Kawasaki, Tomomi, Higuchi, Kazuhiro, Masuda, Kouhei, Koseki, Tamami, Hatori, Masahiro, Sakamoto, Masanori

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Involvement of S6K1 in mitochondria function and structure in HeLa cells by Park, Jisoo, Tran, Quangdon, Mun, Kisun, Masuda, Kouhei, Kwon, So Hee, Kim, Seon-Hwan, Kim, Dong-Hoon, Thomas, George, Park, Jongsun

“…The major biological function of mitochondria is to generate cellular energy through oxidative phosphorylation. Apart from cellular respiration, mitochondria…”
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Proapoptotic protein Bim attenuates estrogen-enhanced survival in lymphangioleiomyomatosis by Li, Chenggang, Li, Na, Liu, Xiaolei, Zhang, Erik Y, Sun, Yang, Masuda, Kouhei, Li, Jing, Sun, Julia, Morrison, Tasha, Li, Xiangke, Chen, Yuanguang, Wang, Jiang, Karim, Nagla A, Zhang, Yi, Blenis, John, Reginato, Mauricio J, Henske, Elizabeth P, Yu, Jane J

“…Lymphangioleiomyomatosis (LAM) is a progressive lung disease that primarily affects young women. Genetic evidence suggests that LAM cells bearing mutations…”
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Novel function of MKP-5/DUSP10, a phosphatase of stress-activated kinases, on ERK-dependent gene expression, and upregulation of its gene expression in colon carcinomas by NOMURA, Miyuki, SHIIBA, Ken-Ichi, NAKAMURA, Yoshihiro, NAGATA, Toshiyuki, OTSUKA, Tsunayuki, KATAKURA, Ryuichi, YAMASHITA, Yoji, SATO, Masami, TANUMA, Nobuhiro, SHIMA, Hiroshi, KATAGIRI, Chiaki, KASUGAI, Isao, MASUDA, Kouhei, SATO, Ikuro, SATO, Masayuki, KAKUGAWA, Yoichiro, NOMURA, Eiki, HAYASHI, Katsuhisa

“…Mitogen-activated protein kinase phosphatase 5 (MKP-5)/DUSP10 acts as a phosphatase of stress-activated kinases (JNK and p38), but its activity towards ERK has…”
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MKP-7, a JNK phosphatase, blocks ERK-dependent gene activation by anchoring phosphorylated ERK in the cytoplasm by Masuda, Kouhei, Katagiri, Chiaki, Nomura, Miyuki, Sato, Masami, Kakumoto, Kyoko, Akagi, Tsuyoshi, Kikuchi, Kunimi, Tanuma, Nobuhiro, Shima, Hiroshi

“…MAPK phosphatase-7 (MKP-7) was identified as a JNK-specific phosphatase. However, despite its high specificity for JNK, MKP-7 interacts also with ERK. We…”
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Characterization of a novel low-molecular-mass dual-specificity phosphatase-3 (LDP-3) that enhances activation of JNK and p38 by Takagaki, Kentaro, Satoh, Takeshi, Tanuma, Nobuhiro, Masuda, Kouhei, Takekawa, Mutsuhiro, Shima, Hiroshi, Kikuchi, Kunimi

“…We have isolated a mouse cDNA for a novel dual-specificity phosphatase designated LDP-3 (low-molecular-mass dual-specificity phosphatase 3). The 450 bp open…”
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Reverse Aromatic Cope Rearrangement of 2-Allyl-3-alkylideneindolines Driven by Olefination of 2-Allylindolin-3-ones:  Synthesis of α-Allyl-3-indole Acetate Derivatives by Kawasaki, Tomomi, Nonaka, Yoshinori, Watanabe, Kazuaki, Ogawa, Atsuyo, Higuchi, Kazuhiro, Terashima, Romi, Masuda, Kouhei, Sakamoto, Masanori

“…The reverse aromatic Cope rearrangement of 2-allyl-3-alkylideneindolines obtained by Horner−Wadsworth−Emmons olefination of 2-allylindolin-3-ones was…”
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SYNTHESIS OF 1, 2-DIHYDRO-2-ALLYLINDOL-3-ONES USING IN SITU CLAISEN REARRANGEMENT OF 1, 2-DIHYDROINDOL-3-ONES WITH ALLYL ALCOHOLS by KAWASAKI, Tomomi, MASUDA, Kouhei, BABA, Yasutaka, TAKADA, Kana, SAKAMOTO, Masanori

“…Thermal treatment of 1, 2-dihydroindol-3-ones (2) with allyl alcohols (3) in the presence of camphorsulfonic acid and magnesium sulfate advances a sequence of…”
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Synthesis of 1,2-Dihydro-2-allylindol-3-ones Using in Situ Claisen Rearrengement of 1,2-Dihydroindol-3-ones with Allyl Alcohols by KAWASAKI, Tomomi, MASUDA, Kouhei, BABA, Yasutaka, TAKADA, Kana, SAKAMOTO, Masanori

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