Search Results - "MASTRANGELO, Domenico"
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Mechanisms of anti-cancer effects of ascorbate: Cytotoxic activity and epigenetic modulation
Published in Blood cells, molecules, & diseases (01-03-2018)“…Vitamin C (Vit C or Ascorbate) is essential for many fundamental biochemical processes. Vit C is an essential nutrient with redox functions at normal…”
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Cytotoxic effects of high concentrations of sodium ascorbate on human myeloid cell lines
Published in Annals of hematology (01-11-2015)“…The effect of high doses of intravenous (sodium) ascorbate (ASC) in the treatment of cancer has been controversial although there is growing evidence that ASC…”
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Aberrant promoter methylation and silencing of the RASSF1A gene in pediatric tumors and cell lines
Published in Oncogene (20-06-2002)“…Aberrant promoter methylation of tumor suppressor genes has not been fully investigated in pediatric tumors. Therefore, we examined the methylation status of…”
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Aberrant Methylation of the HIC1 Promoter Is a Frequent Event in Specific Pediatric Neoplasms
Published in Clinical cancer research (01-09-2003)“…Purpose: To determine the role of methylation of HIC1 , a candidate tumor suppressor gene on 17p13.3, in various types of pediatric tumors. Experimental…”
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Retinoblastoma and the Genetic Theory of Cancer: An Old Paradigm Trying to Survive to the Evidence
Published in Journal of Cancer Epidemiology (01-01-2009)“…Retinoblastoma (Rb) is considered to represent the prototype of cancer linked to the sequential loss or inactivation of both alleles of a so-called “tumor…”
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Sceptical views on homeopathy: Do we really need "sceptical" homeopaths?
Published in Homeopathy : the journal of the Faculty of Homeopathy (01-10-2010)Get more information
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Hormesis, epitaxy, the structure of liquid water, and the science of homeopathy
Published in Medical science monitor (01-01-2007)“…According to the western medical establishment, homeopathy is both "unscientific" and "implausible". A short overview of its history and the methods it uses,…”
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High-dose ascorbate and arsenic trioxide selectively kill acute myeloid leukemia and acute promyelocytic leukemia blasts in vitro
Published in Oncotarget (16-05-2017)“…The use of high-dose ascorbate (ASC) for the treatment of human cancer has been attempted several decades ago and has been recently revived by several in vitro…”
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Prevalence of allostatic overload syndrome in patients with chronic cardiovascular disease
Published in Psychotherapy and psychosomatics (01-01-2012)Get more information
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Adrenaline inhibits the immunological activation of human basophils at pharmacological and ultra-low doses
Published in Medical science monitor (01-07-2010)“…Adrenaline is known to inhibit the immunological activation of human basophils. The same effect can be obtained with ultra-low doses of histamine. The present…”
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Pathogenesis of posterior capsular opacification. Part II: Histopathological and in vitro culture findings
Published in Journal of cataract and refractive surgery (01-05-1990)“…The most interesting sources of information about the pathogenesis of posterior capsular opacification seem to be histopathological studies and in vitro tissue…”
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Does the evidence matter in medicine? The retinoblastoma paradigm
Published in International journal of cancer (01-12-2007)“…Retinoblastoma (Rb) is the most common intraocular malignant tumour in childhood, with an incidence of 1 in 15,000 live births. Complete information on this…”
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Individualising cancer chemotherapy: a new paradigm with roots in an old tradition
Published in European journal of integrative medicine (01-09-2012)Get full text
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Deregulation of Caspase 8 and 10 expression in pediatric tumors and cell lines
Published in Cancer research (Chicago, Ill.) (15-10-2002)“…Methylation of the promoter regions of CpG-rich sites in genes is the major mechanism for the silencing of many genes in tumors. Methylation of the key…”
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Massive anterior chamber involvement after Intra-arterial chemotherapy for retinoblastoma: ultrasound biomicroscopy and histopathology
Published in International ophthalmology (01-08-2014)“…This case report highlights the usefulness of Ultrasound Biomicroscopy (UBM) in a case of retinoblastoma which showed massive anterior chamber involvement…”
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The retinoblastoma paradigm revisited
Published in Medical science monitor (01-12-2008)“…Retinoblastoma (Rb) is the most common primary malignant intraocular tumour in childhood. The "two hit" theory, formulated by Knudson in 1971 to explain the…”
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Successful treatment of macular retinoblastoma with superselective ophthalmic artery infusion of melphalan
Published in Journal of pediatric ophthalmology and strabismus (01-01-2014)“…To report our experience with superselective ophthalmic artery infusion of melphalan (SOAIM) for macular retinoblastoma to obtain tumor control while…”
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Growth of congenital malignant teratoid medulloepithelioma of the ciliary body: a case study
Published in Journal of neuro-oncology (01-02-2010)“…The purpose of this study was to describe the growth pattern of congenital malignant teratoid medulloepithelioma of the ciliary body by reporting clinical and…”
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The epigenetic origin of retinoblastoma: how the environment steadily impresses its effects on the genome
Published in European journal of integrative medicine (01-09-2012)Get full text
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