Search Results - "MASAGUER, C. F"

New Serotonin 5-HT2A, 5-HT2B, and 5-HT2C Receptor Antagonists:  Synthesis, Pharmacology, 3D-QSAR, and Molecular Modeling of (Aminoalkyl)benzo and Heterocycloalkanones by Brea, José, Rodrigo, Jordi, Carrieri, Antonio, Sanz, Ferran, Cadavid, M. Isabel, Enguix, María J, Villazón, María, Mengod, Guadalupe, Caro, Yolanda, Masaguer, Christian F, Raviña, Enrique, Centeno, Nuria B, Carotti, Angelo, Loza, M. Isabel

“…A series of 52 conformationally constrained butyrophenones have been synthesized and pharmacologically tested as antagonists at 5-HT2A, 5-HT2B, and 5-HT2C…”
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Synthesis and Affinities for Dopamine (D2) and 5-Hydroxytryptamine (5-HT2A) Receptors of 1-(Benzoylpropyl)-4-(1-oxocycloalkyl-2-ethyl)-piperazines as Cyclic Butyrophenone Derivatives by RAVINA, Enrique, FUEYO, Javier, MASAGUER, Christian F., NEGREIRA, Jesus, CID, Jose, LOZA, Isabel, HONRUBIA, Angeles, TRISTAN, Helena, G-FERREIRO, Tomas, FONTENLA, Jose A., ROSA, Elizabeth, CALLEJA, Jose M., CEBALLOS, Maria L. DE

“…Starting from benzo- or thienocycloalkaneacetic acids, we have prepared a series of 1-(3-p-fluorobenzoylpropyl)-4-(1-oxo-benzo- or…”
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3D printing of a palladium-alumina cermet monolithic catalyst: catalytic evaluation in microwave-assisted cross-coupling reactions by Tubio, C.R., Malatini, C., Barrio, V.L., Masaguer, C.F., Amorín, M., Nabgan, W., Taboada, P., Guitián, F., Gil, A., Coelho, A.

“…A straightforward manufacture strategy is proposed to obtain an efficient and robust palladium-alumina (Pd0/Al2O3) cermet monolithic catalyst, specifically…”
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Butyrophenone analogues in the carbazole series : Synthesis and determination of affinities at D2 and 5-HT2A receptors by MASAGUER, C. F, FORMOSO, E, RAVINA, E, TRISTAN, H, LOZA, M. I, RIVAS, E, FONTENLA, J. A

“…We describe a practical and efficient route for synthesis of 2-aminomethyl-1,2,3,9-tetrahydro-4H-carbazol-4-ones using an effective Fisher indole methodology…”
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Conformationally restricted butyrophenones with mixed dopaminergic (D2) and serotoninergic (5-HT2A) affinities. Synthesis of 5-aminoethyl-and 6-aminomethyl-4-oxotetrahydroindoles as potential atypical antipsychotics by MASAGUER, C. F, CASARIEGO, I, RAVINA, E

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Multistructure 3D-QSAR Studies on a Series of Conformationally Constrained Butyrophenones Docked into a New Homology Model of the 5-HT sub(2A) Receptor by Dezi, C, Brea, J, Alvarado, M, Ravina, E, Masaguer, C F, Loza, MI, Sanz, F, Pastor, M

“…The present study is part of a long-term research project aiming to gain insight into the mechanism of action of atypical antipsychotics. Here we describe a…”
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Alkylation of 3-ethyl-2-methyl-4-oxo-4,5,6,7-tetrahydroindole with bromoesters: benzenesulfonyl as convenient nitrogen protecting group by MASAGUER, C. F, RAVINA, E, FUEYO, J

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A simple, efficient method for regioselective synthesis of 7-aminomethyl-7,8-dihydro-6H-quinolin-5-ones, new potential CNS agents by Pita, Beatriz, Masaguer, Christian F, Raviña, Enrique

“…We have developed an efficient and convenient strategy for the regioselective synthesis of new conformationally restricted butyrophenones of the quinoline…”
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1H and 13C NMR spectroscopy of some 4-(p-fluorobenzoyl)piperidine derivatives by Masaguer, C. F., Raviña, E.

“…1H and 13C NMR spectral data for 12 N‐[(benzo‐ or heterocycloalkyl)methyl or ethyl]‐4‐(p‐fluorobenzoyl)piperidines were fully assigned by a combination of one‐…”
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1H and13C NMR spectroscopy of some 4-(p-fluorobenzoyl)piperidine derivatives by Masaguer, C. F., Raviña, E.

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Synthesis and Biological Evaluation of New Quinazoline and Cinnoline Derivatives as Potential Atypical Antipsychotics by Alvarado, Mario, Barceló, María, Carro, Laura, Masaguer, Christian F., Raviña, Enrique

“…Four new diaza analogues (14, 15, 23, and 24) of the conformationally constrained aminobutyrophenone derivatives QF0104B (5) and QF0108B (6) were synthesized…”
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Conformationally Constrained Butyrophenones with Mixed Dopaminergic (D2) and Serotoninergic (5-HT2A, 5-HT2C) Affinities:  Synthesis, Pharmacology, 3D-QSAR, and Molecular Modeling of (Aminoalkyl)benzo- and -thienocycloalkanones as Putative Atypical Antipsychotics by Raviña, Enrique, Negreira, Jesús, Cid, José, Masaguer, Christian F, Rosa, Elizabeth, Rivas, M. Emilia, Fontenla, José A, Loza, M. Isabel, Tristán, Helena, Cadavid, M. Isabel, Sanz, Ferran, Lozoya, Estrella, Carotti, Angelo, Carrieri, Antonio

“…A series of novel conformationally restricted butyrophenones (2-(aminoethyl)- and 3-(aminomethyl)thieno- or benzocycloalkanones bearing…”
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Butyrophenone analogues in the carbazole series as potential atypical antipsychotics: synthesis and determination of affinities at D(2), 5-HT(2A), 5-HT(2B) and 5-HT(2C) receptors by Masaguer, C F, Raviña, E, Fontenla, J A, Brea, J, Tristán, H, Loza, M I

“…We describe practical and efficient routes for synthesis of 2-aminomethyl-1,2,3,9-tetrahydro-4H-carbazol-4-ones using the Fischer indole synthesis or…”
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New cyclic butyrophenone derivatives in the indole series as potential atypical antipsychotics. A simple and practical synthesis of 6-aminomethyl-tetrahydroindol-4-ones and their affinities for D2 and 5-HT2A receptors by MASAGUER, C. F, RAVINA, E, LOZA, I, FONTENLA, J. A

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Butyrophenone analogues in the carbazole series as potential atypical antipsychotics : synthesis and determination of affinities at D2, 5-HT2A, 5-HT2B and 5-HT2C receptors by MASAGUER, C. F, RAVINA, E, FONTENLA, J. A, BREA, J, TRISTAN, H, LOZA, M. I

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Conformationally constrained butyrophenones with affinity for dopamine (D(1), D(2), D(4)) and serotonin (5-HT(2A), 5-HT(2B), 5-HT(2C)) receptors: synthesis of aminomethylbenzo[b]furanones and their evaluation as antipsychotics by Raviña, E, Casariego, I, Masaguer, C F, Fontenla, J A, Montenegro, G Y, Rivas, M E, Loza, M I, Enguix, M J, Villazon, M, Cadavid, M I, Demontis, G C

“…A series of novel conformationally restricted butyrophenones (6-aminomethyl-4,5,6,7-tetrahydrobenzo[b]furan-4-ones bearing…”
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Efficient synthesis of quinazolinones as intermediates of CNS agents via inverse-electron demand Diels–Alder reaction by Bilbao, Estibaliz R., Alvarado, Mario, Masaguer, Christian F., Raviña, Enrique

“…Enaminones undergo inverse electron demand Diels–Alder reaction with 1,3,5-triazine, allowing access to functionalised quinazolinones as intermediates in the…”
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Conformationally constrained butyrophenones with mixed dopaminergic (D(2)) and serotoninergic (5-HT(2A), 5-HT(2C)) affinities: synthesis, pharmacology, 3D-QSAR, and molecular modeling of (aminoalkyl)benzo- and -thienocycloalkanones as putative atypical antipsychotics by Raviña, E, Negreira, J, Cid, J, Masaguer, C F, Rosa, E, Rivas, M E, Fontenla, J A, Loza, M I, Tristán, H, Cadavid, M I, Sanz, F, Lozoya, E, Carotti, A, Carrieri, A

“…A series of novel conformationally restricted butyrophenones (2-(aminoethyl)- and 3-(aminomethyl)thieno- or benzocycloalkanones bearing…”
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Preparation of ( R)-(−)- and ( S)-(+)-3-hydroxymethyl-1-tetralone tosylates, key intermediates in the synthesis of new CNS drugs, via resolution of precursors by Caro, Yolanda, Masaguer, Christian F., Raviña, Enrique

“…The preparation of ( R)-(−)- and ( S)-(+)-3-hydroxymethyl-1-tetralone tosylates, key intermediates in the synthesis of new CNS drugs in the aminobutyrophenone…”
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Synthesis and binding affinity of novel 3-aminoethyl-1-tetralones, potential atypical antipsychotics by Alvarado, Mario, Coelho, Alberto, Masaguer, Christian F., Raviña, Enrique, Brea, José, Padín, J. Fernando, Loza, María I.

“…The preparation and binding affinities of new 3-aminoethyl-1-tetralones are reported. Some of these compounds (e.g., 6) showed potential atypical antipsychotic…”
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