Search Results - "MARX, S. J"

Diagnosis of Asymptomatic Primary Hyperparathyroidism: Proceedings of the Third International Workshop by Eastell, R., Arnold, A., Brandi, M. L., Brown, E. M., D'Amour, P., Hanley, D. A., Rao, D. Sudhaker, Rubin, M. R., Goltzman, D., Silverberg, S. J., Marx, S. J., Peacock, M., Mosekilde, L., Bouillon, R., Lewiecki, E. M.

“…Objective: Asymptomatic primary hyperparathyroidism (PHPT) is a common clinical problem. The purpose of this report is to guide the use of diagnostic tests for…”
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Markers of intestinal injury are associated with endotoxemia in successfully resuscitated patients by Grimaldi, D, Guivarch, E, Neveux, N, Fichet, J, Pène, F, Marx, J.-S, Chiche, J.-D, Cynober, L, Mira, J.-P, Cariou, A

“…Abstract Aims Gut dysfunction is suspected to play a major role in the pathophysiology of post-resuscitation disease through an increase in intestinal…”
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FGF-23 Is Elevated by Chronic Hyperphosphatemia by Gupta, A., Winer, K., Econs, M. J., Marx, S. J., Collins, M. T.

“…The Identification and characterization of FGF-23 has provided an opportunity to gain new insight into phosphorus metabolism. Circulating FGF-23 promotes renal…”
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Guidelines for diagnosis and therapy of MEN type 1 and type 2 by Brandi, M L, Gagel, R F, Angeli, A, Bilezikian, J P, Beck-Peccoz, P, Bordi, C, Conte-Devolx, B, Falchetti, A, Gheri, R G, Libroia, A, Lips, C J, Lombardi, G, Mannelli, M, Pacini, F, Ponder, B A, Raue, F, Skogseid, B, Tamburrano, G, Thakker, R V, Thompson, N W, Tomassetti, P, Tonelli, F, Wells, Jr, S A, Marx, S J

“…This is a consensus statement from an international group, mostly of clinical endocrinologists. MEN1 and MEN2 are hereditary cancer syndromes. The commonest…”
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Retour d’expérience sur la régulation au Samu de Paris pendant la crise de Covid-19 by Telion, C., Marx, J.-S., Dautreppe, C., Carli, P.

“…L’épidémie de Covid-19 représente une crise dont l’ampleur n’avait jusque-là jamais été imaginée. Des modifications des pratiques pour y faire face ne…”
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Multiple Endocrine Neoplasia – Introduction by MARX, S. J., STRATAKIS, C. A.

“… Each multiple endocrine neoplasia (MEN) syndrome expresses striking features of hormone oversecretion from its own characteristic group of tissues…”
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Stable overexpression of MEN1 suppresses tumorigenicity of RAS by KIM, Y. S, BURNS, A. L, GOLDSMITH, P. K, HEPPNER, C, PARK, S. Y, CHANDRASEKHARAPPA, S. C, COLLINS, F. S, SPIEGEL, A. M, MARX, S. J

“…Although there is indirect genetic evidence that MEN1, the gene for multiple endocrine neoplasia type 1, is a tumor suppressor gene, little is known about the…”
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Menin molecular interactions: insights into normal functions and tumorigenesis by Agarwal, S K, Kennedy, P A, Scacheri, P C, Novotny, E A, Hickman, A B, Cerrato, A, Rice, T S, Moore, J B, Rao, S, Ji, Y, Mateo, C, Libutti, S K, Oliver, B, Chandrasekharappa, S C, Burns, A L, Collins, F S, Spiegel, A M, Marx, S J

“…Multiple endocrine neoplasia type 1 (MEN1) is an autosomal dominant disease predisposed by heterozygous germline mutations in the MEN1 tumor suppressor gene…”
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Germline Mutations of the MEN1 Gene in Familial Multiple Endocrine Neoplasia Type 1 and Related States by Agarwal, Sunita K., Beth Kester, Mary, Debelenko, Larisa V., Heppner, Christina, Emmert-Buck, Michael R., Skarulis, Monica C., Doppman, John L., Kim, Young S., Lubensky, Irina A., Zhuang, Zhengping, Green, Jane S., Guru, Sirandanahalli C., Manickam, Pachiappan, Olufemi, Shodimu-Emmanuel, Liotta, Lance A., Chandrasekharappa, Settara C., Collins, Francis S., Spiegel, Allen M., Lee Burns, A., Marx, Stephen J.

“…Familial multiple endocrine neoplasia type 1 (FMEN1) is an autosomal dominant trait characterized by tumors of the parathyroids, gastro-intestinal endocrine…”
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Treatment of hypercalcemia secondary to parathyroid carcinoma with a novel calcimimetic agent by COLLINS, M. T, SKARULIS, M. C, BILEZIKIAN, J. P, SILVERBERG, S. J, SPIEGEL, A. M, MARX, S. J

“…Parathyroid carcinoma is one cause of primary hyperparathyroidism, a condition in which there is hypercalcemia and dysregulated hypersecretion of PTH. In…”
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Cutaneous Tumors in Patients with Multiple Endocrine Neoplasia Type 1 Show Allelic Deletion of the MEN1 Gene by Pack, Svetlana, Turner, Maria L., Zhuang, Zhengping, Vortmeyer, Alexander O., Böni, Roland, Skarulis, Monica, Marx, Stephen J., Darling, Thomas N.

“…Multiple endocrine neoplasia type 1 (MEN1), the heritable tendency to develop tumors of the parathyroid, pituitary, and entero-pancreatic endocrine tissues, is…”
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Progression of uremic hyperparathyroidism involves allelic loss on chromosome 11 by Falchetti, A, Bale, A E, Amorosi, A, Bordi, C, Cicchi, P, Bandini, S, Marx, S J, Brandi, M L

“…In occasional cases of secondary hyperparathyroidism, long term stimulation of the parathyroid glands leads from compensatory to autonomous hyperfunction, and…”
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Multiple endocrine neoplasias in the era of translational medicine by Stratakis, C A, Marx, S J

“…Medicine is an ever changing art, continuously adjusting to the shifting principles of philosophy and constant discoveries of science; it was beautifully said…”
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MEN1 gene analysis in sporadic adrenocortical neoplasms by HEPPNER, C, REINCKE, M, AGARWAL, S. K, MORA, P, ALLOLIO, B, BURNS, A. L, SPIEGEL, A. M, MARX, S. J

“…Adrenocortical tumors occur as sporadic tumors, as part of the multiple endocrine neoplasia type 1 (MEN1) syndrome or as part of other hereditary disorders. We…”
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Bidirectional transcriptional activity of PGK-neomycin and unexpected embryonic lethality in heterozygote chimeric knockout mice by Scacheri, P.C., Crabtree, J.S., Novotny, E.A., Garrett-Beal, L., Chen, A., Edgemon, K.A., Marx, S.J., Spiegel, A.M., Chandrasekharappa, S.C., Collins, F.S.

“…In an effort to create a conventional knockout mouse model for multiple endocrine neoplasia type 1 (MEN1), we targeted disruption of the mouse Men1 gene…”
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Allelic deletions on chromosome 11q13 in multiple endocrine neoplasia type 1-associated and sporadic gastrinomas and pancreatic endocrine tumors by DEBELENKO, L. V, ZHUANG, Z, JENSEN, R. T, LIOTTA, L. A, LUBENSKY, I. A, EMMERT-BUCK, M. R, CHANDRASEKHARAPPA, S. C, MANICKAM, P, GURU, S. C, MARX, S. J, SKARULIS, M. C, SPIEGEL, A. M, COLLINS, F. S

“…Endocrine tumors (ETs) of pancreas and duodenum occur sporadically and as a part of multiple endocrine neoplasia type 1 (MEN1). The MEN1 tumor suppressor gene…”
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Familial hypocalciuric hypercalcemia and neonatal severe hyperparathyroidism : effects of mutant gene dosage on phenotype by POLLAK, M. R, YAH-HUEI CHOU, SEIDMAN, C. E, SEIDMAN, J. G, MARX, S. J, STEINMANN, B, COLE, D. E. C, BRANDI, M. L, PAPAPOULOS, S. E, MENKO, F. H, HENDY, G. N, BROWN, E. M

“…Neonatal severe hyperparathyroidism is a rare life-threatening disorder characterized by very high serum calcium concentrations (> 15 mg/dl). Many cases have…”
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Identification and characterization of JunD missense mutants that lack menin binding by KNAPP, J. I, HEPPNER, C, HICKMAN, A. B, BURNS, A. L, CHANDRASEKHARAPPA, S. C, COLLINS, F. S, MARX, S. J, SPIEGEL, A. M, AGARWAL, S. K

“…Menin, the product of the MEN1 tumor suppressor gene, binds to the AP1 transcription factor JunD and represses JunD transcriptional activity. The effects of…”
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Technetium-99m-Sestamibi Imaging before Reoperation for Primary Hyperparathyroidism by Chen, Clara C, Skarulis, Monica C, Fraker, Douglas L, Alexander, H. Richard, Marx, Stephen J, Spiegel, Allen M

“…Recent studies have reported high sensitivities for parathyroid localization with 99mTc-sestamibi and have been performed using either 123I/99mTc-sestamibi or…”
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Increased basic fibroblast growth factor in plasma from multiple endocrine neoplasia type 1: relation to pituitary tumor by Zimering, M B, Katsumata, N, Sato, Y, Brandi, M L, Aurbach, G D, Marx, S J, Friesen, H G

“…Multiple endocrine neoplasia type 1 (MEN1) is an autosomal dominant disorder characterized by tumors of the parathyroids, pancreatic islets, and anterior…”
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