Search Results - "MARTINOVIC, Dalma"
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The Eco‐Exposome Concept: Supporting an Integrated Assessment of Mixtures of Environmental Chemicals
Published in Environmental toxicology and chemistry (01-01-2022)“…Organisms are exposed to ever‐changing complex mixtures of chemicals over the course of their lifetime. The need to more comprehensively describe this exposure…”
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Endocrine disrupting chemicals in fish: Developing exposure indicators and predictive models of effects based on mechanism of action
Published in Aquatic toxicology (05-05-2009)“…Knowledge of possible toxic mechanisms (or modes) of action (MOA) of chemicals can provide valuable insights as to appropriate methods for assessing exposure…”
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3
Environmental estrogens suppress hormones, behavior, and reproductive fitness in male fathead minnows
Published in Environmental toxicology and chemistry (01-02-2007)“…—This study explored the possibility that environmental estrogens in sewage effluent may reduce the reproductive fitness of adult male fish by suppressing…”
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4
Effects of progesterone and norethindrone on female fathead minnow (Pimephales promelas) steroidogenesis
Published in Environmental toxicology and chemistry (01-02-2015)“…As knowledge of contaminants capable of adversely modulating endocrine functions increases, attention is focused on the effects of synthetic progestins as…”
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5
Temporal Variation in the Estrogenicity of a Sewage Treatment Plant Effluent and Its Biological Significance
Published in Environmental science & technology (01-05-2008)“…Daily variation in the estrogenic activity of effluent released by a modern sewage treatment plant (STP) was measured and its effects on the physiology,…”
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6
Gene expression profiling of the androgen receptor antagonists flutamide and vinclozolin in zebrafish ( Danio rerio) gonads
Published in Aquatic toxicology (25-01-2011)“…The studies presented in this manuscript focus on characterization of transcriptomic responses to anti-androgens in zebrafish ( Danio rerio). Research on the…”
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A study of temporal effects of the model anti-androgen flutamide on components of the hypothalamic-pituitary-gonadal axis in adult fathead minnows
Published in Aquatic toxicology (01-11-2016)“…•Flutamide causes rapid effects on reproductive endocrinology of adult fathead minnows.•Apical effects of flutamide include demasculinization of males and…”
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8
Direct Effects, Compensation, and Recovery in Female Fathead Minnows Exposed to a Model Aromatase Inhibitor
Published in Environmental health perspectives (01-04-2009)“…Background: Several chemicals in the environment have the potential to inhibit aromatase, an enzyme critical to estrogen synthesis. Objectives: The objective…”
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Constraints-based stoichiometric analysis of hypoxic stress on steroidogenesis in fathead minnows, Pimephales promelas
Published in Journal of experimental biology (15-05-2012)“…In this study, an in silico genome-scale metabolic model of steroidogenesis was used to investigate the effects of hypoxic stress on steroid hormone…”
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10
Transcription of Key Genes Regulating Gonadal Steroidogenesis in Control and Ketoconazole- or Vinclozolin-Exposed Fathead Minnows
Published in Toxicological sciences (01-08-2007)“…This study evaluated changes in the expression of steroidogenesis-related genes in male fathead minnows exposed to ketoconazole (KTC) or vinclozolin (VZ) for…”
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11
In Silico analysis of perturbed steroidogenesis and gonad growth in fathead minnows (P. promelas) exposed to 17α-ethynylestradiol
Published in Systems biology in reproductive medicine (01-06-2015)“…Abstract The multi-factorial nature of adverse reproductive effects mediated by endocrine disrupting compounds (or EDCs) makes understanding the mechanistic…”
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12
Assessment of Mitochondrial Function in the AmE‐711 Honey Bee Cell Line: Boscalid and Pyraclostrobin Effects
Published in Environmental toxicology and chemistry (01-05-2024)“…There is a growing concern that chronic exposure to fungicides contributes to negative effects on honey bee development, life span, and behavior. Field and…”
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13
Rapid effects of the aromatase inhibitor fadrozole on steroid production and gene expression in the ovary of female fathead minnows (Pimephales promelas)
Published in General and comparative endocrinology (01-10-2017)“…•Estradiol concentrations were altered within hours of exposure to fadrozole.•Estradiol remained depressed over the first 24h of exposure.•Gene expression…”
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14
Effects of a short-term exposure to the fungicide prochloraz on endocrine function and gene expression in female fathead minnows ( Pimephales promelas)
Published in Aquatic toxicology (01-06-2011)“…Prochloraz is a fungicide known to cause endocrine disruption through effects on the hypothalamic–pituitary–gonadal (HPG) axis. To determine the short-term…”
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15
Toxicity prediction and effect characterization of 90 pharmaceuticals and illicit drugs measured in plasma of fish from a major European river (Sava, Croatia)
Published in Environmental pollution (1987) (01-11-2020)“…Chemical analysis of plasma samples of wild fish from the Sava River (Croatia) revealed the presence of 90 different pharmaceuticals/illicit drugs and their…”
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Fishy aroma of social status: urinary chemo-signalling of territoriality in male fathead minnows (Pimephales promelas)
Published in PloS one (07-11-2012)“…Chemical structures of several urinary reproductive pheromones in fish have been identified, and their role in the chemical communication of reproductive…”
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17
I. Effects of a dopamine receptor antagonist on fathead minnow, Pimephales promelas, reproduction
Published in Ecotoxicology and environmental safety (01-05-2010)“…Neurotransmitters such as dopamine play an important role in regulating fish reproduction. However, the potential for neuroendocrine active chemicals to…”
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II: Effects of a dopamine receptor antagonist on fathead minnow dominance behavior and ovarian gene expression in the fathead minnow and zebrafish
Published in Ecotoxicology and environmental safety (01-05-2010)“…Neurotransmitters such as dopamine play an important role in reproductive behaviors and signaling. Neuroendocrine-active chemicals in the environment have…”
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Biological Effects of Hydrocarbon Degradation Intermediates: Is the Total Petroleum Hydrocarbon Analytical Method Adequate for Risk Assessment?
Published in Environmental science & technology (15-09-2020)“…In crude oil contaminant plumes, the dissolved organic carbon (DOC) is mainly hydrocarbon degradation intermediates only partly quantified by the diesel range…”
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Toxicity Assessment of Groundwater Contaminated by Petroleum Hydrocarbons at a Well-Characterized, Aged, Crude Oil Release Site
Published in Environmental science & technology (06-11-2018)“…Management of petroleum-impacted waters by monitored natural attenuation requires an understanding of the toxicology of both the original compounds released…”
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