Search Results - "MARTIN, TRACEY A"
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The role of tight junctions in cancer metastasis
Published in Seminars in cell & developmental biology (01-12-2014)“…Over the last decade, it has become apparent that the tight junction (TJ) is a key component in tumour progression and metastasis. In addition to its role in…”
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Loss of tight junction barrier function and its role in cancer metastasis
Published in Biochimica et biophysica acta (01-04-2009)“…As the most apical structure between epithelial and endothelial cells, tight junctions (TJ) are well known as functioning as a control for the paracellular…”
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Tim-3 promotes cell aggressiveness and paclitaxel resistance through NF-κB/STAT3 signalling pathway in breast cancer cells
Published in Chinese journal of cancer research (31-10-2020)“…Although T-cell immunoglobulin and mucin-domain containing molecule-3 (Tim-3) has been recognized as a promising target for cancer immunotherapy, its exact…”
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The role of claudin-5 in blood-brain barrier (BBB) and brain metastases (Review)
Published in Molecular medicine reports (01-03-2014)“…Metastatic brain tumours are frequently observed in patients with lung, breast and malignant melanoma and a severe complication of metastatic cancers. With…”
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Methamphetamine causes differential alterations in gene expression and patterns of histone acetylation/hypoacetylation in the rat nucleus accumbens
Published in PloS one (28-03-2012)“…Methamphetamine (METH) addiction is associated with several neuropsychiatric symptoms. Little is known about the effects of METH on gene expression and…”
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Tight junctions in cancer metastasis
Published in Frontiers in bioscience (01-01-2011)“…Tight Junctions (TJ) are well known to function as a control for the paracellular diffusion of ions and certain molecules, it has however, become evident that…”
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Striatins and STRIPAK complex partners in clinical outcomes of patients with breast cancer and responses to drug treatment
Published in Chinese journal of cancer research (30-08-2023)“…ObjectiveStriatins (STRNs) family, which contains three multi-domain scaffolding proteins, are cornerstones of the striatins interacting phosphatase and kinase…”
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The expression of the Nectin complex in human breast cancer and the role of Nectin-3 in the control of tight junctions during metastasis
Published in PloS one (26-12-2013)“…Nectins are a family of integral protein molecules involved in the formation of functioning Adherens and Tight Junctions (TJ). Aberrant expression is…”
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Effect of junctional adhesion molecule-2 expression on cell growth, invasion and migration in human colorectal cancer
Published in International journal of oncology (01-03-2016)“…The junctional adhesion molecule (JAMs) family belongs to the immunoglobulin subfamily involved in the formation of tight junctions (TJ) in both endothelial…”
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Neural Wiskott-Aldrich syndrome protein (nWASP) is implicated in human lung cancer invasion
Published in BMC cancer (28-03-2017)“…Lung cancer is one of the most commonly diagnosed cancers with survival much lower in patients diagnosed with distal metastases. It is therefore imperative to…”
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Claudin-5 is involved in breast cancer cell motility through the N-WASP and ROCK signalling pathways
Published in Journal of experimental & clinical cancer research (04-05-2012)“…Recent studies have shown dysregulation in TJ structure of several cancers including breast. Claudin-5 is a protein member of the TJ structure expressed in…”
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Eplin-alpha expression in human breast cancer, the impact on cellular migration and clinical outcome
Published in Molecular cancer (16-09-2008)“…To investigate the expression of EPLIN-alpha, epithelial protein lost in neoplasm, in human breast cancer tissues/cells and investigate the cellular impact of…”
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13
nWASP Inhibition Increases Wound Healing via TrKb/PLCγ Signalling
Published in Biomolecules (Basel, Switzerland) (01-02-2023)“…(1) Background: Chronic wounds represent a major burden to patients and healthcare systems and identifying new therapeutic targets to encourage wound healing…”
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Expression of Claudin-9 (CLDN9) in Breast Cancer, the Clinical Significance in Connection with Its Subcoat Anchorage Proteins ZO-1 and ZO-3 and Impact on Drug Resistance
Published in Biomedicines (24-11-2023)“…(1) Introduction: Claudin-9 (CLDN9) is a member of the claudin protein family, a critical transmembrane protein family for tight junctions that are implemented…”
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Chronic methamphetamine exposure suppresses the striatal expression of members of multiple families of immediate early genes (IEGs) in the rat: normalization by an acute methamphetamine injection
Published in Psychopharmacologia (01-05-2011)“…Rationale Repeated injections of cocaine cause blunted responses to acute cocaine challenge-induced increases in the expression of immediate early genes…”
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Hepatitis A Virus Cellular Receptor 1 (HAVcr-1) Initiates Prostate Cancer Progression in Human Cells via Hepatocyte Growth Factor (HGF)-Induced Changes in Junctional Integrity
Published in Biomolecules (Basel, Switzerland) (21-02-2022)“…HAVcR-1 has been linked to cancer aetiology and may regulate junctional complexes, with its role in prostate cancer still unexplored. This study aims to…”
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HGF and the regulation of tight junctions in human prostate cancer cells
Published in Oncology reports (01-07-2014)“…Hepatocyte growth factor (HGF) may impact the metastasis of prostate cancer via its action on prostate stem cells or their progeny. Tight junctions (TJs) are…”
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The role of the CD44/ezrin complex in cancer metastasis
Published in Critical reviews in oncology/hematology (01-05-2003)“…CD44 is a cell adhesion molecule that was traditionally known as ‘homing receptor’. This molecule is known to interact with the ezrin family (ERM family)…”
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Design and Evaluation of Useful Bacterium-Specific PCR Primers That Amplify Genes Coding for Bacterial 16S rRNA
Published in Applied and Environmental Microbiology (01-02-1998)“…ERRATUM ( vol. 64 , p. 2333 ) Classifications Services AEM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg…”
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Observed risk of recurrent bleeding and thromboembolic disease in COVID-19 patients with gastrointestinal bleeding
Published in Endoscopy International Open (01-09-2021)“…Abstract Background and study aim COVID-19 patients are at increased risk for venous thromboembolism (VTE) requiring the use of anticoagulation…”
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