Search Results - "MARTIN, Sarah K."
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Multinucleation and Mesenchymal-to-Epithelial Transition Alleviate Resistance to Combined Cabazitaxel and Antiandrogen Therapy in Advanced Prostate Cancer
Published in Cancer research (Chicago, Ill.) (15-02-2016)“…Patients with metastatic castration-resistant prostate cancer (CRPC) frequently develop therapeutic resistance to taxane chemotherapy and antiandrogens…”
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Exploitation of the Androgen Receptor to Overcome Taxane Resistance in Advanced Prostate Cancer
Published in Advances in Cancer Research (2015)“…Prostate cancer is a tumor addicted to androgen receptor (AR) signaling, even in its castration resistant state, and recently developed antiandrogen therapies…”
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Elevated stearoyl-CoA desaturase in brains of patients with Alzheimer's disease
Published in PloS one (26-10-2011)“…The molecular bases of Alzheimer's disease (AD) remain unclear. We used a lipidomic approach to identify lipid abnormalities in the brains of subjects with AD…”
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N-terminal targeting of androgen receptor variant enhances response of castration resistant prostate cancer to taxane chemotherapy
Published in Molecular oncology (01-03-2015)“…Taxane-based chemotherapy is an effective treatment for castration-resistant-prostate cancer (CRPC) via stabilization of microtubules. Previous studies…”
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Early Jurassic Coleopterans from the Mintaja Insect Locality, Western Australia
Published in Acta geologica Sinica (Beijing) (01-08-2010)“…Beetles (Coleoptera) are the most common insects recovered from the Lower Jurassic Mintaja insect locality of Western Australia, with over half of the fossils…”
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Gene fusions find an ERG-way to tumor inflammation
Published in Cancer biology & therapy (15-02-2011)“…Commentary to: ERG oncogene modulates prostaglandin signaling in prostate cancer cells Ahmed A. Mohamed, Shyh-Han Tan, Chen Sun, Syed Shaheduzzaman, Ying Hu,…”
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Cofilin Drives Cell-Invasive and Metastatic Responses to TGF-β in Prostate Cancer
Published in Cancer research (Chicago, Ill.) (15-04-2014)“…Cofilin (CFL) is an F-actin-severing protein required for the cytoskeleton reorganization and filopodia formation, which drives cell migration. CFL binding and…”
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Identifying the powers, players, and emotions associated with REDD+ implementation: The case of Guyana’s LCDS
Published in Ambio (01-06-2020)“…REDD+ remains a critical tool for dealing with increasing levels of atmospheric carbon dioxide. Like other global-level initiatives, REDD+ has strong…”
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Early Triassic (early Olenekian) life in the interior of East Gondwana: mixed marine–terrestrial biota from the Kockatea Shale, Western Australia
Published in Palaeogeography, palaeoclimatology, palaeoecology (01-01-2015)“…A new terrestrial–marine assemblage from the lower beds of a thin outcrop section of the Kockatea Shale in the northern Perth Basin, Western Australia,…”
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Cytoskeleton targeting value in prostate cancer treatment
Published in American journal of clinical and experimental urology (01-01-2014)“…Prostate cancer is a disease that affects hundreds of thousands of men in the United States each year. In the early stages of advanced prostate cancer, the…”
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Emerging biomarkers of prostate cancer (Review)
Published in Oncology reports (01-08-2012)“…Prostate cancer progression involves activation of signaling pathways controlling cell proliferation, apoptosis, anoikis, angiogenesis and metastasis. The…”
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A first record of Cretaceous aphids (Hemiptera, Sternorrhyncha, Aphidomorpha) in Australia, from the Lower Cretaceous Koonwarra Fossil Bed, Victoria
Published in Zootaxa (08-07-2016)“…This paper describes the first species of aphid from the Lower Cretaceous Koonwarra Fossil Bed of the Gippsland Basin, southeastern Victoria, Australia. This…”
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The record of Australian Jurassic plant–arthropod interactions
Published in Gondwana research (01-04-2015)“…A survey of Australian Jurassic plant fossil assemblages reveals examples of foliar and wood damage generated by terrestrial arthropods attributed to…”
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Early Ordovician conodonts from Barnicarndy 1 stratigraphic well of the Southern Canning Basin, Western Australia
Published in Alcheringa (Sydney) (02-01-2022)“…Documented here is the systematic description of conodonts from 10 samples collected within the Nambeet Formation in Barnicarndy 1, a deep stratigraphic…”
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Valanginian–Hauterivian vegetation inferred from palynological successions from the southern Perth Basin, Western Australia
Published in Cretaceous research (01-08-2023)“…The stepwise fragmentation of Gondwana had a lasting impact on Southern Hemisphere ecosystems, but its consequences remain difficult to ascertain without…”
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A new Bothriembryon from the Nullarbor Plain, Western Australia, with insights on the age of Bothriembryon praecursor from Kangaroo Well, Northern Territory
Published in Alcheringa (Sydney) (02-04-2024)“…Fossil Bothriembryon specimens were recovered from the northwestern edges of the Nullarbor Plain, Western Australia, ∼300 km inland from the current southern…”
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Androgen Receptor Regulation by Microtubule‐targeting Chemotherapeutics in Prostate Cancer
Published in The FASEB journal (01-04-2012)“…Abstract only Prostate cancer (PCa) is the 2 nd leading cause of cancer related death in N. American males and progression to androgen independence is…”
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Early Cretaceous polar biotas of Victoria, southeastern Australia-an overview of research to date
Published in Alcheringa (Sydney) (03-04-2018)“…Poropat, S.F., Martin, S.K., Tosolini, A.-M.P., Wagstaff, B.E, Bean, L.B., Kear, B.P., Vickers-Rich, P. & Rich, T.H., May 2018. Early Cretaceous polar biotas…”
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Abstract 2567: Cabazitaxel chemotherapy targets mitotic kinesins resulting in multi-nucleation of prostate cancer cells: A novel mechanism of cross-resistance with antiandrogens in advanced CRPC
Published in Cancer research (Chicago, Ill.) (01-08-2015)“…Progression to castration-resistant prostate cancer (CRPC) is characterized by increased androgen receptor (AR) and activated AR signaling despite castrate…”
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