Search Results - "MARTIN, RAINER DE"
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Alpha-catulin contributes to drug-resistance of melanoma by activating NF-κB and AP-1
Published in PloS one (20-03-2015)“…Melanoma is the most dangerous type of skin cancer accounting for 48,000 deaths worldwide each year and an average survival rate of about 6-10 months with…”
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2
Resolution of inflammation: intracellular feedback loops in the endothelium
Published in Thrombosis and haemostasis (01-03-2007)“…Timely termination of the inflammatory reaction is equally important as its elicitation, since a persistent or exaggerated response may lead to detrimental…”
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3
Tissue factor is induced by interleukin-33 in human endothelial cells: a new link between coagulation and inflammation
Published in Scientific reports (04-05-2016)“…Tissue factor (TF) is the primary trigger of coagulation. Elevated levels of TF are found in atherosclerotic plaques and TF leads to thrombus formation when…”
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4
LC–ESI–FT–MSn Metabolite Profiling of Symphytum officinale L. Roots Leads to Isolation of Comfreyn A, an Unusual Arylnaphthalene Lignan
Published in International journal of molecular sciences (30-06-2020)“…Preparations of comfrey (Symphytum officinale L.) roots are used topically to reduce inflammation. Comfrey anti-inflammatory and analgesic properties have been…”
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5
Interleukin-33 Induces Expression of Adhesion Molecules and Inflammatory Activation in Human Endothelial Cells and in Human Atherosclerotic Plaques
Published in Arteriosclerosis, thrombosis, and vascular biology (01-09-2011)“…OBJECTIVE—Interleukin (IL)-33 is the most recently described member of the IL-1 family of cytokines and it is a ligand of the ST2 receptor. While the effects…”
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6
A Symphytum officinale Root Extract Exerts Anti-inflammatory Properties by Affecting Two Distinct Steps of NF-κB Signaling
Published in Frontiers in pharmacology (26-04-2019)“…, commonly known as comfrey, constitutes a traditional medicinal plant with a long-standing therapeutic history, and preparations thereof have been widely used…”
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7
Peucedanum ostruthium Inhibits E-Selectin and VCAM-1 Expression in Endothelial Cells through Interference with NF-κB Signaling
Published in Biomolecules (Basel, Switzerland) (21-08-2020)“…Twenty natural remedies traditionally used against different inflammatory diseases were probed for their potential to suppress the expression of the…”
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8
Alpha-Catulin Contributes to Drug-Resistance of Melanoma by Activating NF-[kappa]B and AP-1
Published in PloS one (20-03-2015)“…Melanoma is the most dangerous type of skin cancer accounting for 48,000 deaths worldwide each year and an average survival rate of about 6-10 months with…”
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9
Feed‑back loops integrating RELA, SOX18 and FAK mediate the break‑down of the lymph‑endothelial barrier that is triggered by 12(S)‑HETE
Published in International journal of oncology (01-04-2020)“…Metastatic cancer cells cross endothelial barriers and travel through the blood or lymphatic fluid to pre‑metastatic niches, leading to their colonisation. 'S'…”
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10
Levosimendan exerts anti-inflammatory effects on cardiac myocytes and endothelial cells in vitro
Published in Thrombosis and haemostasis (01-02-2015)“…Levosimendan is a positive inotropic drug for the treatment of acute decompensated heart failure (HF). Clinical trials showed that levosimendan was…”
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11
Interleukin-33 stimulates GM-CSF and M-CSF production by human endothelial cells
Published in Thrombosis and haemostasis (01-08-2016)“…Interleukin (IL)-33, a member of the IL-1 family of cytokines, is involved in various inflammatory conditions targeting amongst other cells the endothelium…”
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12
Pterocarpus santalinus Selectively Inhibits a Subset of Pro-Inflammatory Genes in Interleukin-1 Stimulated Endothelial Cells
Published in Frontiers in pharmacology (18-01-2022)“…Based on the traditional use and scientific reports on the anti-inflammatory potential of red sandalwood, i.e., the heartwood of L., we investigated its…”
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13
Novel Phosphorylation-dependent Ubiquitination of Tristetraprolin by Mitogen-activated Protein Kinase/Extracellular Signal-regulated Kinase Kinase Kinase 1 (MEKK1) and Tumor Necrosis Factor Receptor-associated Factor 2 (TRAF2)
Published in The Journal of biological chemistry (04-11-2011)“…Acute versus chronic inflammation is controlled by the accurate activation and regulation of interdependent signaling cascades. TNF-receptor 1 engagement…”
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14
A Biochemometric Approach for the Identification of In Vitro Anti-Inflammatory Constituents in Masterwort
Published in Biomolecules (Basel, Switzerland) (28-04-2020)“…(L.) Koch, commonly known as masterwort, has a longstanding history as herbal remedy in the Alpine region of Austria, where the roots and rhizomes are…”
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15
Polyubiquitinated Tristetraprolin Protects from TNF-induced, Caspase-mediated Apoptosis
Published in The Journal of biological chemistry (05-09-2014)“…Binding of TNF to its receptor (TNFR1) elicits the spatiotemporal assembly of two signaling complexes that coordinate the balance between cell survival and…”
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16
Interaction of the TNFR-receptor associated factor TRAF1 with I-kappa B kinase-2 and TRAF2 indicates a regulatory function for NF-kappa B signaling
Published in PloS one (13-09-2010)“…I-kappa B kinase 2 (IKK2 or IKK-beta) is one of the most crucial signaling kinases for activation of NF-kappa B, a transcription factor that is important for…”
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17
The Transcription Factor NF-κB and the Regulation of Vascular Cell Function
Published in Arteriosclerosis, thrombosis, and vascular biology (01-11-2000)“…A variety of pathophysiological situations that affect cells of the vasculature, including endothelial and smooth muscle cells, leads to the expression of…”
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The transcription factor SOX18 regulates the expression of matrix metalloproteinase 7 and guidance molecules in human endothelial cells
Published in PloS one (23-01-2012)“…Mutations in the transcription factor SOX18 are responsible for specific cardiovascular defects in humans and mice. In order to gain insight into the molecular…”
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19
Thrombin induces the expression of oncostatin M via AP-1 activation in human macrophages: a link between coagulation and inflammation
Published in Blood (24-09-2009)“…Macrophages as inflammatory cells are involved in the pathogenesis of atherosclerosis that today is recognized as an inflammatory disease. Activation of…”
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20
FOXF1 Mediates Endothelial Progenitor Functions and Regulates Vascular Sprouting
Published in Frontiers in bioengineering and biotechnology (14-06-2018)“…Endothelial colony forming cells (ECFC) or late blood outgrowth endothelial cells (BOEC) have been proposed to contribute to neovascularization in humans…”
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