Search Results - "MARTIN, H. J"
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Light-switchable diazocines as potential inhibitors of testosterone-synthesizing 17β-hydroxysteroid dehydrogenase 3
Published in Chemico-biological interactions (25-02-2024)“…In patients with prostate carcinoma as well as in some other cancer types, the reduction of testosterone levels is desired because the hormone stimulates…”
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2
The role of sex and weight on rituximab clearance and serum elimination half-life in elderly patients with DLBCL
Published in Blood (05-04-2012)“…Pharmacokinetics of 8 doses of rituximab (375 mg/m2) given in combination with 2-week cyclophosphamide, hydroxydaunorubicin, vincristine, and…”
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3
Conserved function of the matriptase-prostasin proteolytic cascade during epithelial morphogenesis
Published in PLoS genetics (02-01-2019)“…Extracellular matrix (ECM) assembly and remodelling is critical during development and organ morphogenesis. Dysregulation of ECM is implicated in many…”
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Assessment of body mass-related covariates for rifampicin pharmacokinetics in healthy Caucasian volunteers
Published in European journal of clinical pharmacology (01-09-2024)“…Purpose Currently, body weight-based dosing of rifampicin is recommended. But lately, fat-free mass (FFM) was reported to be superior to body weight (BW). The…”
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Soil nutrients, enzyme activities, and bacterial communities in varied plant communities in karst rocky desertification regions in Wushan County, Southwest China
Published in Frontiers in microbiology (14-06-2023)“…Vegetation restoration has become a common practice in karst rocky desertification (KRD) areas of southwestern China. The bacteria, which have made a…”
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Diversity and above-ground biomass patterns of vascular flora induced by flooding in the drawdown area of China's Three Gorges Reservoir
Published in PloS one (27-06-2014)“…Hydrological alternation can dramatically influence riparian environments and shape riparian vegetation zonation. However, it was difficult to predict the…”
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Cohort Profile: The Hertfordshire Cohort Study
Published in International journal of epidemiology (01-12-2005)Get full text
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ACE2-Independent Interaction of SARS-CoV-2 Spike Protein with Human Epithelial Cells Is Inhibited by Unfractionated Heparin
Published in Cells (Basel, Switzerland) (07-06-2021)“…Coronaviruses such as SARS-CoV-2, which is responsible for COVID-19, depend on virus spike protein binding to host cell receptors to cause infection. The…”
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Paramagnetic micro-particles as a tool for rapid quantification of apixaban, dabigatran, edoxaban and rivaroxaban in human plasma by UHPLC-MS/MS
Published in Clinical chemistry and laboratory medicine (28-08-2017)“…Assessment of the anticoagulant activity of direct oral anticoagulants (DOACs) is justified in special clinical situations. Here, we evaluated two independent…”
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Pharmacodynamic Monitoring of Mycophenolic Acid Therapy: Improved Liquid Chromatography–Tandem Mass Spectrometry Method for Measuring Inosin-5′-Monophosphate Dehydrogenase Activity
Published in Therapeutic drug monitoring (01-04-2020)“…Mycophenolic acid (MPA), a powerful inhibitor of lymphocyte proliferation, is widely used in transplantation medicine and as a glucocorticoid-sparing agent in…”
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Interleukin-1β Regulates CXCL8 Release and Influences Disease Outcome in Response to Streptococcus pneumoniae, Defining Intercellular Cooperation between Pulmonary Epithelial Cells and Macrophages
Published in Infection and Immunity (01-03-2012)“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Detection of systemic immunosuppressants in autologous serum eye drops (ASED) in patients with severe chronic ocular graft versus host disease
Published in Graefe's archive for clinical and experimental ophthalmology (01-01-2021)“…Purpose Chronic graft versus host disease is a major consequence after allogeneic stem cell transplantation (allo-SCT) and has great impact on patients’…”
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On Hilbert algebras generated by the order
Published in Archive for mathematical logic (01-02-2022)“…In this paper we study the variety of order Hilbert algebras, which is the equivalent algebraic semantics of the order implicational calculus of Bull (J Symb…”
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Reliable and Easy-To-Use Liquid Chromatography-Tandem Mass Spectrometry Assay for Quantification of Olorofim (F901318), a Novel Antifungal Drug, in Human Plasma and Serum
Published in Antimicrobial agents and chemotherapy (01-11-2018)“…A fast and easy-to-use liquid chromatography-tandem mass spectrometry (LC-MS/MS) method for the determination and quantification of a novel antifungal drug,…”
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Glycyrrhizic Acid Prevents Paclitaxel-Induced Neuropathy via Inhibition of OATP-Mediated Neuronal Uptake
Published in Cells (Basel, Switzerland) (25-04-2023)“…Peripheral neuropathy is a common side effect of cancer treatment with paclitaxel. The mechanisms by which paclitaxel is transported into neurons, which are…”
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Reliable and Easy-To-Use Liquid Chromatography-Tandem Mass Spectrometry Method for Simultaneous Analysis of Fluconazole, Isavuconazole, Itraconazole, Hydroxy-Itraconazole, Posaconazole, and Voriconazole in Human Plasma and Serum
Published in Therapeutic drug monitoring (01-10-2017)“…A fast and easy-to-use liquid chromatography-tandem mass spectrometry method for the determination and quantification of 6 triazoles [fluconazole (FLZ),…”
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Expression profiles of human 11β-hydroxysteroid dehydrogenases type 1 and type 2 in inflammatory bowel diseases
Published in Molecular and cellular endocrinology (25-03-2009)“…Inflammatory bowel diseases such as Crohn's disease (CD) and ulcerative colitis (UC) are characterized by an increase in pro-inflammatory cytokines. On the…”
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A Semi-Mechanistic Population Pharmacokinetic Model of Noscapine in Healthy Subjects Considering Hepatic First-Pass Extraction and CYP2C9 Genotypes
Published in Drugs in R&D (01-06-2024)“…Introduction Noscapine is a commonly used cough suppressant, with ongoing research on its anti-inflammatory and anti-tumor properties. The drug has a…”
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Conservation and ecofriendly utilization of wetlands associated with the Three Gorges Reservoir
Published in Environmental science and pollution research international (01-10-2013)“…The Three Gorges Dam on the Yangtze River in China has created a major reservoir in which the water level fluctuates annually by about 30 m, generating a…”
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Remifentanil Degradation in Umbilical Cord Blood of Preterm Infants
Published in Anesthesiology (Philadelphia) (01-03-2011)“…No pharmacokinetic data about remifentanil in preterm infants exist, although remifentanil is increasingly used in this especially vulnerable subgroup of…”
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