Search Results - "MARTIN, Claudio M"

Pharmacological and non-pharmacological interventions to prevent delirium in critically ill patients: a systematic review and network meta-analysis by Burry, Lisa D., Cheng, Wei, Williamson, David R., Adhikari, Neill K., Egerod, Ingrid, Kanji, Salmaan, Martin, Claudio M., Hutton, Brian, Rose, Louise

“…Purpose To compare the effects of prevention interventions on delirium occurrence in critically ill adults. Methods MEDLINE, Embase, PsychINFO, CINAHL, Web of…”
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Is access to intensive care equitable? by Martin, Claudio M

“…In a secondary analysis of a prospective cohort study, black adults were less likely than white adults to be admitted to a coronary care unit (CCU) and had…”
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Prevalent diabetes and long-term cardiovascular outcomes in adult sepsis survivors: a population-based cohort study by Angriman, Federico, Lawler, Patrick R, Shah, Baiju R, Martin, Claudio M, Scales, Damon C

“…Sepsis survivors are at elevated risk for cardiovascular disease during long-term follow-up. Whether diabetes influences cardiovascular risk after sepsis…”
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Cardiac fibroblasts contribute to myocardial dysfunction in mice with sepsis: the role of NLRP3 inflammasome activation by Zhang, Wenbo, Xu, Xuemei, Kao, Raymond, Mele, Tina, Kvietys, Peter, Martin, Claudio M, Rui, Tao

“…Myocardial contractile dysfunction in sepsis is associated with the increased morbidity and mortality. Although the underlying mechanisms of the cardiac…”
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Early mobilization in the critical care unit: A review of adult and pediatric literature by Cameron, Saoirse, MA, Ball, Ian, MD, MSc, Cepinskas, Gediminas, DVM, PhD, Choong, Karen, MB, BCh, MSc, Doherty, Timothy J., MD, PhD, Ellis, Christopher G., PhD, Martin, Claudio M., MD, MSc, Mele, Tina S., MD, PhD, Sharpe, Michael, MD, Shoemaker, J. Kevin, PhD, Fraser, Douglas D., MD, PhD

“…Abstract Early mobilization of critically ill patients is beneficial, suggesting that it should be incorporated into daily clinical practice. Early passive,…”
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Therapeutic Potential of Annexins in Sepsis and COVID-19 by Mui, Louise, Martin, Claudio M., Tschirhart, Brent J., Feng, Qingping

“…Sepsis is a continuing problem in modern healthcare, with a relatively high prevalence, and a significant mortality rate worldwide. Currently, no specific…”
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Gender differences in career satisfaction, moral distress, and incivility: a national, cross-sectional survey of Canadian critical care physicians by Burns, Karen E. A., Fox-Robichaud, Alison, Lorens, Edmund, Martin, Claudio M.

“…Purpose In a national cross-sectional survey, we aimed to i) characterize work profile, workload, and income, ii) evaluate work satisfaction, work-life…”
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Metabolomics Profiling of Critically Ill Coronavirus Disease 2019 Patients: Identification of Diagnostic and Prognostic Biomarkers by Fraser, Douglas D, Slessarev, Marat, Martin, Claudio M, Daley, Mark, Patel, Maitray A, Miller, Michael R, Patterson, Eric K, O'Gorman, David B, Gill, Sean E, Wishart, David S, Mandal, Rupasri, Cepinskas, Gediminas

“…Coronavirus disease 2019 continues to spread rapidly with high mortality. We performed metabolomics profiling of critically ill coronavirus disease 2019…”
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Pharmacokinetics of recombinant human annexin A5 (SY-005) in patients with severe COVID-19 by Tschirhart, Brent J, Lu, Xiangru, Mokale Kognou, Aristide Laurel, Martin, Claudio M, Slessarev, Marat, Fraser, Douglas D, Leligdowicz, Aleksandra, Urquhart, Bradley, Feng, Qingping

“…Annexin A5 is a phosphatidylserine binding protein with anti-inflammatory, anticoagulant and anti-apoptotic properties. Preclinical studies have shown that…”
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The Effect of Inadequate Initial Empiric Antimicrobial Treatment on Mortality in Critically Ill Patients with Bloodstream Infections: A Multi-Centre Retrospective Cohort Study by Savage, Rachel D, Fowler, Robert A, Rishu, Asgar H, Bagshaw, Sean M, Cook, Deborah, Dodek, Peter, Hall, Richard, Kumar, Anand, Lamontagne, François, Lauzier, François, Marshall, John, Martin, Claudio M, McIntyre, Lauralyn, Muscedere, John, Reynolds, Steven, Stelfox, Henry T, Daneman, Nick

“…Hospital mortality rates are elevated in critically ill patients with bloodstream infections. Given that mortality may be even higher if appropriate treatment…”
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Perceived potentially inappropriate treatment in the PICU: frequency, contributing factors and the distress it triggers by Sarpal, Amrita, Miller, Michael R, Martin, Claudio M, Sibbald, Robert W, Speechley, Kathy N

“…Potentially inappropriate treatment in critically ill adults is associated with healthcare provider distress and burnout. Knowledge regarding perceived…”
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Sex-and age-based differences in the delivery and outcomes of critical care by Fowler, Robert A, Sabur, Natasha, Li, Ping, Juurlink, David N, Pinto, Ruxandra, Hladunewich, Michelle A, Adhikari, Neill K J, Sibbald, William J, Martin, Claudio M

“…Previous studies have suggested that a patient's sex may influence the provision and outcomes of critical care. Our objective was to determine whether sex and…”
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Epitope-specific antibody responses differentiate COVID-19 outcomes and variants of concern by Voss, Courtney, Esmail, Sally, Liu, Xuguang, Knauer, Michael J, Ackloo, Suzanne, Kaneko, Tomonori, Lowes, Lori, Stogios, Peter, Seitova, Almagul, Hutchinson, Ashley, Yusifov, Farhad, Skarina, Tatiana, Evdokimova, Elena, Loppnau, Peter, Ghiabi, Pegah, Haijan, Taraneh, Zhong, Shanshan, Abdoh, Husam, Hedley, Benjamin D, Bhayana, Vipin, Martin, Claudio M, Slessarev, Marat, Chin-Yee, Benjamin, Fraser, Douglas D, Chin-Yee, Ian, Li, Shawn Sc

“…BACKGROUNDThe role of humoral immunity in COVID-19 is not fully understood, owing, in large part, to the complexity of antibodies produced in response to the…”
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7 versus 14 days of antibiotic treatment for critically ill patients with bloodstream infection: a pilot randomized clinical trial by Daneman, Nick, Rishu, Asgar H, Pinto, Ruxandra, Aslanian, Pierre, Bagshaw, Sean M, Carignan, Alex, Charbonney, Emmanuel, Coburn, Bryan, Cook, Deborah J, Detsky, Michael E, Dodek, Peter, Hall, Richard, Kumar, Anand, Lamontagne, Francois, Lauzier, Francois, Marshall, John C, Martin, Claudio M, McIntyre, Lauralyn, Muscedere, John, Reynolds, Steven, Sligl, Wendy, Stelfox, Henry T, Wilcox, M Elizabeth, Fowler, Robert A

“…Shorter-duration antibiotic treatment is sufficient for a range of bacterial infections, but has not been adequately studied for bloodstream infections. Our…”
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Preexisting Diabetes Mellitus and All-Cause Mortality in Adult Patients With Sepsis: A Population-Based Cohort Study by Angriman, Federico, Saoraya, Jutamas, Lawler, Patrick R, Shah, Baiju R, Martin, Claudio M, Scales, Damon C

“…We assessed the association of preexisting diabetes mellitus with all-cause mortality and organ support receipt in adult patients with sepsis. Population-based…”
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Critically Ill COVID-19 Patients Exhibit Anti-SARS-CoV-2 Serological Responses by Fraser, Douglas D, Cepinskas, Gediminas, Slessarev, Marat, Martin, Claudio M, Daley, Mark, Patel, Maitray A, Miller, Michael R, Patterson, Eric K, O'Gorman, David B, Gill, Sean E, Higgins, Ian, John, Julius P P, Melo, Christopher, Nini, Lylia, Wang, Xiaoqin, Zeidler, Johannes, Cruz-Aguado, Jorge A

“…Coronavirus disease 2019 (COVID-19), caused by SARS-CoV-2, is a global health care emergency. Anti-SARS-CoV-2 serological profiling of critically ill COVID-19…”
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Annexin A5 in Patients With Severe COVID-19 Disease: A Single-Center, Randomized, Double-Blind, Placebo-Controlled Feasibility Trial by Martin, Claudio M., Slessarev, Marat, Campbell, Eileen, Basmaji, John, Ball, Ian, Fraser, Douglas D., Leligdowicz, Aleksandra, Mele, Tina, Priestap, Fran, Tschirhart, Brent J., Bentall, Tracey, Lu, Xiangru, Feng, Qingping

“…OBJECTIVESTo evaluate the study design and feasibility of drug administration and safety in a randomized clinical trial of recombinant human annexin A5…”
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Quality Improvement in Critical Care: Selection and Development of Quality Indicators by Chrusch, Carla A., Project, The Quality Improvement in Critical Care, Martin, Claudio M.

“…Background. Caring for critically ill patients is complex and resource intensive. An approach to monitor and compare the function of different intensive care…”
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Comparison of risk-adjusted cumulative quality control charts compared with standardized mortality ratios in critical care by Martin, Claudio M., Priestap, Fran, Kao, Raymond

“…The optimal method for monitoring intensive care unit (ICU) performance is unknown. We sought to compare process control charts using standardized mortality…”
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A prospective determination of the incidence of perceived inappropriate care in critically ill patients by Singal, Rohit K, Sibbald, Robert, Morgan, Brenda, Quinlan, Mel, Parry, Neil, Radford, Michael, Martin, Claudio M

“…Health care providers' perceptions regarding appropriateness in end-of-life treatments have been widely studied. While nurses and physicians believe that…”
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