Search Results - "MARSHALL, John F"

A framework for the development of effective anti-metastatic agents by Anderson, Robin L., Balasas, Theo, Callaghan, Juliana, Coombes, R. Charles, Evans, Jeff, Hall, Jacqueline A., Kinrade, Sally, Jones, David, Jones, Paul S., Jones, Rob, Marshall, John F., Panico, Maria Beatrice, Shaw, Jacqui A., Steeg, Patricia S., Sullivan, Mark, Tong, Warwick, Westwell, Andrew D., Ritchie, James W. A.

“…Most cancer-related deaths are a result of metastasis, and thus the importance of this process as a target of therapy cannot be understated. By asking ‘how can…”
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Stromal features are predictive of disease mortality in oral cancer patients by Marsh, Daniel, Suchak, Krishna, Moutasim, Karwan A, Vallath, Sabarinath, Hopper, Colin, Jerjes, Waseem, Upile, Tahwinder, Kalavrezos, Nicholas, Violette, Shelia M, Weinreb, Paul H, Chester, Kerry A, Chana, Jagdeep S, Marshall, John F, Hart, Ian R, Hackshaw, Allan K, Piper, Kim, Thomas, Gareth J

“…Worldwide, approximately 405 000 cases of oral cancer (OSCC) are diagnosed each year, with a rising incidence in many countries. Despite advances in surgery…”
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Prevalence, survival analysis and multimorbidity of chronic diseases in the general veterinarian-attended horse population of the UK by Welsh, Claire E., Duz, Marco, Parkin, Timothy D.H., Marshall, John F.

“…The average age of the global human population is increasing, leading to increased interest in the effects of chronic disease and multimorbidity on health…”
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Synthesis and Systematic Study on the Effect of Different PEG Units on Stability of PEGylated, Integrin-αvβ6-Specific A20FMDV2 Analogues in Rat Serum and Human Plasma by Hung, Kuo-Yuan, Kowalczyk, Renata, Desai, Ami, Brimble, Margaret A, Marshall, John F, Harris, Paul W R

“…A20FMDV2 is a 20-mer peptide that exhibits high selectivity and affinity for the tumour-related αvβ6 integrin that can compete with extracellular ligands for…”
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Long-term adaptation following influenza A virus host shifts results in increased within-host viral fitness due to higher replication rates, broader dissemination within the respiratory epithelium and reduced tissue damage by Amat, Julien A R, Patton, Veronica, Chauché, Caroline, Goldfarb, Daniel, Crispell, Joanna, Gu, Quan, Coburn, Alice M, Gonzalez, Gaelle, Mair, Daniel, Tong, Lily, Martinez-Sobrido, Luis, Marshall, John F, Marchesi, Francesco, Murcia, Pablo R

“…The mechanisms and consequences of genome evolution on viral fitness following host shifts are poorly understood. In addition, viral fitness -the ability of an…”
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Rigidity sensing and adaptation through regulation of integrin types by Elosegui-Artola, Alberto, Bazellières, Elsa, Allen, Michael D., Andreu, Ion, Oria, Roger, Sunyer, Raimon, Gomm, Jennifer J., Marshall, John F., Jones, J. Louise, Trepat, Xavier, Roca-Cusachs, Pere

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Integrin trafficking and its role in cancer metastasis by Ramsay, Alan G, Marshall, John F, Hart, Ian R

“…Enhanced levels of expression of certain integrins, and a consequent increase in specific integrin signals, have been linked to cancer cell progression…”
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PHLDA1 Mediates Drug Resistance in Receptor Tyrosine Kinase-Driven Cancer by Fearon, Abbie E., Carter, Edward P., Clayton, Natasha S., Wilkes, Edmund H., Baker, Ann-Marie, Kapitonova, Ekaterina, Bakhouche, Bakhouche A., Tanner, Yasmine, Wang, Jun, Gadaleta, Emanuela, Chelala, Claude, Moore, Kate M., Marshall, John F., Chupin, Juliette, Schmid, Peter, Jones, J. Louise, Lockley, Michelle, Cutillas, Pedro R., Grose, Richard P.

“…Development of resistance causes failure of drugs targeting receptor tyrosine kinase (RTK) networks and represents a critical challenge for precision medicine…”
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Reversal-Specific Learning Impairments After a Binge Regimen of Methamphetamine in Rats: Possible Involvement of Striatal Dopamine by IZQUIERDO, Alicia, BELCHER, Annabelle M, SCOTT, Lori, CAZARES, Victor A, CHEN, Jack, O'DELL, Steven J, MALVAEZ, Melissa, WU, Tiffany, MARSHALL, John F

“…A growing body of evidence indicates that protracted use of methamphetamine (mAMPH) causes long-term impairments in cognitive function in humans. Aside from…”
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Running wheel exercise ameliorates methamphetamine-induced damage to dopamine and serotonin terminals by O'dell, Steven J., Galvez, Bryan A., Ball, Alexander J., Marshall, John F.

“…Repeated administration of methamphetamine (mAMPH) to rodents in a single‐day “binge” produces long‐lasting damage to dopaminergic and serotonergic terminals…”
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Absence of adaptive evolution is the main barrier against influenza emergence in horses in Asia despite frequent virus interspecies transmission from wild birds by Zhu, Henan, Damdinjav, Batchuluun, Gonzalez, Gaelle, Patrono, Livia Victoria, Ramirez-Mendoza, Humberto, Amat, Julien A R, Crispell, Joanna, Parr, Yasmin Amy, Hammond, Toni-Ann, Shiilegdamba, Enkhtuvshin, Leung, Y H Connie, Peiris, Malik, Marshall, John F, Hughes, Joseph, Gilbert, Martin, Murcia, Pablo R

“…Virus ecology and evolution play a central role in disease emergence. However, their relative roles will vary depending on the viruses and ecosystems involved…”
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Methamphetamine Influences on Recognition Memory: Comparison of Escalating and Single-Day Dosing Regimens by BELCHER, Annabelle M, FEINSTEIN, Erin M, O'DELL, Steven J, MARSHALL, John F

“…Methamphetamine (mAMPH) is an addictive drug that produces memory and recall impairments in humans. Animals subjected to a binge mAMPH dosing regimen that…”
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Betel-derived alkaloid up-regulates keratinocyte alphavbeta6 integrin expression and promotes oral submucous fibrosis by Moutasim, Karwan A, Jenei, Veronika, Sapienza, Karen, Marsh, Daniel, Weinreb, Paul H, Violette, Shelia M, Lewis, Mark P, Marshall, John F, Fortune, Farida, Tilakaratne, Waninayaka M, Hart, Ian R, Thomas, Gareth J

“…Oral submucous fibrosis (OSF) is a premalignant, fibrosing disorder of the mouth, pharynx, and oesophagus, with a malignant transformation rate of 7–13%. OSF…”
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Mechanostimulation of breast myoepithelial cells induces functional changes associated with DCIS progression to invasion by Hayward, Mary-Kate, Allen, Michael D., Gomm, Jennifer J., Goulding, Iain, Thompson, Clare L., Knight, Martin M., Marshall, John F., Jones, J. Louise

“…Women with ductal carcinoma in situ (DCIS) have an increased risk of progression to invasive breast cancer. Although not all women with DCIS will progress to…”
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The role of integrins in TGFβ activation in the tumour stroma by Khan, Zareen, Marshall, John F.

“…TGFβ1 is the most pleiotropic of all known cytokines and thus, to avoid uncontrolled TGFβ-activated processes, its activity is tightly regulated. Studies in…”
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Striatal dopamine D1 and D2 receptors: Widespread influences on methamphetamine-induced dopamine and serotonin neurotoxicity by Gross, Noah B., Duncker, Patrick C., Marshall, John F.

“…Methamphetamine (mAMPH) is an addictive psychostimulant drug that releases monoamines through nonexocytotic mechanisms. In animals, binge mAMPH dosing regimens…”
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Ligand-bound integrin αvβ6 internalisation and trafficking by Meecham, Amelia, Cutmore, Lauren C, Protopapa, Pantelitsa, Rigby, Lauren G, Marshall, John F

“…The integrin αvβ6 is expressed at low levels in most normal healthy tissue but is very often upregulated in a disease context including cancer and fibrosis…”
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Preindustrial to Modern Interdecadal Variability in Coral Reef pH by Pelejero, Carles, Calvo, Eva, McCulloch, Malcolm T, Marshall, John F, Gagan, Michael K, Lough, Janice M, Opdyke, Bradley N

“…The oceans are becoming more acidic due to absorption of anthropogenic carbon dioxide from the atmosphere. The impact of ocean acidification on marine…”
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High-throughput in vivo screening of targeted molecular imaging agents by Gagnon, M. Karen J, Hausner, Sven H, Marik, Jan, Abbey, Craig K, Marshall, John F, Sutcliffe, Julie L

“…The rapid development and translation of targeted molecular imaging agents from bench to bedside is currently a slow process, with a clear bottleneck between…”
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TGFβ-mediated MMP13 secretion drives myoepithelial cell dependent breast cancer progression by Gibson, Shayin V., Tomas Bort, Elena, Rodríguez-Fernández, Lucía, Allen, Michael D., Gomm, Jennifer J., Goulding, Iain, auf dem Keller, Ulrich, Agnoletto, Andrea, Brisken, Cathrin, Peck, Barrie, Cameron, Angus J., Marshall, John F., Jones, J. Louise, Carter, Edward P., Grose, Richard P.

“…Ductal carcinoma in situ (DCIS) is a non-obligate precursor of invasive breast cancer. Virtually all women with DCIS are treated, despite evidence suggesting…”
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