Search Results - "MARSH, ADAM G."

Epigenetic machine learning: utilizing DNA methylation patterns to predict spastic cerebral palsy by Crowgey, Erin L, Marsh, Adam G, Robinson, Karyn G, Yeager, Stephanie K, Akins, Robert E

“…Spastic cerebral palsy (CP) is a leading cause of physical disability. Most people with spastic CP are born with it, but early diagnosis is challenging, and no…”
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DNA methylation and temperature stress in an Antarctic polychaete, Spiophanes tcherniai by Marsh, Adam G, Pasqualone, Annamarie A

“…Epigenetic modifications of DNA and histones are a primary mechanism by which gene expression activities may be modified in response to environmental stimuli…”
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Distribution of CpG Motifs in Upstream Gene Domains in a Reef Coral and Sea Anemone: Implications for Epigenetics in Cnidarians by Marsh, Adam G, Hoadley, Kenneth D, Warner, Mark E

“…Coral reefs are under assault from stressors including global warming, ocean acidification, and urbanization. Knowing how these factors impact the future fate…”
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Epigenetic DNA Methylation Profiling with MSRE: A Quantitative NGS Approach Using a Parkinson's Disease Test Case by Marsh, Adam G, Cottrell, Matthew T, Goldman, Morton F

“…Epigenetics is a rapidly developing field focused on deciphering chemical fingerprints that accumulate on human genomes over time. As the nascent idea of…”
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Protein languages differ depending on microorganism lifestyle by Grzymski, Joseph J, Marsh, Adam G

“…Few quantitative measures of genome architecture or organization exist to support assumptions of differences between microorganisms that are broadly defined as…”
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Larval dispersal potential of the tubeworm Riftia pachyptila at deep-sea hydrothermal vents by Young, Craig M, Marsh, Adam G, Manahan, Donal T, Mullineaux, Lauren S

“…Hydrothermal vents are ephemeral because of frequent volcanic and tectonic activities associated with crust formation. Although the larvae of hydrothermal vent…”
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Functional Approach to Transcriptome Profiling: Linking Gene Expression Patterns to Metabolites that Matter by Hoover, Cindi A, Slattery, Marc, Marsh, Adam G

“…Secondary metabolites or natural products have been isolated from many marine organisms. These metabolites often have important bioactive functions; however,…”
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Profiling Transcriptome Complexity and Secondary Metabolite Synthesis in a Benthic Soft Coral, Sinularia polydactyla by Hoover, Cindi A, Slattery, Marc, Marsh, Adam G

“…Sinularia polydactyla, an abundant Indo-Pacific soft coral species, exhibits biochemical phenotypic plasticity, prompting investigations into differences in…”
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Partitioning of Respiration in an Animal-Algal Symbiosis: Implications for Different Aerobic Capacity between Symbiodinium spp by Hawkins, Thomas D, Hagemeyer, Julia C G, Hoadley, Kenneth D, Marsh, Adam G, Warner, Mark E

“…Cnidarian-dinoflagellate symbioses are ecologically important and the subject of much investigation. However, our understanding of critical aspects of…”
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Machine learning classifier approaches for predicting response to RTK-type-III inhibitors demonstrate high accuracy using transcriptomic signatures and ex vivo data by Ferrato, Mauricio H, Marsh, Adam G, Franke, Karl R, Huang, Benjamin J, Kolb, E Anders, DeRyckere, Deborah, Grahm, Douglas K, Chandrasekaran, Sunita, Crowgey, Erin L

“…Abstract Motivation The application of machine learning (ML) techniques in the medical field has demonstrated both successes and challenges in the precision…”
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DNA Methylation Analysis Reveals Distinct Patterns in Satellite Cell-Derived Myogenic Progenitor Cells of Subjects with Spastic Cerebral Palsy by Robinson, Karyn G, Marsh, Adam G, Lee, Stephanie K, Hicks, Jonathan, Romero, Brigette, Batish, Mona, Crowgey, Erin L, Shrader, M Wade, Akins, Robert E

“…Spastic type cerebral palsy (CP) is a complex neuromuscular disorder that involves altered skeletal muscle microanatomy and growth, but little is known about…”
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Physiological bases of genetically determined variation in growth of marine invertebrate larvae: A study of growth heterosis in the bivalve Crassostrea gigas by Pace, Douglas A., Marsh, Adam G., Leong, Patrick K., Green, Allison J., Hedgecock, Dennis, Manahan, Donal T.

“…Many species of marine animals have larval stages whose rates of growth in the plankton are regulated by complex combinations of biological and environmental…”
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RNA-Seq reveals infection-related global gene changes in Phytophthora phaseoli, the causal agent of lima bean downy mildew by KUNJETI, SRIDHARA G., EVANS, THOMAS A., MARSH, ADAM G., GREGORY, NANCY F., KUNJETI, SARITHA, MEYERS, BLAKE C., KALAVACHARLA, VENUGOPAL S., DONOFRIO, NICOLE M.

“…SUMMARY Lima bean is an important vegetable processing crop to the mid‐Atlantic USA and is highly susceptible to the oomycete pathogen Phytophthora phaseoli,…”
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Effects of Ag nanoparticles on survival and oxygen consumption of zebra fish embryos, Danio rerio by Cowart, Dominique A, Guida, Stephanie M, Shah, S. Ismat, Marsh, Adam G

“…Ultrafine silver (Ag) particles, defined as having one dimension in 1–100 nanometer (nm) size range, pose a unique threat to aquatic ecosystems due to their…”
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Salinity sensitivity of early embryos of the Antarctic sea urchin, Sterechinus neumayeri by Cowart, Dominique A, Ulrich, Paul N, Miller, Douglas C, Marsh, Adam G

“…Embryos and larvae of the Antarctic sea urchin, Sterechinus neumayeri, have received considerable experimental attention assessing impacts of low temperature…”
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The Role of Nutrition in Regulating the Population Dynamics of Opportunistic, Surface Deposit Feeders in a Mesohaline Community by Marsh, Adam G., Tenore, Kenneth R.

“…The role of food resources in regulating seasonal population dynamics was determined in a benthic community typical of mesohaline regions in Chesapeake Bay…”
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The dynamic response of optical oxygen sensors and voltammetric electrodes to temporal changes in dissolved oxygen concentrations by Glazer, Brian T., Marsh, Adam G., Stierhoff, Kevin, Luther, George W.

“…Accurately measuring dissolved oxygen concentrations in fresh and salt water environments has long been an interdisciplinary priority. Many methodologies…”
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Transcriptome and Metabolite Responses to Predation in a South Pacific Soft Coral by Hoover, Cindi A., Slattery, Marc, Targett, Nancy M., Marsh, Adam G.

“…Sinularia polydactyla, a dioecious, abundant soft coral in the South Pacific, exhibits biochemical phenotypic plasticity in secondary metabolite production in…”
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High Macromolecular Synthesis with Low Metabolic Cost in Antarctic Sea Urchin Embryos by Marsh, Adam G., Maxson, Robert E., Manahan, Donal T.

“…Assessing the energy costs of development in extreme environments is important for understanding how organisms can exist at the margins of the biosphere…”
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Microtiter plate, optode respirometry, and inter-individual variance in metabolic rates among nauplii of Artemia sp by SZELA, Tracy L, MARSH, Adam G

“…Understanding the potential metabolic lifespan of a cohort of marine invertebrate embryos or larvae requires not just precise measurements of respiration…”
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