Search Results - "MARRERO, Pedro F"

Activating transcription factor 4-dependent induction of FGF21 during amino acid deprivation by De Sousa-Coelho, Ana Luísa, Marrero, Pedro F, Haro, Diego

“…Nutrient deprivation or starvation frequently correlates with amino acid limitation. Amino acid starvation initiates a signal transduction cascade starting…”
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Nutritional Regulation of Gene Expression: Carbohydrate-, Fat- and Amino Acid-Dependent Modulation of Transcriptional Activity by Haro, Diego, Marrero, Pedro F, Relat, Joana

“…The ability to detect changes in nutrient levels and generate an adequate response to these changes is essential for the proper functioning of living…”
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Metabolic Impact of Flavonoids Consumption in Obesity: From Central to Peripheral by Sandoval, Viviana, Sanz-Lamora, Hèctor, Arias, Giselle, Marrero, Pedro F, Haro, Diego, Relat, Joana

“…The prevention and treatment of obesity is primary based on the follow-up of a healthy lifestyle, which includes a healthy diet with an important presence of…”
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Fibroblast Growth Factor 21 and the Adaptive Response to Nutritional Challenges by Martínez-Garza, Úrsula, Torres-Oteros, Daniel, Yarritu-Gallego, Alex, Marrero, Pedro F, Haro, Diego, Relat, Joana

“…The Fibroblast Growth Factor 21 (FGF21) is considered an attractive therapeutic target for obesity and obesity-related disorders due to its beneficial effects…”
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Different fatty acid metabolism effects of (-)-epigallocatechin-3-gallate and C75 in adenocarcinoma lung cancer by Relat, Joana, Blancafort, Adriana, Oliveras, Glòria, Cufí, Sílvia, Haro, Diego, Marrero, Pedro F, Puig, Teresa

“…Fatty acid synthase (FASN) is overexpressed and hyperactivated in several human carcinomas, including lung cancer. We characterize and compare the anti-cancer…”
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FGF21 mediates the lipid metabolism response to amino acid starvation by De Sousa-Coelho, Ana Luísa, Relat, Joana, Hondares, Elayne, Pérez-Martí, Albert, Ribas, Francesc, Villarroya, Francesc, Marrero, Pedro F., Haro, Diego

“…Lipogenic gene expression in liver is repressed in mice upon leucine deprivation. The hormone fibroblast growth factor 21 (FGF21), which is critical to the…”
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A low‐protein diet induces body weight loss and browning of subcutaneous white adipose tissue through enhanced expression of hepatic fibroblast growth factor 21 (FGF21) by Pérez‐Martí, Albert, Garcia‐Guasch, Maite, Tresserra‐Rimbau, Anna, Carrilho‐Do‐Rosário, Alexandra, Estruch, Ramon, Salas‐Salvadó, Jordi, Martínez‐González, Miguel Ángel, Lamuela‐Raventós, Rosa, Marrero, Pedro F., Haro, Diego, Relat, Joana

“…Scope Fibroblast growth factor 21 (FGF21) is considered a promising therapeutic candidate for the treatment of obesity. Since FGF21 production is regulated by…”
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Novel Inhibitors of Fatty Acid Synthase with Anticancer Activity by PUIG, Teresa, TURRADO, Carlos, LUZ LOPEZ-RODRIGUEZ, María, COLOMER, Ramon, BENHAMU, Bellinda, AGUILAR, Helena, RELAT, Joana, ORTEGA-GUTIERREZ, Silvia, CASALS, Gemma, MARRERO, Pedro F, URRUTICOECHEA, Ander, HARO, Diego

“…Purpose: Fatty acid synthase (FASN) is overexpressed in human breast carcinoma. The natural polyphenol (−)-epigallocatechin-3-gallate blocks in vitro FASN…”
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Fsp27/CIDEC is a CREB target gene induced during early fasting in liver and regulated by FA oxidation rate by Vilà-Brau, Anna, De Sousa-Coelho, Ana Luísa, Gonçalves, Joana F., Haro, Diego, Marrero, Pedro F.

“…FSP27 [cell death-inducing DFFA-like effector c (CIDEC) in humans] is a protein associated with lipid droplets that downregulates the fatty acid oxidation…”
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A Mixture of Pure, Isolated Polyphenols Worsens the Insulin Resistance and Induces Kidney and Liver Fibrosis Markers in Diet-Induced Obese Mice by Sanz-Lamora, Hèctor, Marrero, Pedro F, Haro, Diego, Relat, Joana

“…Obesity is a worldwide epidemic with severe metabolic consequences. Polyphenols are secondary metabolites in plants and the most abundant dietary antioxidants,…”
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Regulation of human class I alcohol dehydrogenases by bile acids by Langhi, Cédric, Pedraz-Cuesta, Elena, Haro, Diego, Marrero, Pedro F., Rodríguez, Joan C.

“…Class I alcohol dehydrogenases (ADH1s) are the rate-limiting enzymes for ethanol and vitamin A (retinol) metabolism in the liver. Because previous studies have…”
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Lyophilized Maqui ( Aristotelia chilensis ) Berry Induces Browning in the Subcutaneous White Adipose Tissue and Ameliorates the Insulin Resistance in High Fat Diet-Induced Obese Mice by Sandoval, Viviana, Femenias, Antoni, Martínez-Garza, Úrsula, Sanz-Lamora, Hèctor, Castagnini, Juan Manuel, Quifer-Rada, Paola, Lamuela-Raventós, Rosa Maria, Marrero, Pedro F, Haro, Diego, Relat, Joana

“…Maqui ( ) berry features a unique profile of anthocyanidins that includes high amounts of delphinidin-3-O-sambubioside-5-O-glucoside and…”
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Lyophilized Maqui ( Aristotelia chilensis ) Berry Administration Suppresses High-Fat Diet-Induced Liver Lipogenesis through the Induction of the Nuclear Corepressor SMILE by Sandoval, Viviana, Sanz-Lamora, Hèctor, Marrero, Pedro F, Relat, Joana, Haro, Diego

“…The liver is one of the first organs affected by accumulated ectopic lipids. Increased de novo lipogenesis and excessive triglyceride accumulation in the liver…”
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An Intronic Peroxisome Proliferator-activated Receptor-binding sequence Mediates Fatty Acid Induction of the Human Carnitine Palmitoyltransferase 1A by Napal, Laura, Marrero, Pedro F., Haro, Diego

“…The liver plays a central role in the response to fasting. The hormonal profile in this condition, low insulin, and high concentrations of glucagon in plasma,…”
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Ketogenic HMGCS2 Is a c-Myc Target Gene Expressed in Differentiated Cells of Human Colonic Epithelium and Down-Regulated in Colon Cancer by Camarero, Nuria, Mascaró, Cristina, Mayordomo, Cristina, Vilardell, Felip, Haro, Diego, Marrero, Pedro F

“…HMGCS2 , the gene that regulates ketone body production, is expressed in liver and several extrahepatic tissues, such as the colon. In CaCo-2 colonic…”
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Green Tea Catechin Inhibits Fatty Acid Synthase without Stimulating Carnitine Palmitoyltransferase-1 or Inducing Weight Loss in Experimental Animals by PUIG, Teresa, RELAT, Joana, MARRERO, Pedro F, HARO, Diego, BRUNET, Joan, COLOMER, Ramon

“…Background: The enzyme fatty acid synthase (FASN) is highly expressed in many human carcinomas and its inhibition is cytotoxic to human cancer cells. The use…”
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Regulation of N-Myc downstream regulated gene 2 by bile acids by Langhi, Cédric, Pedraz-Cuesta, Elena, Donate, Yolanda, Marrero, Pedro F., Haro, Diego, Rodríguez, Joan C.

“…•Bile acid CDCA induces tumor suppressor NDRG2 expression in hepatocytes.•Induction of NDRG2 by bile acids requires FXR expression.•An intronic FXR-response…”
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FOXO1 represses PPARα-Mediated induction of FGF21 gene expression by De Sousa-Coelho, Ana Luísa, Gacias, Mar, O'Neill, Brian T., Relat, Joana, Link, Wolfgang, Haro, Diego, Marrero, Pedro F.

“…Fibroblast growth factor 21 (FGF21) has emerged as a metabolic regulator that exerts potent anti-diabetic and lipid-lowering effects in animal models of…”
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Control of human carnitine palmitoyltransferase II gene transcription by peroxisome proliferator-activated receptor through a partially conserved peroxisome proliferator-responsive element by Barrero, María J, Camarero, Nuria, Marrero, Pedro F, Haro, Diego

“…The expression of several genes involved in fatty acid metabolism is regulated by peroxisome proliferator-activated receptors (PPARs). To gain more insight…”
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Human HMGCS2 Regulates Mitochondrial Fatty Acid Oxidation and FGF21 Expression in HepG2 Cell Line by Vilà-Brau, Anna, De Sousa-Coelho, Ana Luísa, Mayordomo, Cristina, Haro, Diego, Marrero, Pedro F.

“…HMGCS2 (hydroxymethylglutaryl CoA synthase 2), the gene that regulates ketone body production, is barely expressed in cultured cell lines. In this study, we…”
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