Search Results - "MARKS, Eileen"
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Iron accumulates in Huntington's disease neurons: protection by deferoxamine
Published in PloS one (11-10-2013)“…Huntington's disease (HD) is a progressive neurodegenerative disorder caused by a polyglutamine-encoding CAG expansion in the huntingtin gene. Iron accumulates…”
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Validity of plasma collection cards for ferritin assessment—A proof‐of‐concept study
Published in European journal of haematology (01-06-2020)“…Objectives Iron depletion is common around the world and among certain risk groups in developed countries. The overall purpose was to test the suitability of a…”
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Renal iron accumulation occurs in lupus nephritis and iron chelation delays the onset of albuminuria
Published in Scientific reports (09-10-2017)“…Proteins involved in iron homeostasis have been identified as biomarkers for lupus nephritis, a serious complication of systemic lupus erythematosus (SLE). We…”
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Interleukin-1β as a driver of renal NGAL production
Published in Cytokine (Philadelphia, Pa.) (01-03-2017)“…Neutrophil gelatinase-associated lipocalin (NGAL) is increasingly regarded as a biomarker of acute kidney injury, or kidney injury in general, but the stimuli…”
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Estradiol regulates AQP2 expression in the collecting duct: a novel inhibitory role for estrogen receptor α
Published in American journal of physiology. Renal physiology (15-08-2015)“…While there is evidence that sex hormones influence multiple systems involved in salt and water homeostasis, the question of whether sex hormones regulate…”
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Altered selenium status in Huntington's disease: Neuroprotection by selenite in the N171-82Q mouse model
Published in Neurobiology of disease (01-11-2014)“…Abstract Disruption of redox homeostasis is a prominent feature in the pathogenesis of Huntington's disease (HD). Selenium an essential element nutrient that…”
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Daily injection of the β2 adrenergic agonist clenbuterol improved poor muscle growth and body composition in lambs following heat stress-induced intrauterine growth restriction
Published in Frontiers in physiology (06-09-2023)“…Background: Intrauterine growth restriction ( IUGR ) is associated with reduced β2 adrenergic sensitivity, which contributes to poor postnatal muscle growth…”
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Daily Eicosapentaenoic Acid Infusion in IUGR Fetal Lambs Reduced Systemic Inflammation, Increased Muscle ADRβ2 Content, and Improved Myoblast Function and Muscle Growth
Published in Metabolites (01-06-2024)“…Intrauterine growth-restricted (IUGR) fetuses exhibit systemic inflammation that contributes to programmed deficits in myoblast function and muscle growth…”
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Daily Injection of the β2 Adrenergic Agonist Clenbuterol Improved Muscle Glucose Metabolism, Glucose-Stimulated Insulin Secretion, and Hyperlipidemia in Juvenile Lambs Following Heat-Stress-Induced Intrauterine Growth Restriction
Published in Metabolites (01-03-2024)“…Stress-induced fetal programming diminishes β2 adrenergic tone, which coincides with intrauterine growth restriction ( ) and lifelong metabolic dysfunction. We…”
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Maternofetal inflammation induced for 2 wk in late gestation reduced birth weight and impaired neonatal growth and skeletal muscle glucose metabolism in lambs
Published in Journal of animal science (01-05-2021)“…Abstract Intrauterine stress impairs growth and metabolism in the fetus and offspring. We recently found that sustained maternofetal inflammation resulted in…”
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Primary myoblasts from intrauterine growth-restricted fetal sheep exhibit intrinsic dysfunction of proliferation and differentiation that coincides with enrichment of inflammatory cytokine signaling pathways
Published in Journal of animal science (01-08-2022)“…Intrauterine growth restriction (IUGR) is linked to lifelong reductions in muscle mass due to intrinsic functional deficits in myoblasts, but the mechanisms…”
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Intermittent maternofetal oxygenation during late gestation improved birthweight, neonatal growth, body symmetry, and muscle metabolism in intrauterine growth-restricted lambs
Published in Journal of animal science (01-01-2022)“…Abstract In humans and animals, intrauterine growth restriction (IUGR) results from fetal programming responses to poor intrauterine conditions. Chronic fetal…”
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Lipoprotein(a): an independent risk factor for ischemic heart disease that is dependent on triglycerides in subjects with type 2 diabetes mellitus
Published in Lipids in health and disease (02-10-2007)“…Lipoprotein(a) is an independent risk factor for Ischaemic Heart Disease (IHD) in the general population. There are conflicting reports in the extent of its…”
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Impact of high iron intake on cognition and neurodegeneration in humans and in animal models: a systematic review
Published in Nutrition reviews (01-06-2017)“…Abstract Context: Accumulation of brain iron is linked to aging and protein-misfolding neurodegenerative diseases. High iron intake may influence important…”
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ApolipoproteinA1-75 G/A (M1-) polymorphism and lipoprotein(a); anti- vs. pro-Atherogenic properties
Published in Lipids in health and disease (06-08-2007)“…ApolipoproteinA1 (apoA1) is the major apoprotein constituent of high-density-lipoprotein(HDL). The relationship of apoA1 -75 bp(M1-) allele polymorphism with…”
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Atypical presentation of a middle age male with severe hypertriglyceridaemia: a case report
Published in Journal of medical case reports (14-07-2007)“…Severe hypertriglyceridaemia (HTG) is uncommon but most prevalent in subjects with type 2 diabetes mellitus (T2DM) and excess ethanol intake. We describe a…”
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Estrogen increases expression of aquaporin‐2 protein in the inner medullary collecting duct (1137.3)
Published in The FASEB journal (01-04-2014)“…Previous studies of sex differences in renal water handling have focused on vasopressin and the V2 receptor rather than possible differences in their…”
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Vitamin D assessment in primary care: changing patterns of testing
Published in London journal of primary care (01-01-2015)“…Background Over recent years there has been increased interest in the disease burden associated with vitamin D deficiency. This, combined with recognition that…”
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On-going lessons in fluid prescription: assessment of adherence to weight-based intravenous fluid prescribing in medical inpatients
Published in Clinical medicine (London, England) (01-10-2015)“…Letters not directly related to articles published in Clinical Medicine and presenting unpublished original data should be submitted for publication in this…”
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