Search Results - "MARIS RANUNCOLO, Stella"

Alternative and canonical NF-kB pathways DNA-binding hierarchies networks define Hodgkin lymphoma and Non-Hodgkin diffuse large B Cell lymphoma respectively by Gamboa-Cedeño, Angélica María, Castillo, Mariángeles, Xiao, Wenming, Waldmann, Thomas A., Ranuncolo, Stella Maris

“…Purpose Despite considerable evidence that supports the NF-kB role in the immune system and lymphomagenesis, it is unclear whether specific NF-kB dimers…”
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Lymphotropic Viruses EBV, KSHV and HTLV in Latin America: Epidemiology and Associated Malignancies. A Literature-Based Study by the RIAL-CYTED by Chabay, Paola, Lens, Daniela, Hassan, Rocio, Rodríguez Pinilla, Socorro María, Valvert Gamboa, Fabiola, Rivera, Iris, Huamán Garaicoa, Fuad, Ranuncolo, Stella Maris, Barrionuevo, Carlos, Morales Sánchez, Abigail, Scholl, Vanesa, De Matteo, Elena, Preciado, Ma. Victoria, Fuentes-Pananá, Ezequiel M.

“…The Epstein–Barr virus (EBV), Kaposi sarcoma herpesvirus (KSHV) and human T-lymphotropic virus (HTLV-1) are lymphomagenic viruses with region-specific induced…”
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Bcl-6 mediates the germinal center B cell phenotype and lymphomagenesis through transcriptional repression of the DNA-damage sensor ATR by Carroll, Martin, Melnick, Ari, Ranuncolo, Stella Maris, Polo, Jose M, Dierov, Jamil, Singer, Michael, Kuo, Tracy, Greally, John, Green, Roland

“…Antibody specificity and diversity is generated in B cells during germinal center maturation through clonal expansion while they undergo class-switch…”
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Apoptotic regulator BCL-2 blockade as a potential therapy in classical Hodgkin Lymphoma by Gamboa-Cedeño, Angélica María, Díaz, Mariángeles, Cristaldo, Nancy, Otero, Victoria, Schutz, Natalia, Fantl, Dorotea, Cugliari, Silvana, Zerga, Marta, Rojas-Bilbao, Erica, Jauk, Federico, García Rivello, Hernán, Nuñez, Myriam, Ranuncolo, Stella Maris

“…The challenge in classical Hodgkin Lymphoma (cHL) management is the 30–40% of refractory/relapsed cases. The aim of this work was to determine whether NIK and…”
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Specific peptide interference reveals BCL6 transcriptional and oncogenic mechanisms in B-cell lymphoma cells by Melnick, Ari, Polo, Jose M, Dell'Oso, Tania, Ranuncolo, Stella Maris, Cerchietti, Leandro, Beck, David, Da Silva, Gustavo F, Prive, Gilbert G, Licht, Jonathan D

“…The BTB/POZ transcriptional repressor and candidate oncogene BCL6 is frequently misregulated in B-cell lymphomas. The interface through which the BCL6 BTB…”
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BCL6-mediated Attenuation of DNA Damage Sensing Triggers Growth Arrest and Senescence through a p53-dependent Pathway in a Cell Context-dependent Manner by Ranuncolo, Stella Maris, Wang, Ling, Polo, Jose M., Dell’Oso, Tania, Dierov, Jamil, Gaymes, Terry J., Rassool, Feyruz, Carroll, Martin, Melnick, Ari

“…The BCL6 oncogenic transcriptional repressor is required for development of germinal center centroblasts, which undergo simultaneous genetic recombination and…”
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CD44 expression in human gliomas by Ranuncolo, Stella Maris, Ladeda, Virginia, Specterman, Sergio, Varela, Mirta, Lastiri, José, Morandi, Ana, Matos, Elena, De Kier Joffe, Elisa Bal, Puricelli, Lydia, Pallotta, María Guadalupe

“…Background and Objectives Glioma invasiveness involves the attachment of tumor cells to the brain extracellular matrix, rich in hyaluronic acid (HA). CD44, the…”
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Abstract 766: Refractory and relapsed predictive biomarkers in Hodgkin lymphoma and potential directed-therapy targets by Gamboa-Cedeño, Angélica M., Otero, Victoria, Schutz, Natalia, Fantl, Dorotea, Rivello, Hernán, Jauk-Vitali, Federico, Nuñez, Myriam, Ranuncolo, Stella Maris

“…Abstract Despite 90% stage I Hodgkin Lymphoma (HL) patients can respond to current therapy, this drops to 60% when diagnosed in late stages. Nevertheless and…”
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Abstract 4032: The alternative NF-kB pathway activity in refractory and relapsed Hodgkin lymphoma by Gamboa-Cedeño, Angélica María, castillo, Mariángeles, Otero, Victoria, Schutz, Natalia, Fantl, Dorotea, Vitali, Federico Jauk, Rivello, Hernán García, Nuñez, Myriam, Ranuncolo, Stella Maris

“…Abstract The refractory and relapsed disease is currently the challenge in Hodgkin Lymphoma (HL) treatment. There is no specific therapy but rescue…”
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BCL2 Expression Correlates with Refractory and Relapsed Classic Hodgkin Lymphoma. Its Blokeadge As a Promising Directed-Therapy by Gamboa-Cedeño, Angelica, Nancy, Cristaldo, Otero, Victoria, Schutz, Natalia Paola, Fantl, Dorotea, Silvana Cugliari, Maria, Zerga, Marta, Erica, Rojas-Bilbao, García Rivello, Hernán, Jauk, Federico, Nuñez, Myriam, Ranuncolo, Stella Maris

“…Classic Hodgkin Lymphoma (cHL) is a germinal center derived lymphoma with 8,500-9,000 new cases/year diagnosed in the US. Despite 90% stage I cHL patients can…”
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Abstract 3550: Expression of Oct-2, OCA-B, BCL6, PU.1 and IRF8 predicts prognosis in Diffuse Large B Cell Lymphoma patients by Rojas Bilbao, Erica A., Bal de Kier Joffe, Elisa D., Zerga, Marta E., Puricelli, Lydia I., Ranuncolo, Stella Maris N.

“…Abstract Diffuse Large B Cell Lymphoma (DLBCL) is the most common B cell Non Hodgkin lymphoma in adults.  While 50% of patients are cured with standard…”
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Abstract 1577: Levels of Fibroblast Growth Factor 21 (FGF21) in serum as diagnostic biomarker in patients with breast cancer by Knott, Maria Elena, Ranuncolo, Stella Maris, Nuñez, Myriam, Armanasco, Eduardo, Puricelli, Lydia Ines, De Lorenzo, Mariana Silvia

“…Abstract Epidemiological studies have suggested a close link between obesity and breast cancer. There is an immediate need to investigate the potential…”
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Abstract 431: Circulating fibroblast growth factor 21 (FGF21) as diagnostic and prognostic biomarker in renal cancer by Knott, Maria Elena, Minatta, Jose Nicolas, Roulet, Lucia, Gueglio, Guillermo, Pasik, Leonardo, Ranuncolo, Stella Maris, Nuñez, Myriam, Puricelli, Lydia Ines, De Lorenzo, Mariana Silvia

“…Abstract Clear-cell renal cell carcinoma (ccRCC), the most frequent renal parenchyma malignant neoplasm, is considered a cell metabolic disease. The finding of…”
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Plasma MMP‐9 (92 kDa‐MMP) activity is useful in the follow‐up and in the assessment of prognosis in breast cancer patients by Ranuncolo, Stella Maris, Armanasco, Eduardo, Cresta, Carlos, Bal de Kier Joffe, Elisa, Puricelli, Lydia

“…Previously we determined that plasma MMP‐9 activity was significantly elevated in breast cancer patients compared to benign mammary pathologies and healthy…”
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EGF-R and PDGF-R, but not bcl-2, overexpression predict overall survival in patients with low-grade astrocytomas by Varela, Mirta, Ranuncolo, Stella Maris, Morand, Ana, Lastiri, José, Joffé, Elisa Bal De Kier, Puricelli, Lydia Inés, Pallotta, María Guadalupe

“…Background and Objectives Therapy of malignant glioma tumors is based on histology and clinical factors. However, comparable lesions may correspond with…”
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BCL6-mediated Attenuation of DNA Damage Sensing Triggers Growth Arrest and Senescence through a p53-dependent Pathway in a Cell Context-dependent MannerS by Ranuncolo, Stella Maris, Wang, Ling, Polo, Jose M., Dell'Oso, Tania, Dierov, Jamil, Gaymes, Terry J., Rassool, Feyruz, Carroll, Martin, Melnick, Ari

“…The BCL6 oncogenic transcriptional repressor is required for development of germinal center centroblasts, which undergo simultaneous genetic recombination and…”
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The BCL6 Oncoprotein Forms Distinct Transcriptional Repression Complexes on Cohorts of Target Genes Involved in Specific Cellular Functions by Polo, Jose M., Ranuncolo, Stella Maris, Parek, Samir, Arcaya, Jose, Melnick, Ari M.

“…The BCL6 (B-Cell-Lymphoma-6) oncoprotein is required for formation of germinal centers by normal B-cells and is frequently constitutively activated in B-cell…”
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Inhibition of Tumor Progression and Paraneoplastic Syndrome Development in a Murine Lung Adenocarcinoma by Medroxyprogesterone Acetate and Indomethacin by Diament, Miriam Judith, Peluffo, Guillermo Daniel, Stillitani, Isabel, Cerchietti, Leandro Carlos, Navigante, Alfredo, Ranuncolo, Stella Maris, Klein, Slobodanka Mariana

“…Mice bearing LP07 lung adenocarcinoma present some characteristics similar to those shown in patients with several malignant diseases. LP07 tumor bearers…”
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Specific Peptide Disruption of the Bcl-6 Repression Complex Reveals Its Transcriptional Mechanism of Action in Normal and Malignant B-Cells and Is a Novel Therapeutic Approach for Diffuse Large B-Cell Lymphoma by Polo, Jose M., Dell'Oso, Tania, Ranuncolo, Stella Maris, Cerchietti, Leandro, Da Silva, Gustavo F., Prive, Gilvert G., Licht, Jonathan D., Melnick, Ari

“…The Bcl-6 transcriptional repressor is required for the establishment of germinal centers during B-cell maturation. Regulatory elements of the BCL6 gene are…”
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Author reply by Ranuncolo, Stella Maris, Puricelli, Lydia Inés, Bal de Kier Joffé, Elisa, Roffo”, “Angel H., Matos, Elena, Loria, Dora, Vilensky, Marta

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