Search Results - "MARINO, Laura"
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1
Visualizing protein breathing motions associated with aromatic ring flipping
Published in Nature (London) (24-02-2022)“…Aromatic residues cluster in the core of folded proteins, where they stabilize the structure through multiple interactions. Nuclear magnetic resonance (NMR)…”
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2
A Coarse-Grained Molecular Dynamics Approach to the Study of the Intrinsically Disordered Protein α‑Synuclein
Published in Journal of chemical information and modeling (22-04-2019)“…Intrinsically disordered proteins (IDPs) are not well described by a single 3D conformation but by an ensemble of them, which makes their structural…”
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3
Endocrine causes of nonalcoholic fatty liver disease
Published in World journal of gastroenterology : WJG (21-10-2015)“…Nonalcoholic fatty liver disease(NAFLD) is the most common cause of chronic liver disease in the industrialized world. The prevalence of NAFLD is increasing,…”
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4
Two weighted c-medoids batch SOM algorithms for dissimilarity data
Published in Information sciences (01-08-2022)“…•The paper proposes two weighted c-medoid batch SOM for dissimilarity data.•The paper extends the batch SOM with C-medoids and multi-medoids algorithms.•The…”
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Vector batch SOM algorithms for multi-view dissimilarity data
Published in Knowledge-based systems (22-12-2022)“…Multi-view data has become fairly important since large amounts of information are constantly generated from different sources. So far, most multi-view…”
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6
Mechanistic Insights in Glycation-Induced Protein Aggregation
Published in Biomacromolecules (08-09-2014)“…Protein glycation causes loss-of-function through a process that has been associated with several diabetic-related diseases. Additionally, glycation has been…”
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7
Congenital hypogonadotropic hypogonadism and constitutional delay of growth and puberty have distinct genetic architectures
Published in European journal of endocrinology (01-04-2018)“…Objective Congenital hypogonadotropic hypogonadism (CHH) and constitutional delay of growth and puberty (CDGP) represent rare and common forms of GnRH…”
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8
Surgical treatment of acromegaly according to the 2010 remission criteria: systematic review and meta-analysis
Published in Acta neurochirurgica (01-11-2016)“…Background In 2010, the Acromegaly Consensus Group revised the criteria for cure of acromegaly and thus rates of surgical remission need to be revised in light…”
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9
Personality disorders in individuals with functional seizures: a systematic review
Published in Frontiers in psychiatry (01-08-2024)“…Functional seizures (FS) are classified as conversion disorders in the DSM-5 and dissociative disorders in the ICD-11, showing a multifactorial psychopathology…”
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10
Characterization of a small tRNA‐binding protein that interacts with the archaeal proteasome complex
Published in Molecular microbiology (01-07-2022)“…The proteasome system allows the elimination of functional or structurally impaired proteins. This includes the degradation of nascent peptides. In Archaea,…”
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11
Anthracycline Cardiomyopathy Is Mediated by Depletion of the Cardiac Stem Cell Pool and Is Rescued by Restoration of Progenitor Cell Function
Published in Circulation (New York, N.Y.) (19-01-2010)“…Anthracyclines are the most effective drugs available in the treatment of neoplastic diseases; however, they have profound consequences on the structure and…”
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12
Glycation of Lysozyme by Glycolaldehyde Provides New Mechanistic Insights in Diabetes-Related Protein Aggregation
Published in ACS chemical biology (21-04-2017)“…Glycation occurs in vivo as a result of the nonenzymatic reaction of carbohydrates (and/or their autoxidation products) with proteins, DNA, or lipids. Protein…”
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13
Effects of Age and Heart Failure on Human Cardiac Stem Cell Function
Published in The American journal of pathology (01-07-2011)“…Currently, it is unknown whether defects in stem cell growth and differentiation contribute to myocardial aging and chronic heart failure (CHF), and whether a…”
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14
Combined immune checkpoint inhibitor therapy with nivolumab and ipilimumab causing acute-onset type 1 diabetes mellitus following a single administration: two case reports
Published in BMC endocrine disorders (23-12-2019)“…The use of immune checkpoint inhibitor (ICI) therapy is becoming a standard of care for several cancers. Monoclonal antibodies targeting cytotoxic T-lymphocyte…”
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15
Nitration and Glycation Diminish the α‑Synuclein Role in the Formation and Scavenging of Cu2+-Catalyzed Reactive Oxygen Species
Published in ACS chemical neuroscience (19-06-2019)“…Human α-synuclein is a small monomeric protein (140 residues) essential to maintain the function of the dopaminergic neurons and the neuronal redox balance…”
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16
A density functional theory study of the free‐radical scavenging activity of aminoguanidine. Comparison with its reactive carbonyl compound and metal scavenging activities
Published in International journal of quantum chemistry (05-07-2019)“…Since protein glycation is related to several human diseases, it is very important to develop molecules that can inhibit its effects. This work adds the…”
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17
Relapse of Human Chorionic Gonadotropin-Induced Hyperthyroidism and Severe Hyperemesis Gravidarum Secondary to Twin-Twin Transfusion Syndrome, With Rapid Recovery Following Fetoscopic Laser Coagulation: Case Report
Published in Frontiers in endocrinology (Lausanne) (16-07-2021)“…Limited data have shown that, compared to uncomplicated twin pregnancies, pregnancies complicated by twin-twin transfusion syndrome (TTTS), a life-threatening…”
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18
Structural basis of homodimerization of the JNK scaffold protein JIP2 and its heterodimerization with JIP1
Published in Structure (London) (05-09-2024)“…The scaffold proteins JIP1 and JIP2 intervene in the c-Jun N-terminal kinase (JNK) pathway to mediate signaling specificity by coordinating the simultaneous…”
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19
Stereotypes and Prejudices in Nursing Prison Activities: A Reflection
Published in Healthcare (Basel) (30-04-2023)“…In the prison environment, the nursing profession has particularly complex peculiarities and aspects, so much so that prison nurses require advanced specialist…”
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Myocardial Repolarization Dispersion and Late Gadolinium Enhancement in Patients With Hypertrophic Cardiomyopathy
Published in Circulation Journal (2014)“…Background: Growing evidence suggests that late gadolinium enhancement (LGE) at cardiac magnetic resonance (CMR) is an additive marker of disease severity, and…”
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