Search Results - "MARINELLI, Michela"

Age matters by McCutcheon, James Edgar, Marinelli, Michela

“…The age of an experimental animal can be a critical variable, yet age matters are often overlooked within neuroscience. Many studies make use of young animals,…”
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Formation of accumbens GluR2-lacking AMPA receptors mediates incubation of cocaine craving by Tseng, Kuei Y, Reimers, Jeremy M, Uejima, Jamie L, Conrad, Kelly L, Marinelli, Michela, Wolf, Marina E, Shaham, Yavin, Heng, Li-Jun

“…Relapse to cocaine use after prolonged abstinence is an important clinical problem. This relapse is often induced by exposure to cues associated with cocaine…”
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Leptin Receptor Signaling in Midbrain Dopamine Neurons Regulates Feeding by Hommel, Jonathan D., Trinko, Richard, Sears, Robert M., Georgescu, Dan, Liu, Zong-Wu, Gao, Xiao-Bing, Thurmon, Jeremy J., Marinelli, Michela, DiLeone, Ralph J.

“…The leptin hormone is critical for normal food intake and metabolism. While leptin receptor ( Lepr) function has been well studied in the hypothalamus, the…”
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Interaction between glucocorticoid hormones, stress and psychostimulant drugs by Marinelli, Michela, Piazza, Pier Vincenzo

“…In this review we summarize data obtained from animal studies showing that glucocorticoid hormones have a facilitatory role on behavioural responses to…”
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Group I mGluR activation reverses cocaine-induced accumulation of calcium-permeable AMPA receptors in nucleus accumbens synapses via a protein kinase C-dependent mechanism by McCutcheon, James E, Loweth, Jessica A, Ford, Kerstin A, Marinelli, Michela, Wolf, Marina E, Tseng, Kuei Y

“…Following prolonged withdrawal from extended access cocaine self-administration in adult rats, high conductance Ca2+ -ermeable AMPA receptors (CP-AMPARs)…”
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Dopamine neurons in the ventral tegmental area fire faster in adolescent rats than in adults by McCutcheon, James E, Conrad, Kelly L, Carr, Steven B, Ford, Kerstin A, McGehee, Daniel S, Marinelli, Michela

“…Adolescence may be a period of vulnerability to drug addiction. In rats, elevated firing activity of ventral tegmental area (VTA) dopamine neurons predicts…”
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The Lateral Preoptic Area and Its Projection to the VTA Regulate VTA Activity and Drive Complex Reward Behaviors by Gordon-Fennell, Adam, Gordon-Fennell, Lydia, Desaivre, Stève, Marinelli, Michela

“…The ventral tegmental area (VTA) underlies motivation and reinforcement of natural rewards. The lateral preoptic area (LPO) is an anterior hypothalamic brain…”
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Fluoxetine potentiates methylphenidate-induced behavioral responses: Enhanced locomotion or stereotypies and facilitated acquisition of cocaine self-administration by Lamoureux, Lorissa, Beverley, Joel A., Marinelli, Michela, Steiner, Heinz

“…The medical psychostimulant methylphenidate (MP) is used to treat attention-deficit hyperactivity disorder and recreationally as a “cognitive enhancer”. MP is…”
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Stress and addiction: glucocorticoid receptor in dopaminoceptive neurons facilitates cocaine seeking by Piazza, Pier Vincenzo, Tronche, François, Ambroggi, Frédéric, Turiault, Marc, Milet, Aude, Deroche-Gamonet, Véronique, Parnaudeau, Sébastien, Balado, Eric, Barik, Jacques, van der Veen, Rixt, Maroteaux, Grégoire, Lemberger, Thomas, Schütz, Günther, Lazar, Monique, Marinelli, Michela

“…The glucocorticoid receptor is a ubiquitous transcription factor mediating adaptation to environmental challenges and stress. Selective Nr3c1 (the…”
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The Lateral Preoptic Area: A Novel Regulator of Reward Seeking and Neuronal Activity in the Ventral Tegmental Area by Gordon-Fennell, Adam G, Will, Ryan G, Ramachandra, Vorani, Gordon-Fennell, Lydia, Dominguez, Juan M, Zahm, Daniel S, Marinelli, Michela

“…The lateral preoptic area (LPO) is a hypothalamic region whose function has been largely unexplored. Its direct and indirect projections to the ventral…”
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Fos After Single and Repeated Self-Administration of Cocaine and Saline in the Rat: Emphasis on the Basal Forebrain and Recalibration of Expression by ZAHM, Daniel S, BECKER, Mary L, FREIMAN, Alexander, STRAUCH, Sara, DEGARMO, Beth, GEISLER, Stefanie, MEREDITH, Gloria E, MARINELLI, Michela

“…The effects of addictive psychostimulant drugs on the brain change over repeated administrations. We evaluated a large sample of brain structures, particularly…”
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Prominent Activation of Brainstem and Pallidal Afferents of the Ventral Tegmental Area by Cocaine by GEISLER, Stefanie, MARINELLI, Michela, DEGARMO, Beth, BECKER, Mary L, FREIMAN, Alexander, BEALES, Mitch, MEREDITH, Gloria E, ZAHM, Daniel S

“…Blockade of monoamine transporters by cocaine should not necessarily lead to certain observed consequences of cocaine administration, including increased…”
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Persistent Increases in Cocaine-Seeking Behavior After Acute Exposure to Cold Swim Stress by Conrad, Kelly L, McCutcheon, James E, Cotterly, Lindsay M, Ford, Kerstin A, Beales, Mitch, Marinelli, Michela

“…Background Acute and chronic stress reinstates drug-seeking behavior. Current animal models show that these effects are contingent (temporally, contextually,…”
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Impulse activity of midbrain dopamine neurons modulates drug-seeking behavior by Marinelli, Michela, Cooper, Donald C, Baker, Lorinda K, White, Francis J

“…Withdrawal from non-contingent exposure to psychostimulants increases the activity of midbrain dopamine cells and impairs the function of impulse-regulating…”
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The dopaminergic hyper-responsiveness of the shell of the nucleus accumbens is hormone-dependent by Barrot, Michel, Marinelli, Michela, Abrous, Djoher Nora, Rougé-Pont, Françoise, Le Moal, Michel, Piazza, Pier Vincenzo

“…The dopaminergic projection to the shell of the nucleus accumbens is the most reactive to stress, reward and drugs of abuse and this subregion of the nucleus…”
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The neurosteroid allopregnanolone increases dopamine release and dopaminergic response to morphine in the rat nucleus accumbens by Rougé-Pont, Françoise, Mayo, Willy, Marinelli, Michela, Gingras, Mireille, Le Moal, Michel, Piazza, Pier Vincenzo

“…Neurosteroids are a subclass of steroids that can be synthesized in the central nervous system independently from peripheral sources. Clinical studies in…”
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Glucocorticoids and behavioral effects of psychostimulants. II: cocaine intravenous self-administration and reinstatement depend on glucocorticoid levels by Deroche, V, Marinelli, M, Le Moal, M, Piazza, P V

“…Observations suggest that corticosterone, the principal glucocorticoid hormone in the rat, can modulate the behavioral effects of drugs of abuse. In this…”
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Dopamine-Dependent Responses to Morphine Depend on Glucocorticoid Receptors by Marinelli, Michela, Aouizerate, Bruno, Barrot, Michel, Le Moal, Michel, Piazza, Pier Vincenzo

“…Previous work has shown that glucocorticoid hormones facilitate the behavioral and dopaminergic effects of morphine. In this study we examined the possible…”
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Methylphenidate with or without fluoxetine triggers reinstatement of cocaine seeking behavior in rats by Lamoureux, Lorissa, Beverley, Joel, Steiner, Heinz, Marinelli, Michela

“…Methylphenidate (MP) is commonly prescribed to treat attention-deficit hyperactivity disorder (ADHD). MP is also taken for non-medical purposes as a…”
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Adolescent-onset of cocaine use is associated with heightened stress-induced reinstatement of cocaine seeking by Wong, Wai Chong, Marinelli, Michela

“…Adolescent rats take cocaine more readily than adults, are more sensitive to lower doses of the drug and work harder for it. It remains unknown if…”
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