Search Results - "MARIETTE, XAVIER"

B cells in the pathogenesis of primary Sjögren syndrome by Nocturne, Gaëtane, Mariette, Xavier

“…Key Points Genetic risk factors associated with primary Sjögren syndrome (pSS) can promote B cell activation, as can epigenetic changes, which can sometimes…”
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Systemic and organ-specific immune-related manifestations of COVID-19 by Ramos-Casals, Manuel, Brito-Zerón, Pilar, Mariette, Xavier

“…Immune-related manifestations are increasingly recognized conditions in patients with COVID-19, with around 3,000 cases reported worldwide comprising more than…”
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Sjögren Syndrome‐associated lymphomas: an update on pathogenesis and management by Nocturne, Gaetane, Mariette, Xavier

“…Summary Primary Sjögren Syndrome (pSS) is an autoimmune disease associated with an increased risk of lymphoma. Lymphomas complicating pSS are mostly low‐grade…”
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Current and future therapies for primary Sjögren syndrome by Seror, Raphaèle, Nocturne, Gaetane, Mariette, Xavier

“…Primary Sjögren syndrome (pSS) is a systemic autoimmune disease that is characterized by a triad of symptoms that affect all patients (dryness, pain and…”
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Lymphomas complicating primary Sjögren's syndrome: from autoimmunity to lymphoma by Nocturne, Gaetane, Pontarini, Elena, Bombardieri, Michele, Mariette, Xavier

“…Lymphoma development is the most serious complication of SS and the main factor impacting on mortality rate in patients with this condition. Lymphomas in SS…”
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Chronic inflammatory arthritis following checkpoint inhibitor therapy for cancer: game changing implications by Calabrese, Leonard, Mariette, Xavier

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Immune-related adverse events of checkpoint inhibitors by Ramos-Casals, Manuel, Brahmer, Julie R., Callahan, Margaret K., Flores-Chávez, Alejandra, Keegan, Niamh, Khamashta, Munther A., Lambotte, Olivier, Mariette, Xavier, Prat, Aleix, Suárez-Almazor, Maria E.

“…Cancer immunotherapies have changed the landscape of cancer treatment during the past few decades. Among them, immune checkpoint inhibitors, which target PD-1,…”
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Lack of placental transfer of certolizumab pegol during pregnancy: results from CRIB, a prospective, postmarketing, pharmacokinetic study by Mariette, Xavier, Förger, Frauke, Abraham, Bincy, Flynn, Ann D, Moltó, Anna, Flipo, René-Marc, van Tubergen, Astrid, Shaughnessy, Laura, Simpson, Jeff, Teil, Marie, Helmer, Eric, Wang, Maggie, Chakravarty, Eliza F

“…There is a need for effective and safe treatment during pregnancy in women with chronic inflammatory diseases. This study evaluated placental transfer of…”
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Long-term safety of tofacitinib for the treatment of rheumatoid arthritis up to 8.5 years: integrated analysis of data from the global clinical trials by Cohen, Stanley B, Tanaka, Yoshiya, Mariette, Xavier, Curtis, Jeffrey R, Lee, Eun Bong, Nash, Peter, Winthrop, Kevin L, Charles-Schoeman, Christina, Thirunavukkarasu, Krishan, DeMasi, Ryan, Geier, Jamie, Kwok, Kenneth, Wang, Lisy, Riese, Richard, Wollenhaupt, Jürgen

“…Tofacitinib is an oral Janus kinase inhibitor for the treatment of rheumatoid arthritis (RA). We report an integrated safety summary of tofacitinib from two…”
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Rheumatoid arthritis and polymyalgia rheumatica occurring after immune checkpoint inhibitor treatment by Belkhir, Rakiba, Burel, Sébastien Le, Dunogeant, Laetitia, Marabelle, Aurélien, Hollebecque, Antoine, Besse, Benjamin, Leary, Alexandra, Voisin, Anne-Laure, Pontoizeau, Clémence, Coutte, Laetitia, Pertuiset, Edouard, Mouterde, Gaël, Fain, Olivier, Lambotte, Olivier, Mariette, Xavier

“…Immune checkpoint inhibitors (ICIs) targeting cytotoxic T-lymphocyte-associated protein 4 and programmed cell death protein 1 (PD-1) have demonstrated improved…”
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Monocyte/Macrophage Abnormalities Specific to Rheumatoid Arthritis Are Linked to miR-155 and Are Differentially Modulated by Different TNF Inhibitors by Paoletti, Audrey, Rohmer, Julien, Ly, Bineta, Pascaud, Juliette, Rivière, Elodie, Seror, Raphaele, Le Goff, Benoit, Nocturne, Gaetane, Mariette, Xavier

“…Proinflammatory macrophages and miR-155 are increased in patients with rheumatoid arthritis (RA). We studied membrane TNF (mTNF) expression on blood monocytes,…”
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EULAR Sjogren's syndrome disease activity index: development of a consensus systemic disease activity index for primary Sjogren's syndrome by Seror, Raphaèle, Ravaud, Philippe, Bowman, Simon J, Baron, Gabriel, Tzioufas, Athanasios, Theander, Elke, Gottenberg, Jacques-Eric, Bootsma, Hendrika, Mariette, Xavier, Vitali, Claudio

“…To develop a disease activity index for patients with primary Sjögren's syndrome (SS): the European League Against Rheumatism (EULAR) Sjögren's syndrome…”
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Clonal CD8 + T-cell expansion is associated with complete response to elranatamab in refractory multiple myeloma by Krzysiek, Roman, Bitoun, Samuel, Belkhir, Rakiba, Hacein-Bey-Abina, Salima, Mariette, Xavier

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Interferon signature in systemic autoimmune diseases: what does it mean? by Nocturne, Gaetane, Mariette, Xavier

“…The first description of the involvement of interferons (IFN) in systemic autoimmune diseases (AID) dates back more than 40 years.1 IFNs play a crucial role in…”
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Characterization of systemic disease in primary Sjögren's syndrome: EULAR-SS Task Force recommendations for articular, cutaneous, pulmonary and renal involvements by Ramos-Casals, Manuel, Brito-Zerón, Pilar, Seror, Raphaèle, Bootsma, Hendrika, Bowman, Simon J, Dörner, Thomas, Gottenberg, Jacques-Eric, Mariette, Xavier, Theander, Elke, Bombardieri, Stefano, De Vita, Salvatore, Mandl, Thomas, Ng, Wan-Fai, Kruize, Aike, Tzioufas, Athanasios, Vitali, Claudio

“…To reach a European consensus on the definition and characterization of the main organ-specific extraglandular manifestations in primary SS. The EULAR-SS Task…”
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Defining conditions where long-term glucocorticoid treatment has an acceptably low level of harm to facilitate implementation of existing recommendations: viewpoints from an EULAR task force by Strehl, Cindy, Bijlsma, Johannes W J, de Wit, Maarten, Boers, Maarten, Caeyers, Nele, Cutolo, Maurizio, Dasgupta, Bhaskar, Dixon, William G, Geenen, Rinie, Huizinga, Tom W J, Kent, Alison, de Thurah, Annette Ladefoged, Listing, Joachim, Mariette, Xavier, Ray, David W, Scherer, Hans U, Seror, Raphaèle, Spies, Cornelia M, Tarp, Simon, Wiek, Dieter, Winthrop, Kevin L, Buttgereit, Frank

“…There is convincing evidence for the known and unambiguously accepted beneficial effects of glucocorticoids at low dosages. However, the implementation of…”
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Cytometry by time-of-flight immunophenotyping identifies a blood Sjögren's signature correlating with disease activity and glandular inflammation by Mingueneau, Michael, PhD, Boudaoud, Saida, MSc, Haskett, Scott, MSc, Reynolds, Taylor L., DVM, PhD, Nocturne, Gaetane, MD, PhD, Norton, Elizabeth, BSc, Zhang, Xueli, BSc, Constant, Myrtha, BSc, Park, Daniel, MSc, Wang, Wenting, PhD, Lazure, Thierry, MD, Le Pajolec, Christine, MD, Ergun, Ayla, PhD, Mariette, Xavier, MD, PhD

“…Background Mass cytometry has recently emerged as a promising tool for clinical research. However, few studies have demonstrated its benefit for patient…”
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Immune interventions in COVID-19: a matter of time? by Plaçais, Léo, Richier, Quentin, Noël, Nicolas, Lacombe, Karine, Mariette, Xavier, Hermine, Olivier

“…As the COVID-19 pandemic is still ongoing, and considering the lack of efficacy of antiviral strategies to this date, and the reactive hyperinflammation…”
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Validation of EULAR primary Sjögren's syndrome disease activity (ESSDAI) and patient indexes (ESSPRI) by Seror, Raphaèle, Theander, Elke, Brun, Johan G, Ramos-Casals, Manel, Valim, Valeria, Dörner, Thomas, Bootsma, Hendrika, Tzioufas, Athanasios, Solans-Laqué, Roser, Mandl, Thomas, Gottenberg, Jacques-Eric, Hachulla, Eric, Sivils, Kathy L, Ng, Wan-Fai, Fauchais, Anne-Laure, Bombardieri, Stefano, Valesini, Guido, Bartoloni, Elena, Saraux, Alain, Tomsic, Matija, Sumida, Takayuki, Nishiyama, Susumu, Caporali, Roberto, Kruize, Aike A, Vollenweider, Cristina, Ravaud, Philippe, Vitali, Claudio, Mariette, Xavier, Bowman, Simon J

“…To validate the two recently developed disease activity indexes for assessment of primary Sjögren's syndrome (SS): the European League Against Rheumatism…”
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Role of good oral hygiene on clinical evolution of rheumatoid arthritis: a randomized study nested in the ESPOIR cohort by Mariette, Xavier, Perrodeau, Elodie, Verner, Christian, Struillou, Xavier, Picard, Nicolas, Schaeverbeke, Thierry, Constantin, Arnaud, Ravaud, Philippe, Bouchard, Philippe

“…Abstract Objective There is a relationship between RA and periodontal disease. We aimed to investigate if a good oral hygiene could improve activity of RA…”
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