Search Results - "MARGOLESE, R"

Effect of preoperative chemotherapy on the outcome of women with operable breast cancer by Fisher, B, Bryant, J, Wolmark, N, Mamounas, E, Brown, A, Fisher, E R, Wickerham, D L, Begovic, M, DeCillis, A, Robidoux, A, Margolese, R G, Cruz, Jr, A B, Hoehn, J L, Lees, A W, Dimitrov, N V, Bear, H D

“…To determine, in women with primary operable breast cancer, if preoperative doxorubicin (Adriamycin) and cyclophosphamide (Cytoxan; AC) therapy yields a better…”
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Effect of preoperative chemotherapy on the outcome of women with operable breast cancer by Fisher, B, Bryant, J, Wolmark, N, Mamounas, E, Brown, A, Fisher, E R, Wickerham, D L, Begovic, M, DeCillis, A, Robidoux, A, Margolese, R G, Cruz, Jr, A B, Hoehn, J L, Lees, A W, Dimitrov, N V, Bear, H D

“…To determine, in women with primary operable breast cancer, if preoperative doxorubicin (Adriamycin) and cyclophosphamide (Cytoxan; AC) therapy yields a better…”
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Effect of preoperative chemotherapy on local-regional disease in women with operable breast cancer: findings from National Surgical Adjuvant Breast and Bowel Project B-18 by Fisher, B, Brown, A, Mamounas, E, Wieand, S, Robidoux, A, Margolese, R G, Cruz, Jr, A B, Fisher, E R, Wickerham, D L, Wolmark, N, DeCillis, A, Hoehn, J L, Lees, A W, Dimitrov, N V

“…To determine whether preoperative doxorubicin and cyclophosphamide (AC) permits more lumpectomies to be performed and decreases the incidence of positive nodes…”
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Tamoxifen and Chemotherapy for Lymph Node-Negative, Estrogen Receptor-Positive Breast Cancer by Fisher, Bernard, Dignam, James, Emir, Birol, Bryant, John, DeCillis, Arthur, Wolmark, Norman, Wickerham, D. Lawrence, Dimitrov, Nikolay V., Abramson, Neil, Atkins, James N., Shibata, Henry, Deschenes, Luc, Margolese, Richard G.

“…Background: The B-20 study of the National Surgical Adjuvant Breast and Bowel Project (NSABP) was conducted to determine whether chemotherapy plus tamoxifen…”
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Long-Term Outcomes of Invasive Ipsilateral Breast Tumor Recurrences After Lumpectomy in NSABP B-17 and B-24 Randomized Clinical Trials for DCIS by WAPNIR, Irene L, DIGNAM, James J, WOLMARK, Norman, FISHER, Bernard, MAMOUNAS, Eleftherios P, ANDERSON, Stewart J, JULIAN, Thomas B, LAND, Stephanie R, MARGOLESE, Richard G, SWAIN, Sandra M, COSTANTINO, Joseph P

“…Ipsilateral breast tumor recurrence (IBTR) is the most common failure event after lumpectomy for ductal carcinoma in situ (DCIS). We evaluated invasive IBTR…”
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Tamoxifen in treatment of intraductal breast cancer: National Surgical Adjuvant Breast and Bowel Project B-24 randomised controlled trial by Fisher, Bernard, Dignam, James, Wolmark, Norman, Wickerham, D Lawrence, Fisher, Edwin R, Mamounas, Eleftherios, Smith, Roy, Begovic, Mirsada, Dimitrov, Nikolay V, Margolese, Richard G, Kardinal, Carl G, Kavanah, Maureen T, Fehrenbacher, Louis, Oishi, Robert H

“…We have shown previously that lumpectomy with radiation therapy was more effective than lumpectomy alone for the treatment of ductal carcinoma in situ (DCIS)…”
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Five Versus More Than Five Years of Tamoxifen Therapy for Breast Cancer Patients With Negative Lymph Nodes and Estrogen Receptor-Positive Tumors by Fisher, Bernard, Dignam, James, Bryant, John, DeCillis, Arthur, Wickerham, D. Lawrence, Wolmark, Norman, Costantino, Joseph, Redmond, Carol, Fisher, Edwin R., Bowman, David M., Deschênes, Luc, Dimitrov, Nikolay V., Margolese, Richard G., Robidoux, André, Shibata, Henry, Terz, Jose, Paterson, A. H. G., Feldman, Merrill I., Farrar, William, Evans, James, Lickley, H. Lavina

“…Background: In 1982, the National Surgical Adjuvant Breast and Bowel Project initiated a randomized, double-blinded, placebo-controlled trial (B-14) to…”
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Lumpectomy and radiation therapy for the treatment of intraductal breast cancer: findings from National Surgical Adjuvant Breast and Bowel Project B-17 by Fisher, B, Dignam, J, Wolmark, N, Mamounas, E, Costantino, J, Poller, W, Fisher, E R, Wickerham, D L, Deutsch, M, Margolese, R, Dimitrov, N, Kavanah, M

“…In 1993, findings from a National Surgical Adjuvant Breast and Bowel Project (NSABP) trial to evaluate the worth of radiation therapy after lumpectomy…”
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Tamoxifen and Chemotherapy for Axillary Node-Negative, Estrogen Receptor–Negative Breast Cancer: Findings From National Surgical Adjuvant Breast and Bowel Project B-23 by FISHER, Bernard, ANDERSON, Stewart, ROMOND, Edward H, KARDINAL, Carl G, SHIBATA, Henry R, MARGOLESE, Richard G, FARRAR, William B, TAN-CHIU, Elizabeth, WOLMARK, Norman, WICKERHAM, D. Lawrence, FISHER, Edwin R, DIMITROV, Nikolay V, ATKINS, James N, ABRAMSON, Neil, MERAJVER, Sofia

“…Uncertainty about the relative worth of doxorubicin/cyclophosphamide (AC) and cyclophosphamide/methotrexate/fluorouracil (CMF), as well as doubt about the…”
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Sequential methotrexate and fluorouracil for the treatment of node-negative breast cancer patients with estrogen receptor-negative tumors: eight-year results from National Surgical Adjuvant Breast and Bowel Project (NSABP) B-13 and first report of findings from NSABP B-19 comparing methotrexate and fluorouracil with conventional cyclophosphamide, methotrexate, and fluorouracil by Fisher, B, Dignam, J, Mamounas, E P, Costantino, J P, Wickerham, D L, Redmond, C, Wolmark, N, Dimitrov, N V, Bowman, D M, Glass, A G, Atkins, J N, Abramson, N, Sutherland, C M, Aron, B S, Margolese, R G

“…To compare sequential methotrexate (M) and fluorouracil (F) (M-->F) with surgery (National Surgical Adjuvant Breast and Bowel Project [NSABP] B-13) and…”
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Significance of ipsilateral breast tumour recurrence after lumpectomy by Fisher, B, Anderson, S, Fisher, E R, Redmond, C, Wickerham, D L, Wolmark, N, Mamounas, E P, Deutsch, M, Margolese, R

“…Breast cancer treatment trials from the US National Surgical Adjuvant Breast and Bowel Project have established breast-conserving operations as a replacement…”
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Long-term tamoxifen citrate use and potential ocular toxicity by Gorin, Michael B., Day, Richard, Costantino, Joseph P., Fisher, Bernard, Redmond, Carol K., Wickerham, Lawrence, Gomolin, Julius E.S., Margolese, Richard G., Mathen, Mathen K., Bowman, David M., Kaufmann, David, Dimitrov, Nikolay V., Singerman, Lawrence J., Bornstein, Richard, Wolmark, Norman

“…To estimate the prevalence of abnormalities in visual function and ocular structures associated with the long-term use of tamoxifen citrate. A single-masked,…”
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Postoperative chemotherapy and tamoxifen compared with tamoxifen alone in the treatment of positive-node breast cancer patients aged 50 years and older with tumors responsive to tamoxifen: results from the National Surgical Adjuvant Breast and Bowel Project B-16 by Fisher, B, Redmond, C, Legault-Poisson, S, Dimitrov, N V, Brown, A M, Wickerham, D L, Wolmark, N, Margolese, R G, Bowman, D, Glass, A G

“…The National Surgical Adjuvant Breast and Bowel Project (NSABP) conducted a randomized clinical trial to determine whether tamoxifen (TAM) plus chemotherapy is…”
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Effect of tamoxifen on serum insulinlike growth factor I levels in stage I breast cancer patients by Pollak, M, Costantino, J, Polychronakos, C, Blauer, S A, Guyda, H, Redmond, C, Fisher, B, Margolese, R

“…Insulinlike growth factor I (IGF-I) has been shown to be a potent mitogen for breast cancer cells in vitro, and IGF-I receptors have been demonstrated on human…”
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Screening mammography in young women: a different perspective by Margolese, R

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Surgical considerations for invasive breast cancer by Margolese, R G

“…The 1992 NIH Consensus Development Conference reported that "breast conservation treatment is an appropriate method of primary therapy for the majority of…”
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Five-year results of a randomized clinical trial comparing total mastectomy and segmental mastectomy with or without radiation in the treatment of breast cancer by Fisher, B, Bauer, M, Margolese, R, Poisson, R, Pilch, Y, Redmond, C, Fisher, E, Wolmark, N, Deutsch, M, Montague, E

“…In 1976 we began a randomized trial to evaluate breast conservation by a segmental mastectomy in the treatment of Stage I and II breast tumors less than or…”
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Surgical considerations in preoperative chemotherapy of breast cancer by Margolese, R G

“…Primary systemic chemotherapy for breast cancer was initially directed at downsizing tumors to make them acceptable candidates for breast-conserving surgery…”
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How do we interpret the results of the Breast Cancer Prevention trial? by Margolese, R G

“…The results of clinical trials are applicable only to populations that resemble the trial participants. Although we should not begin to broaden the use of…”
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Ten-year results of a randomized clinical trial comparing radical mastectomy and total mastectomy with or without radiation by Fisher, B, Redmond, C, Fisher, E R, Bauer, M, Wolmark, N, Wickerham, D L, Deutsch, M, Montague, E, Margolese, R, Foster, R

“…In 1971 we began a randomized trial to compare alternative local and regional treatments of breast cancer, all of which employ breast removal. Life-table…”
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