Search Results - "MAREE, Francois F"

Viral dynamics and immune responses to foot-and-mouth disease virus in African buffalo (Syncerus caffer) by Perez-Martin, Eva, Beechler, Brianna, Zhang, Fuquan, Scott, Katherine, de Klerk-Lorist, Lin-Mari, Limon, Georgina, Dugovich, Brian, Gubbins, Simon, Botha, Arista, Hetem, Robyn, van Schalkwyk, Louis, Juleff, Nicholas, Maree, Francois F., Jolles, Anna, Charleston, Bryan

“…Foot-and-mouth disease (FMD) is one of the most important livestock diseases restricting international trade. While African buffalo ( Syncerus caffer ) act as…”
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Symmetrical arrangement of positively charged residues around the 5-fold axes of SAT type foot-and-mouth disease virus enhances cell culture of field viruses by Chitray, Melanie, Kotecha, Abhay, Nsamba, Peninah, Ren, Jingshan, Maree, Sonja, Ramulongo, Tovhowani, Paul, Guntram, Theron, Jacques, Fry, Elizabeth E, Stuart, David I, Maree, Francois F

“…Field isolates of foot-and-mouth disease viruses (FMDVs) utilize integrin-mediated cell entry but many, including Southern African Territories (SAT) viruses,…”
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Tracking the Antigenic Evolution of Foot-and-Mouth Disease Virus by Reeve, Richard, Borley, Daryl W, Maree, Francois F, Upadhyaya, Sasmita, Lukhwareni, Azwidowi, Esterhuysen, Jan J, Harvey, William T, Blignaut, Belinda, Fry, Elizabeth E, Parida, Satya, Paton, David J, Mahapatra, Mana

“…Quantifying and predicting the antigenic characteristics of a virus is something of a holy grail for infectious disease research because of its central…”
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Efficacy of SAT2 Foot-and-Mouth Disease Vaccines Formulated with Montanide ISA 206B and Quil-A Saponin Adjuvants by Rathogwa, Ntungufhadzeni M., Scott, Katherine A., Opperman, Pamela, Theron, Jacques, Maree, Francois F.

“…The effective control of foot-and-mouth disease (FMD) relies strongly on the separation of susceptible and infected livestock or susceptible livestock and…”
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Analysis of SAT Type Foot-And-Mouth Disease Virus Capsid Proteins and the Identification of Putative Amino Acid Residues Affecting Virus Stability by Maree, Francois F, Blignaut, Belinda, de Beer, Tjaart A. P, Rieder, Elizabeth, Qiu, Jianming

“…Foot-and-mouth disease virus (FMDV) initiates infection by adhering to integrin receptors on target cells, followed by cell entry and disassembly of the virion…”
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Sequence-Based Prediction for Vaccine Strain Selection and Identification of Antigenic Variability in Foot-and-Mouth Disease Virus by Reeve, Richard, Blignaut, Belinda, Esterhuysen, Jan J, Opperman, Pamela, Matthews, Louise, Fry, Elizabeth E, De Beer, Tjaart A.P, Theron, Jacques, Rieder, Elizabeth, Vosloo, Wilna, O'Neill, Hester G, Haydon, Daniel T, Maree, Francois F

“…Identifying when past exposure to an infectious disease will protect against newly emerging strains is central to understanding the spread and the severity of…”
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Genetic Basis of Antigenic Variation of SAT3 Foot-And-Mouth Disease Viruses in Southern Africa by Maake, Lorens, Harvey, William T, Rotherham, Lia, Opperman, Pamela, Theron, Jacques, Reeve, Richard, Maree, Francois F

“…Foot-and-mouth disease (FMD) continues to be a major burden for livestock owners in endemic countries and a continuous threat to FMD-free countries. The…”
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Crystal structure of the 3C protease from Southern African Territories type 2 foot-and-mouth disease virus by Yang, Jingjie, Leen, Eoin N, Maree, Francois F, Curry, Stephen

“…The replication of foot-and-mouth disease virus (FMDV) is dependent on the virus-encoded 3C protease (3C(pro)). As in other picornaviruses, 3C(pro) performs…”
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The Culicoides sonorensis inhibitor of apoptosis 1 protein protects mammalian cells from apoptosis induced by infection with African horse sickness virus and bluetongue virus by Vermaak, Elaine, Maree, Francois F., Theron, Jacques

“…•Culicoides sonorensis cells encode an inhibitor of apoptosis protein, named CsIAP1.•CsIAP1 is essential for C. sonorensis cell viability.•CsIAP1 suppresses…”
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Structure-based energetics of protein interfaces guides foot-and-mouth disease virus vaccine design by Kotecha, Abhay, Seago, Julian, Scott, Katherine, Burman, Alison, Loureiro, Silvia, Ren, Jingshan, Porta, Claudine, Ginn, Helen M, Jackson, Terry, Perez-Martin, Eva, Siebert, C Alistair, Paul, Guntram, Huiskonen, Juha T, Jones, Ian M, Esnouf, Robert M, Fry, Elizabeth E, Maree, Francois F, Charleston, Bryan, Stuart, David I

“…Foot-and-mouth disease virus (FMDV) capsids are often unstable, thus limiting their use as vaccines. A computational method was used to strengthen…”
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SAT2 Foot-and-Mouth Disease Virus Structurally Modified for Increased Thermostability by Scott, Katherine A, Kotecha, Abhay, Seago, Julian, Ren, Jingshan, Fry, Elizabeth E, Stuart, David I, Charleston, Bryan, Maree, Francois F

“…Foot-and-mouth disease virus (FMDV), particularly strains of the O and SAT serotypes, is notoriously unstable. Consequently, vaccines derived from heat-labile…”
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Inherent biophysical stability of foot-and-mouth disease SAT1, SAT2 and SAT3 viruses by Scott, Katherine A., Maake, Lorens, Botha, Elizabeth, Theron, Jacques, Maree, Francois F.

“…[Display omitted] •Phylogenetic analyses classified field FMD viruses into respective topotypes.•SAT2 and SAT3 viruses similar thermostability, SAT1 viruses…”
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Pathogenesis, biophysical stability and phenotypic variance of SAT2 foot-and-mouth disease virus by Ramulongo, Tovhowani D., Maree, Francois F., Scott, Katherine, Opperman, Pamela, Mutowembwa, Paidamwoyo, Theron, Jacques

“…•FMD clinical signs range from mild to severe or subclinical.•Pathogenesis of SAT2 viruses did not correlate with cell killing or viral fitness.•SAT2 viruses…”
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Intra-serotype SAT2 chimeric foot-and-mouth disease vaccine protects cattle against FMDV challenge by Maree, Francois F, Nsamba, Peninah, Mutowembwa, Paidamwoyo, Rotherham, Lia S, Esterhuysen, Jan, Scott, Katherine

“…Highlights • Cattle were immunized with an intra-serotype chimeric foot-and-mouth disease virus vaccine. • The chimeric vaccine elicited a strong neutralizing…”
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Persistent Infection of African Buffalo (Syncerus caffer) with Foot-and-Mouth Disease Virus: Limited Viral Evolution and No Evidence of Antibody Neutralization Escape by Cortey, Martí, Ferretti, Luca, Pérez-Martín, Eva, Zhang, Fuquan, de Klerk-Lorist, Lin-Mari, Scott, Katherine, Freimanis, Graham, Seago, Julian, Ribeca, Paolo, van Schalkwyk, Louis, Juleff, Nicholas D, Maree, Francois F, Charleston, Bryan

“…African buffaloes ( ) are the principal "carrier" hosts of foot-and-mouth disease virus (FMDV). Currently, the epithelia and lymphoid germinal centers of the…”
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Evaluation of immune responses of stabilised SAT2 antigens of foot-and-mouth disease in cattle by Scott, Katherine A, Rathogwa, N.M, Capozzo, A.V, Maree, Francois F

“…Abstract Foot-and-mouth disease (FMD) vaccines with improved stability and less reliant on a cold-chain are needed to improve the longevity of immune responses…”
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Serological and phylogenetic characterization of foot and mouth disease viruses from Uganda during cross‐sectional surveillance study in cattle between 2014 and 2017 by Mwiine, Frank Norbert, Velazquez‐Salinas, Lauro, Ahmed, Zaheer, Ochwo, Sylvester, Munsey, Anna, Kenney, Mary, Lutwama, Julius J., Maree, Francois F., Lobel, Leslie, Perez, Andres M., Rodriguez, Luis L., VanderWaal, Kimberly, Rieder, Elizabeth

“…Here, we report the results of a cross‐sectional study designed to monitor the circulation and genetic diversity of foot and mouth disease virus (FMDV) in…”
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African horse sickness virus infects BSR cells through macropinocytosis by Vermaak, Elaine, Conradie, Andelé M, Maree, Francois F, Theron, Jacques

“…Abstract Cellular pathways involved in cell entry by African horse sickness virus (AHSV), a member of the Orbivirus genus within the Reoviridae family, have…”
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The history of foot-and-mouth disease virus serotype C: the first known extinct serotype? by Paton, David J, Di Nardo, Antonello, Knowles, Nick J, Wadsworth, Jemma, Pituco, Edviges M, Cosivi, Ottorino, Rivera, Alejandro M, Kassimi, Labib Bakkali, Brocchi, Emiliana, de Clercq, Kris, Carrillo, Consuelo, Maree, Francois F, Singh, Raj K, Vosloo, Wilna, Park, Min-Kyung, Sumption, Keith J, Ludi, Anna B, King, Donald P

“…Abstract Foot-and-mouth disease (FMD) is a highly contagious animal disease caused by an RNA virus subdivided into seven serotypes that are unevenly…”
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Synthesis of empty african horse sickness virus particles by Maree, Sonja, Maree, Francois F., Putterill, John F., de Beer, Tjaart A.P., Huismans, Henk, Theron, Jacques

“…•Synthesized fully assembled, bilayered AHSV CLPs in vivo.•Synthesized partial and complete triple layered AHSV VLPs.•Rationally engineered and co-synthesized…”
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