Search Results - "MARDASSI, Helmi"

Delineating the evolutionary pathway to multidrug-resistant outbreaks of a Mycobacterium tuberculosis L4.1.2.1/Haarlem sublineage by Dekhil, Naira, Mardassi, Helmi

“…•Propensity for rapid transmission of the L4.1.2.1 sublineage in northern Tunisia.•The L4.1.2.1 sublineage is the primary cause of multidrug-resistant…”
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Genomic changes underpinning the emergence of a successful Mycobacterium tuberculosis Latin American and Mediterranean clonal complex by Dekhil, Naira, Mardassi, Helmi

“…The Latin American and Mediterranean sublineage (L4.3/LAM) is the most common generalist sublineage of lineage 4 (L4), yet certain L4.3/LAM genotypes appear to…”
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On the onset and dispersal of a major MDR TB clone among HIV-negative patients, Tunisia by Dekhil, Naira, Mardassi, Helmi

“…To carry out a whole genome sequencing (WGS)-based investigation on the emergence and spread of the largest multidrug-resistant tuberculosis (MDR TB) outbreak…”
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Phenotypic and genomic hallmarks of a novel, potentially pathogenic rapidly growing Mycobacterium species related to the Mycobacterium fortuitum complex by Gharbi, Reem, Khanna, Varun, Frigui, Wafa, Mhenni, Besma, Brosch, Roland, Mardassi, Helmi

“…Previously, we have identified a putative novel rapidly growing Mycobacterium species, referred to as TNTM28, recovered from the sputum of an apparently…”
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Nontuberculous mycobacteria isolated from specimens of pulmonary tuberculosis suspects, Northern Tunisia: 2002–2016 by Gharbi, Reem, Mhenni, Besma, Ben Fraj, Saloua, Mardassi, Helmi

“…Reports on the worldwide ascending trend of pulmonary nontuberculous mycobacteria (NTM) isolation rates and their effective role in respiratory tract…”
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Successful expansion of Mycobacterium tuberculosis Latin American and Mediterranean sublineage (L4.3/LAM) in Tunisia mainly driven by a single, long-established clonal complex by Skhairia, Mohamed Amine, Dekhil, Naira, Mhenni, Besma, Fradj, Saloua Ben, Mardassi, Helmi

“…•The Mycobacterium tuberculosis L4.3/Latin American and Mediterranean (LAM) sublineage is the most prevalent in Tunisia.•The success of L4.3/LAM is mainly…”
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A gain-of-function mutation in zinc cluster transcription factor Rob1 drives Candida albicans adaptive growth in the cystic fibrosis lung environment by Gnaien, Mayssa, Maufrais, Corinne, Rebai, Yasmine, Kallel, Aicha, Ma, Laurence, Hamouda, Samia, Khalsi, Fatma, Meftah, Khaoula, Smaoui, Hanen, Khemiri, Monia, Hadj Fredj, Sondes, Bachellier-Bassi, Sophie, Najjar, Imène, Messaoud, Taieb, Boussetta, Khadija, Kallel, Kalthoum, Mardassi, Helmi, d'Enfert, Christophe, Bougnoux, Marie-Elisabeth, Znaidi, Sadri

“…Candida albicans chronically colonizes the respiratory tract of patients with Cystic Fibrosis (CF). It competes with CF-associated pathogens (e.g. Pseudomonas…”
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Evolutionary Trends of the Transposase-Encoding Open Reading Frames A and B (orfA and orfB) of the Mycobacterial IS6110 Insertion Sequence by Thabet, Sara, Namouchi, Amine, Mardassi, Helmi

“…The IS6110 insertion sequence, a member of the IS3 family of insertion sequences, was found to be specific to the Mycobacterium tuberculosis complex (MTBC)…”
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Automated IS6110-based fingerprinting of Mycobacterium tuberculosis: Reaching unprecedented discriminatory power and versatility by Dekhil, Naira, Skhairia, Mohamed Amine, Mhenni, Besma, Ben Fradj, Saloua, Warren, Rob, Mardassi, Helmi

“…Several technical hurdles and limitations have restricted the use of IS6110 restriction fragment length polymorphism (IS6110 RFLP), the most effective typing…”
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MDR-TB Outbreak among HIV-Negative Tunisian Patients followed during 11 Years by Dekhil, Naira, Meftahi, Nedra, Mhenni, Besma, Ben Fraj, Saloua, Haltiti, Raja, Belhaj, Sameh, Mardassi, Helmi

“…Multidrug-resistant tuberculosis (MDR-TB) outbreaks that evolve, from the outset, in a context strictly negative for HIV infection deserve special…”
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Spread of multidrug resistance among Ureaplasma serovars, Tunisia by Boujemaa, Safa, Mlik, Béhija, Ben Allaya, Amina, Mardassi, Helmi, Ben Abdelmoumen Mardassi, Boutheina

“…spp. have been implicated in a variety of clinical conditions and certain serovars are likely to be disease-associated. Hence, the ascending trend of spp…”
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Evolution of smooth tubercle Bacilli PE and PE_PGRS genes: evidence for a prominent role of recombination and imprint of positive selection by Namouchi, Amine, Karboul, Anis, Fabre, Michel, Gutierrez, Maria Cristina, Mardassi, Helmi

“…PE and PE_PGRS are two mycobateria-restricted multigene families encoding membrane associated and secreted proteins that have expanded mainly in the pathogenic…”
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Escherichia coli Nissle 1917 Antagonizes Candida albicans Growth and Protects Intestinal Cells from C. albicans-Mediated Damage by Rebai, Yasmine, Wagner, Lysett, Gnaien, Mayssa, Hammer, Merle L., Kapitan, Mario, Niemiec, Maria Joanna, Mami, Wael, Mosbah, Amor, Messadi, Erij, Mardassi, Helmi, Vylkova, Slavena, Jacobsen, Ilse D., Znaidi, Sadri

“…Candida albicans is a pathobiont of the gastrointestinal tract. It can contribute to the diversity of the gut microbiome without causing harmful effects. When…”
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IS6110-5′3′FP: an automated typing approach for Mycobacterium tuberculosis complex strains simultaneously targeting and resolving IS6110 5′ and 3′ polymorphisms by Thabet, Sara, Karboul, Anis, Dekhil, Neira, Mardassi, Helmi

“…Fingerprinting of Mycobacterium tuberculosis complex strains based on the IS6110 insertion sequence would considerably gain in terms of discriminatory power…”
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HBHA-IGRA and cytotoxic mediators release assays for the diagnosis of cervical tuberculous lymphadenitis by Bchiri, Soumaya, Bouzekri, Asma, Ouni, Rym, Lahiani, Rim, Romdhane, Emna, Dekhil, Neira, Ben Hamouda, Sonia, Mardassi, Helmi, Ferjani, Asma, Petit, Emanuelle, Corbière, Véronique, Rammeh, Soumaya, Mascart, Françoise, Locht, Camille, Ben Salah, Mamia, Barbouche, Mohamed Ridha, Benabdessalem, Chaouki

“…Cervical tuberculous lymphadenitis (CTL), the most frequent extrapulmonary form of tuberculosis, is currently a major health problem in Tunisia and in several…”
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Frequent Homologous Recombination Events in Mycobacterium tuberculosis PE/PPE Multigene Families: Potential Role in Antigenic Variability by KARBOUL, Anis, MAZZA, Alberto, GEY VAN PITTIUS, Nicolaas C, HO, John L, BROUSSEAU, Roland, MARDASSI, Helmi

“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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High Frequency of Enterocytozoon bieneusi Genotype WL12 Occurrence among Immunocompromised Patients with Intestinal Microsporidiosis by Messaoud, Mariem, Abbes, Salma, Gnaien, Mayssa, Rebai, Yasmine, Kallel, Aicha, Jemel, Sana, Cherif, Ghaya, Skhairia, Mohamed Amine, Marouen, Sonia, Fakhfekh, Najla, Mardassi, Helmi, Belhadj, Slaheddine, Znaidi, Sadri, Kallel, Kalthoum

“…Microsporidiosis is an emerging opportunistic infection causing severe digestive disorders in immunocompromised patients. The aim of this study was to…”
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Intracellular Synthesis, Processing, and Transport of Proteins Encoded by ORFs 5 to 7 of Porcine Reproductive and Respiratory Syndrome Virus by Mardassi, Helmi, Massie, Bernard, Dea, Serge

“…Porcine Reproductive and Respiratory Syndrome Virus (PRRSV), a small enveloped virus containing a positive-strand RNA genome, possesses at least three major…”
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Tuberculosis due to resistant Haarlem strain, Tunisia by Mardassi, Helmi, Namouchi, Amine, Haltiti, Raja, Zarrouk, Mourad, Mhenni, Besma, Karboul, Anis, Khabouchi, Neila, Gey van Pittius, Nico C, Streicher, Elizabeth M, Rauzier, Jean, Gicquel, Brigette, Dellagi, Koussay

“…Multidrug-resistant tuberculosis was diagnosed in 21 HIV-negative, nonhospitalized male patients residing in northern Tunisia. A detailed investigation showed…”
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Insights into the evolutionary history of tubercle bacilli as disclosed by genetic rearrangements within a PE_PGRS duplicated gene pair by Karboul, Anis, Gey van Pittius, Nicolaas C, Namouchi, Amine, Vincent, Véronique, Sola, Christophe, Rastogi, Nalin, Suffys, Philip, Fabre, Michel, Cataldi, Angel, Huard, Richard C, Kurepina, Natalia, Kreiswirth, Barry, Ho, John L, Gutierrez, M Cristina, Mardassi, Helmi

“…The highly homologous PE_PGRS (Proline-glutamic acid_polymorphic GC-rich repetitive sequence) genes are members of the PE multigene family which is found only…”
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