Search Results - "MARCINIAK, R. A"

Sir2: an NAD-dependent histone deacetylase that connects chromatin silencing, metabolism, and aging by Imai, S, Johnson, F B, Marciniak, R A, McVey, M, Park, P U, Guarente, L

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HIV‐1 Tat protein promotes formation of more‐processive elongation complexes by Marciniak, R.A., Sharp, P.A.

“…The Tat protein of HIV‐1 trans‐activates transcription in vitro in a cell‐free extract of HeLa nuclei. Quantitative analysis of the efficiency of elongation…”
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Identification and Characterization of a HeLa Nuclear Protein that Specifically Binds to the Trans-Activation-Response (TAR) Element of Human Immunodeficiency Virus by Marciniak, Robert A., Garcia-Blanco, Mariano A., Sharp, Phillip A.

“…Human immunodeficiency virus type 1 RNAs contain a sequence, trans-activation-response (TAR) element, which is required for tat protein-mediated…”
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Targeted gene therapy for breast cancer with truncated Bid by Kazhdan, I, Long, L, Montellano, R, Cavazos, D A, Marciniak, R A

“…We studied the efficiency of the proapoptotic factor tBid, targeted to tumor cells using the promoters of the hTERT, Survivin and Muc1 genes, in killing breast…”
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Dyskeratosis congenita, telomeres and human ageing by MARCINIAK, R. A, JOHNSON, F. B, GUARENTE, L

“…As normal humans age, telomeres shorten in tissues that contain dividing cells, and this has been proposed both as a cause of ageing and as a tumor-suppressor…”
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HIV TAR: an RNA enhancer? by Sharp, P A, Marciniak, R A

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The Saccharomyces cerevisiae WRN homolog Sgs1p participates in telomere maintenance in cells lacking telomerase by Johnson, F. Brad, Marciniak, Robert A., McVey, Mitch, Stewart, Sheila A., Hahn, William C., Guarente, Leonard

“…Werner syndrome (WS) is marked by early onset of features resembling aging, and is caused by loss of the RecQ family DNA helicase WRN. Precisely how loss of…”
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Nuclear Structure in Normal and Bloom Syndrome Cells by Yankiwski, Victor, Marciniak, Robert A., Guarente, Leonard, Neff, Norma F.

“…Bloom syndrome (BS) is a rare cancer-predisposing disorder in which the cells of affected persons have a high frequency of somatic mutation and genomic…”
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Association of the bloom syndrome protein with topoisomerase IIIα in somatic and meiotic cells by JOHNSON, F. B, LOMBARD, D. B, NEFF, N. F, MASTRANGELO, M.-A, DEWOLF, W, ELLIS, N. A, MARCINIAK, R. A, YIZHONG YIN, JAENISCH, R, GUARENTE, L

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Mutations in the WRN Gene in Mice Accelerate Mortality in a p53-Null Background by Lombard, David B., Beard, Caroline, Johnson, Brad, Marciniak, Robert A., Dausman, Jessie, Bronson, Roderick, Buhlmann, Janet E., Lipman, Ruth, Curry, Ruth, Sharpe, Arlene, Jaenisch, Rudolf, Guarente, Leonard

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Nucleolar Localization of the Werner Syndrome Protein in Human Cells by Marciniak, Robert A., Lombard, David B., Johnson, F. Bradley, Guarente, Leonard

“…Werner Syndrome (WS) is a human genetic disorder with many features of premature aging. The gene defective in WS (WRN) has been cloned and encodes a protein…”
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HIV-1 Tat protein trans-activates transcription in vitro by Marciniak, R A, Calnan, B J, Frankel, A D, Sharp, P A

“…Tat protein of human immunodeficiency virus 1 is a potent trans-activator of viral gene expression. We show that purified Tat protein stimulates transcription…”
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Death receptor 4 (DR4) efficiently kills breast cancer cells irrespective of their sensitivity to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) by Kazhdan, Irene, Marciniak, Robert A

“…Breast cancer cells are generally resistant to induction of apoptosis by treatment with tumor necrosis factor-related apoptosis-inducing ligand (TRAIL). In…”
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Geographic classification of dengue-2 virus strains by antigen signature analysis by Monath, T P, Wands, J R, Hill, L J, Brown, N V, Marciniak, R A, Wong, M A, Gentry, M K, Burke, D S, Grant, J A, Trent, D W

“…Dengue-2 virus strains from different locations were compared by T1-RNAse-resistant oligonucleotide fingerprinting and antigen signature analysis. The latter…”
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Telomeres, the nucleolus and aging by Johnson, F Brad, Marciniak, Robert A, Guarente, Leonard

“…Reactivation of telomerase in cultured human cells extends their replicative life span beyond the Hayflick limit. How telomere shortening triggers cell…”
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Structural analysis of hepatitis B surface antigen by monoclonal antibodies by BEN-PORATH, E, WANDS, J. R, MARCINIAK, R. A, WONG, M. A, HORNSTEIN, L, RYDER, R, CANLAS, M, LINGAO, A, ISSELBACHER, K. J

“…A method has been developed for the analysis of hepatitis B surface antigen (HBsAg) antigenic structure at the molecular level that creates "fingerprints" or…”
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Hepatitis B Viral Antigenic Structure: Signature Analysis by Monoclonal Radioimmunoassays by Wands, Jack R., Wong, M. Anthony, Shorey, James, Brown, Russell D., Marciniak, Robert A., Isselbacher, Kurt J.

“…An approach has been developed for the analysis of hepatitis B viral (HBV) antigenic structure that creates numerical ``signatures'' of HBV strains. This…”
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Quantitative Removal of Hepatitis B Viral Antigens from Serum by a Monoclonal IgM Coupled to a Biocompatible Solid-Phase Support by Marciniak, Robert A., Wands, Jack R., Bruns, Romaine R., Malchesky, Paul S., Nose, Yukihiko, Haber, Edgar

“…We covalently linked to regenerated cellulose filters a high-affinity monoclonal IgM produced against epitopes that reside on hepatitis B viral surface antigen…”
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Demonstration of previously undetected hepatitis B viral determinants in an Australian Aboriginal population by monoclonal anti-hbs antibody radioimmunoassays by Wands, J R, Marciniak, R A, Isselbacher, K J, Varghese, M, Don, G, Halliday, J W, Powell, L W

“…High-affinity IgM and IgG monoclonal antibodies (anti-HBs) against hepatitis B surface antigen (HBsAg) determinants were used to study a confined Australian…”
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Dual Luciferase Assay System for Rapid Assessment of Gene Expression in Saccharomyces cerevisiae by McNabb, David S, Reed, Robin, Marciniak, Robert A

“…Classifications Services EC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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