Search Results - "MARCINEK, D. J"

Horizontal movements and depth distribution of large adult yellowfin tuna ( Thunnus albacares ) near the Hawaiian Islands, recorded using ultrasonic telemetry: implications for the physiological ecology of pelagic fishes by Brill, R W, Block, BA, Boggs, CH, Bigelow, KA, Freund, E V, Marcinek, D J

“…We measured the horizontal and vertical movements of five adult yellowfin tuna (Thunnus albacares, estimated body mass 64 to 93 kg) near the main Hawaiian…”
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Mitochondrial-Targeted Catalase: Extended Longevity and the Roles in Various Disease Models by Dai, D-F, Chiao, Y-A, Martin, G M, Marcinek, D J, Basisty, N, Quarles, E K, Rabinovitch, P S

“…The free-radical theory of aging was proposed more than 50 years ago. As one of the most popular mechanisms explaining the aging process, it has been…”
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Environmental preferences of yellowfin tuna (Thunnus albacares) at the northern extent of its range by BLOCK, B. A, KEEN, J. E, CASTILLO, B, DEWAR, H, FREUND, E. V, MARCINEK, D. J, BRILL, R. W, FARWELL, C

“…We used acoustic telemetry to examine the small-scale movement patterns of yellowfin tuna (Thunnus albacares) in the California Bight at the northern extent of…”
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Mitochondrial dysfunction measured in vivo by Marcinek, D. J.

“…Aims:  Mitochondria are responsible for meeting the majority of the energetic demand of most tissues. They also play a major role in regulating cell survival…”
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In Vivo Metabolic Spectroscopy Identifies Deficits in Mitochondrial Quality and Capacity in Aging Skeletal Muscle by Marcinek, D J, Conley, K E

“…In vivo metabolic spectroscopy provides the opportunity to probe mitochondrial dysfunction in vivo with the rigor previously limited to in vitro studies. In…”
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Depth and muscle temperature of Pacific bluefin tuna examined with acoustic and pop-up satellite archival tags by MARCINEK, David J, BLACKWELL, Susanna B, DEWAR, Heidi, FREUND, Ellen V, FARWELL, Charles, DAU, Daniel, SEITZ, Andrew C, BLOCK, Barbara A

“…Six Pacific bluefin tuna were tracked with ultrasonic telemetry and two with pop-up satellite archival tags (PSATs) in the eastern Pacific Ocean in 1997, 1998,…”
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Extensive characterisation of advanced manufacturing solutions for the ITER Central Solenoid pre-compression system by Langeslag, S.A.E., Sgobba, S., Libeyre, P., Marcinek, D.J., Zhang, Z.

“…The ITER Central Solenoid (CS), positioned in the center of the ITER tokamak, will provide a magnetic field, contributing to the confinement of the plasma. The…”
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Oxygen affinity and amino acid sequence of myoglobins from endothermic and ectothermic fish by Marcinek, D J, Bonaventura, J, Wittenberg, J B, Block, B A

“…Myoglobin (Mb) buffers intracellular O2 and facilitates diffusion of O2 through the cell. These functions of Mb will be most effective when intracellular PO2…”
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THE ROLE OF MITOCHONDRIAL ENERGETICS IN CARDIAC AND SKELETAL MUSCLE AGING by Rabinovitch, P, Marcinek, D J

“…Aging in both man and mouse is associated with significant declines in skeletal and cardiac muscle function, even in otherwise healthy individuals. We have…”
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Defects in mitochondrial localization and ATP synthesis in the mdx mouse model of Duchenne muscular dystrophy are not alleviated by PDE5 inhibition by Percival, Justin M, Siegel, Michael P, Knowels, Gary, Marcinek, David J

“…Given the crucial roles for mitochondria in ATP energy supply, Ca(2+) handling and cell death, mitochondrial dysfunction has long been suspected to be an…”
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Mitochondrial‐targeted peptide rapidly improves mitochondrial energetics and skeletal muscle performance in aged mice by Siegel, Michael P., Kruse, Shane E., Percival, Justin M., Goh, Jorming, White, Collin C., Hopkins, Heather C., Kavanagh, Terrance J., Szeto, Hazel H., Rabinovitch, Peter S., Marcinek, David J.

“…Summary Mitochondrial dysfunction plays a key pathogenic role in aging skeletal muscle resulting in significant healthcare costs in the developed world…”
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A comparative assessment of metallurgical and mechanical properties of two austenitic stainless steels for the conductor jacket of the ITER Central Solenoid by Sgobba, Stefano, Libeyre, Paul, Marcinek, Dawid Jaroslaw, Nyilas, Arman

“…When energized, the ITER Central Solenoid (CS) coils will experience large cyclic electromagnetic forces that the conductor jacket itself must withstand. The…”
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Progress in Production and Qualification of Stainless Steel Jacket Material for the Conductor of the ITER Central Solenoid by Sgobba, S., Dalin, J., Libeyre, P., Marcinek, D. J., Nyilas, A.

“…When energized, the ITER Central Solenoid coils experience large pulsed electromagnetic forces that the conductor jacket itself must withstand. The conductor…”
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Mitochondrial dysfunction: impact on exercise performance and cellular aging by Conley, Kevin E, Jubrias, Sharon A, Amara, Catherine E, Marcinek, David J

“…Innovative noninvasive methods open a new window on the cell in vivo. This window reveals that the tempo of mitochondrial dysfunction with age varies among…”
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Reduced mitochondrial coupling in vivo alters cellular energetics in aged mouse skeletal muscle by Marcinek, David J., Schenkman, Kenneth A., Ciesielski, Wayne A., Lee, Donghoon, Conley, Kevin E.

“…The mitochondrial theory of ageing proposes that the accumulation of oxidative damage to mitochondria leads to mitochondrial dysfunction and tissue…”
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Mitochondrial coupling in vivo in mouse skeletal muscle by Marcinek, David J, Schenkman, Kenneth A, Ciesielski, Wayne A, Conley, Kevin E

“…The coupling of mitochondrial ATP synthesis and oxygen consumption (ratio of ATP and oxygen fluxes, P/O) plays a central role in cellular bioenergetics…”
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Second Annual Huntington Disease Clinical Research Symposium: Organized by the Huntington Study Group by Sabine, Charles, Trembath, K., Churchyard, A., Horton, Z., Tippett, L., Hogg, V., Roxburgh, R., Velakoulis, D., Delatycki, M., Aylward, E., Nopoulos, P., Johnson, H., Juhl, A., Magnotta, V., Pierson, R., Langbehn, D., Ross, C., Paulsen, J., Maltby, Lewis, Poston, K. L., Tang, C., Feigin, A., Ma, Y., Guttman, M., Paulsen, J. S., Dhawan, V., Eidelberg, D., Katz, Russell, Goodman, L. Veatch, Lovecky, D., Quaid, K., Goh, A., Yastrubetskaya, O., Chiu, E., Evans, K., Anderson, K., Borowsky, B., Duff, K., Ho, A., Sills, T., Vaccarino, A., Van Kammen, D., Block, R. C., Dorsey, E. R., Beck, C. A., Shoulson, I., Pirogovsky, E., Bartlett, B., Goldstein, J., Peavy, G., Jacobson, M., Corey-Bloom, J., Gilbert, P., Lessig, S., Peavy, G. M., Weaver, K. E., Richards, T. L., Liang, O., Aylward, E. H., Beglinger, L. J., Adams, W. H., Paulson, H., Fiedorowicz, J. G., Langbehn, D. R., Leserman, A., Conley, K. E., Jubrias, S., Amara, C., Shankland, E., Marcinek, D. J., O’Rourke, J. F., Wang, C., Rowe, K., Kloos, A. D., Kegelmeyer, D. A., Kostyk, S. K., Chua, P., Desmond, P., Christensen, S., Steward, C., Judd, F., Lloyd, J., Tress, B., Pugliese, M., Phan, P., Sanchez-Ramos, J., Oster, E., Bausch, J., Shinaman, A., Kayson, E., Oakes, D., Oelke, L., Butterfield, L., Cimino, C., McCall, M., Ling, L., Stell, B., Annis, J., Cha, J., Como, P.

“…Issue Title: Multifunctional Drugs as Neurotherapeutics…”
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Oxygen regulation and limitation to cellular respiration in mouse skeletal muscle in vivo by Marcinek, David J, Ciesielski, Wayne A, Conley, Kevin E, Schenkman, Kenneth A

“…In skeletal muscle, intracellular Po2 can fall to as low as 2-3 mmHg. This study tested whether oxygen regulates cellular respiration in this range of oxygen…”
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Basal glycogenolysis in mouse skeletal muscle: in vitro model predicts in vivo fluxes by Lambeth, Melissa J., Kushmerick, Martin J., Marcinek, David J., Conley, Kevin E.

“…A previously published mammalian kinetic model of skeletal muscle glycogenolysis, consisting of literature in vitro parameters, was modified by substituting…”
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