Search Results - "MARCHESI, Federica"

Macrophages as tools and targets in cancer therapy by Mantovani, Alberto, Allavena, Paola, Marchesi, Federica, Garlanda, Cecilia

“…Tumour-associated macrophages are an essential component of the tumour microenvironment and have a role in the orchestration of angiogenesis, extracellular…”
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Tumor-associated myeloid cells: diversity and therapeutic targeting by Mantovani, Alberto, Marchesi, Federica, Jaillon, Sebastien, Garlanda, Cecilia, Allavena, Paola

“…Myeloid cells in tumor tissues constitute a dynamic immune population characterized by a non-uniform phenotype and diverse functional activities. Both…”
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Molecular mechanisms of perineural invasion, a forgotten pathway of dissemination and metastasis by Marchesi, Federica, Piemonti, Lorenzo, Mantovani, Alberto, Allavena, Paola

“…Abstract Invasion and metastasis are key components of cancer progression. Inflammatory mediators, including cytokines and chemokines, can facilitate tumor…”
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Cancer‐promoting tumor‐associated macrophages: New vistas and open questions by Mantovani, Alberto, Germano, Giovanni, Marchesi, Federica, Locatelli, Marco, Biswas, Subhra K.

“…Tumor‐associated macrophages (TAMs) are key components of the tumor macroenvironment. Cancer‐ and host cell‐derived signals generally drive the functions of…”
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IL-10 and Macrophages Orchestrate Gut Homeostasis by Mantovani, Alberto, Marchesi, Federica

“…Macrophages in the gut originate from blood precursors and have distinct functional properties. In this issue of Immunity,Zigmond et al. (2014) and Shouval…”
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Immune cells: plastic players along colorectal cancer progression by Di Caro, Giuseppe, Marchesi, Federica, Laghi, Luigi, Grizzi, Fabio

“…Inflammatory cells are involved in tumour initiation and progression. In parallel, the adaptive immune response plays a key role in fighting tumour growth and…”
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Spatial distribution of B cells predicts prognosis in human pancreatic adenocarcinoma by Castino, Giovanni Francesco, Cortese, Nina, Capretti, Giovanni, Serio, Simone, Di Caro, Giuseppe, Mineri, Rossana, Magrini, Elena, Grizzi, Fabio, Cappello, Paola, Novelli, Francesco, Spaggiari, Paola, Roncalli, Massimo, Ridolfi, Cristina, Gavazzi, Francesca, Zerbi, Alessandro, Allavena, Paola, Marchesi, Federica

“…B-cell responses are emerging as critical regulators of cancer progression. In this study, we investigated the role of B lymphocytes in the microenvironment of…”
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Bone Marrow Mesenchymal Stromal Cells Drive Protective M2 Microglia Polarization After Brain Trauma by Zanier, Elisa R., Pischiutta, Francesca, Riganti, Loredana, Marchesi, Federica, Turola, Elena, Fumagalli, Stefano, Perego, Carlo, Parotto, Emanuela, Vinci, Paola, Veglianese, Pietro, D’Amico, Giovanna, Verderio, Claudia, De Simoni, Maria-Grazia

“…Microglia/macrophages (M) are major contributors to postinjury inflammation, but they may also promote brain repair in response to specific environmental…”
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The Impact of Molecular Subtyping on Pathological Staging of Pancreatic Cancer by Dreyer, Stephan B, Rae, Sarah, Bisset, Kirsty, Upstill-Goddard, Rosie, Gemenetzis, Georgios, Johns, Amber L, Dickson, Euan J, Mittal, Anubhav, Gill, Anthony J, Duthie, Fraser, Pea, Antonio, Lawlor, Rita T, Scarpa, Aldo, Salvia, Roberto, Pulvirenti, Alessandra, Zerbi, Alessandro, Marchesi, Federica, McKay, Colin J, Biankin, Andrew V, Samra, Jaswinder S, Chang, David K, Jamieson, Nigel B

“…The long-term outcomes following surgical resection for pancreatic ductal adenocarcinoma (PDAC) remains poor, with only 20% of patients surviving 5 years after…”
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Heterogeneity of Colorectal Cancer Progression: Molecular Gas and Brakes by Gaiani, Federica, Marchesi, Federica, Negri, Francesca, Greco, Luana, Malesci, Alberto, de’Angelis, Gian Luigi, Laghi, Luigi

“…The review begins with molecular genetics, which hit the field unveiling the involvement of oncogenes and tumor suppressor genes in the pathogenesis of…”
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Tumor-associated macrophages and response to 5-fluorouracil adjuvant therapy in stage III colorectal cancer by Malesci, Alberto, Bianchi, Paolo, Celesti, Giuseppe, Basso, Gianluca, Marchesi, Federica, Grizzi, Fabio, Di Caro, Giuseppe, Cavalleri, Tommaso, Rimassa, Lorenza, Palmqvist, Richard, Lugli, Alessandro, Koelzer, Viktor. H., Roncalli, Massimo, Mantovani, Alberto, Ogino, Shuji, Laghi, Luigi

“…Tumor-associated macrophages (TAMs) play a role in tumor development and progression. We hypothesized that abundance of TAMs might modify efficacy of…”
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Multiplexed Imaging Mass Cytometry Analysis in Preclinical Models of Pancreatic Cancer by Erreni, Marco, Fumagalli, Maria Rita, Zanini, Damiano, Candiello, Ermes, Tiberi, Giorgia, Parente, Raffaella, D'Anna, Raffaella, Magrini, Elena, Marchesi, Federica, Cappello, Paola, Doni, Andrea

“…Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal cancers. PDAC is characterized by a complex tumor microenvironment (TME), that plays a…”
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Distinct responses of newly identified monocyte subsets to advanced gastrointestinal cancer and COVID-19 by Rigamonti, Alessandra, Castagna, Alessandra, Viatore, Marika, Colombo, Federico Simone, Terzoli, Sara, Peano, Clelia, Marchesi, Federica, Locati, Massimo

“…Monocytes are critical cells of the immune system but their role as effectors is relatively poorly understood, as they have long been considered only as…”
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Circulating Inflammatory Mediators as Potential Prognostic Markers of Human Colorectal Cancer by Di Caro, Giuseppe, Carvello, Michele, Pesce, Samantha, Erreni, Marco, Marchesi, Federica, Todoric, Jelena, Sacchi, Matteo, Montorsi, Marco, Allavena, Paola, Spinelli, Antonino

“…Cytokines and chemokines in the tumor microenvironment drive metastatic development and their serum levels might mirror the ongoing inflammatory reaction at…”
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Clinical frailty scale as a predictor of outcome in elderly patients affected by moderate or severe traumatic brain injury by Zacchetti, Lucia, Longhi, Luca, Zangari, Rosalia, Aresi, Silvia, Marchesi, Federica, Gritti, Paolo, Biroli, Francesco, Lorini, Luca Ferdinando

“…Older age is a well-known risk factor for unfavorable outcome in traumatic brain injury (TBI). However, many older people with TBI respond well to aggressive…”
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Role of CX3CR1/CX3CL1 axis in primary and secondary involvement of the nervous system by cancer by Marchesi, Federica, Locatelli, Marco, Solinas, Graziella, Erreni, Marco, Allavena, Paola, Mantovani, Alberto

“…Abstract CX3CL1 or Fractalkine is a peculiar chemokine that can exist either in a soluble form, like all the other chemokines, and as a cell membrane molecule…”
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Bone marrow mesenchymal stem cells express a restricted set of functionally active chemokine receptors capable of promoting migration to pancreatic islets by Sordi, Valeria, Malosio, Maria Luisa, Marchesi, Federica, Mercalli, Alessia, Melzi, Raffaella, Giordano, Tiziana, Belmonte, Nathalie, Ferrari, Giuliana, Leone, Biagio Eugenio, Bertuzzi, Federico, Zerbini, Gianpaolo, Allavena, Paola, Bonifacio, Ezio, Piemonti, Lorenzo

“…Bone marrow–derived mesenchymal stem cells (BM-MSCs) are stromal cells with the ability to proliferate and differentiate into many tissues. Although they…”
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The Fractalkine-Receptor Axis Improves Human Colorectal Cancer Prognosis by Limiting Tumor Metastatic Dissemination by Erreni, Marco, Siddiqui, Imran, Marelli, Giulia, Grizzi, Fabio, Bianchi, Paolo, Morone, Diego, Marchesi, Federica, Celesti, Giuseppe, Pesce, Samantha, Doni, Andrea, Rumio, Cristiano, Roncalli, Massimo G, Laghi, Luigi, Mantovani, Alberto, Allavena, Paola

“…Human colorectal cancer (CRC) is a frequent neoplasia in Western countries, and its metastatic progression is a major cause of cancer-related death. In search…”
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Increased survival, proliferation, and migration in metastatic human pancreatic tumor cells expressing functional CXCR4 by MARCHESI, Federica, MONTI, Paolo, LEONE, Biagio Eugenio, ZERBI, Alessandro, VECCHI, Annunciata, PIEMONTI, Lorenzo, MANTOVANI, Alberto, ALLAVENA, Paola

“…In this study, we have evaluated 11 pancreatic tumor cell lines and tumor cells from surgical samples of patients with pancreatic adenocarcinoma for expression…”
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The chemokine receptor CX3CR1 is involved in the neural tropism and malignant behavior of pancreatic ductal adenocarcinoma by Marchesi, Federica, Piemonti, Lorenzo, Fedele, Giuseppe, Destro, Annarita, Roncalli, Massimo, Albarello, Luca, Doglioni, Claudio, Anselmo, Achille, Doni, Andrea, Bianchi, Paolo, Laghi, Luigi, Malesci, Alberto, Cervo, Luigi, Malosio, Marialuisa, Reni, Michele, Zerbi, Alessandro, Di Carlo, Valerio, Mantovani, Alberto, Allavena, Paola

“…Tumor perineural dissemination is a hallmark of human pancreatic ductal adenocarcinoma (PDAC) and represents a major source of local tumor recurrence after…”
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