Search Results - "MARC, JANJA"
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1
Roles of Non-Canonical Wnt Signalling Pathways in Bone Biology
Published in International journal of molecular sciences (07-10-2021)“…The Wnt signalling pathway is one of the central signalling pathways in bone development, homeostasis and regulation of bone mineral density. It consists of…”
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2
Glucocorticoid Receptor Regulates TNFSF11 Transcription by Binding to Glucocorticoid Responsive Element in TNFSF11 Proximal Promoter Region
Published in International journal of molecular sciences (21-01-2021)“…Glucocorticoid osteoporosis is a serious side effect of long term glucocorticoid uptake and it is caused by osteoblast apoptosis and imbalance in the major…”
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3
Epigenetic enzymes influenced by oxidative stress and hypoxia mimetic in osteoblasts are differentially expressed in patients with osteoporosis and osteoarthritis
Published in Scientific reports (01-11-2018)“…Epigenetic mechanisms including posttranslational histone modifications and DNA methylation are emerging as important determinants of bone homeostasis. With…”
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4
PPIA, HRPT1, and PGK1 genes as the appropriate combination for RT-qPCR normalization in alveolar and femoral bone remodeling in olanzapine-treated rats
Published in Acta pharmaceutica (Zagreb, Croatia) (01-09-2024)“…Reliable gene expression analysis in bone remodeling studies requires an appropriate selection of internal controls, stable reference genes for the…”
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5
Osteoimmunology and the influence of pro-inflammatory cytokines on osteoclasts
Published in Biochemia medica (01-01-2013)“…Bone and immune system are functionally interconnected. Immune and bone cells derive from same progenitors in the bone marrow, they share a common…”
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6
Towards an enhanced understanding of osteoanabolic effects of PTH-induced microRNAs on osteoblasts using a bioinformatic approach
Published in Frontiers in endocrinology (Lausanne) (17-07-2024)“…In this study, we used a bioinformatic approach to construct a miRNA-target gene interaction network potentially involved in the anabolic effect of parathyroid…”
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7
Reference intervals of 24 trace elements in blood, plasma and erythrocytes for the Slovenian adult population
Published in Clinical chemistry and laboratory medicine (25-04-2024)“…The aim of the present study was to establish the population- and laboratory-specific reference intervals (RIs) for the Slovenian adult population for 24 trace…”
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8
Mesenchymal Stem Cells in the Musculoskeletal System: From Animal Models to Human Tissue Regeneration?
Published in Stem cell reviews (01-06-2018)“…The musculoskeletal system includes tissues that have remarkable regenerative capabilities. Bone and muscle sustain micro-damage throughout the lifetime, yet…”
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9
The relationship between osteoclastogenic and anti-osteoclastogenic pro-inflammatory cytokines differs in human osteoporotic and osteoarthritic bone tissues
Published in Journal of biomedical science (01-03-2012)“…Pro-inflammatory cytokines possess osteoclastogenic or anti-osteoclastogenic activities. They influence osteoclasts directly or via the receptor activator of…”
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10
Interactome of PTH-Regulated miRNAs and Their Predicted Target Genes for Investigating the Epigenetic Effects of PTH (1–34) in Bone Metabolism
Published in Genes (13-08-2022)“…Osteoporosis is a metabolic bone disease that mostly affects the elderly. A lot of drugs are available, mostly with an antiresorptive effect but just a few…”
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11
Molecular mechanisms of insulin resistance and associated diseases
Published in Clinica chimica acta (2007)“…Insulin resistance is a state in which higher than normal concentrations of insulin are required for normal response. The most common underlying cause is…”
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12
Genome-wide association study identifies genetic variants which predict the response of bone mineral density to teriparatide therapy
Published in Annals of the rheumatic diseases (01-07-2023)“…Teriparatide (TPTD) is an effective treatment for osteoporosis but the individual response to therapy is variable for reasons that are unclear. This study…”
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13
COVID-19 Vaccines Safety Tracking (CoVaST): Protocol of a Multi-Center Prospective Cohort Study for Active Surveillance of COVID-19 Vaccines' Side Effects
Published in International journal of environmental research and public health (25-07-2021)“…Coronavirus disease (COVID-19) vaccine-related side effects have a determinant role in the public decision regarding vaccination. Therefore, this study has…”
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14
TBP , PPIA , YWHAZ and EF1A1 Are the Most Stably Expressed Genes during Osteogenic Differentiation
Published in International journal of molecular sciences (12-04-2022)“…RT-qPCR is the gold standard and the most commonly used method for measuring gene expression. Selection of appropriate reference gene(s) for normalization is a…”
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15
Bone microRNAs and Ageing
Published in Current pharmaceutical biotechnology (01-03-2017)“…The decline of tissue function in ageing is a consequence of many changes in the gene expression and other extrinsic factors. The molecular mechanisms…”
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16
Personalized laboratory medicine: a patient-centered future approach
Published in Clinical chemistry and laboratory medicine (27-11-2018)“…In contrast to population-based medical decision making, which emphasizes the use of evidence-based treatment strategies for groups of patients, personalized…”
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17
Trace elements and APOE polymorphisms in pregnant women and their new-borns
Published in Environment international (01-10-2020)“…[Display omitted] •17% and 20% APOE ε4 carriers were identified among mothers and new-borns.•Mothers carrying APOE ε4 had higher Hg, As in venous and cord…”
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18
Association of FTO gene variant (rs8050136) with type 2 diabetes and markers of obesity, glycaemic control and inflammation
Published in Journal of medical biochemistry (01-04-2019)“…, a gene recently discovered in genomewide associated studies for type 2 diabetes mellitus (T2D), play an important role in the management of energy…”
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19
Expression of bone resorption genes in osteoarthritis and in osteoporosis
Published in Journal of bone and mineral metabolism (01-07-2007)“…Cathepsin K and MMP-9 are considered to be the most abundant proteases in osteoclasts. TRAP is a marker for osteoclasts, and there is increasing evidence of…”
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20
Redox Status and Telomere–Telomerase System Biomarkers in Patients with Acute Myocardial Infarction Using a Principal Component Analysis: Is There a Link?
Published in International journal of molecular sciences (01-09-2023)“…In the present study, we examined redox status parameters in arterial and venous blood samples, its potential to predict the prognosis of acute myocardial…”
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