Search Results - "MANVELYAN, MARINA"

Small Supernumerary Marker Chromosomes and Uniparental Disomy Have a Story to Tell by Liehr, Thomas, Ewers, Elisabeth, Hamid, Ahmed B., Kosyakova, Nadezda, Voigt, Martin, Weise, Anja, Manvelyan, Marina

“…Small supernumerary maker chromosomes (sSMC) and uniparental disomy (UPD) are rare, and a combination of both is rarely encountered. Accordingly, only 46 sSMC…”
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Early embryonic chromosome instability results in stable mosaic pattern in human tissues by Mkrtchyan, Hasmik, Gross, Madeleine, Hinreiner, Sophie, Polytiko, Anna, Manvelyan, Marina, Mrasek, Kristin, Kosyakova, Nadezda, Ewers, Elisabeth, Nelle, Heike, Liehr, Thomas, Volleth, Marianne, Weise, Anja

“…The discovery of copy number variations (CNV) in the human genome opened new perspectives on the study of the genetic causes of inherited disorders and the…”
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Chromosome distribution in human sperm - a 3D multicolor banding-study by Manvelyan, Marina, Hunstig, Friederike, Bhatt, Samarth, Mrasek, Kristin, Pellestor, Franck, Weise, Anja, Simonyan, Isabella, Aroutiounian, Rouben, Liehr, Thomas

“…Nuclear architecture studies in human sperm are sparse. By now performed ones were practically all done on flattened nuclei. Thus, studies close at the in vivo…”
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The Human Genome Puzzle - the Role of Copy Number Variation in Somatic Mosaicism by Mkrtchyan, Hasmik, Gross, Madeleine, Hinreiner, Sophie, Polytiko, Anna, Manvelyan, Marina, Mrasek, Kristin, Kosyakova, Nadezda, Ewers, Elisabeth, Nelle, Heike, Liehr, Thomas, Bhatt, Samarth, Thoma, Karen, Gebhart, Erich, Wilhelm, Sylvia, Fahsold, Raimund, Volleth, Marianne, Weise, Anja

“…The discovery of copy number variations (CNV) in the human genome opened new perspectives in the study of the genetic causes of inherited disorders and the…”
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Centromeric association of small supernumerary marker chromosomes with their sister-chromosomes detected by three dimensional molecular cytogenetics by Klein, Elisabeth, Manvelyan, Marina, Simonyan, Isabella, Hamid, Ahmed B, Guilherme, Roberta Santos, Liehr, Thomas, Karamysheva, Tatyana

“…Small supernumerary marker chromosomes (sSMC) are detected in 0.043% of general population and can be characterized for their chromosomal origin, genetic…”
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New cytogenetically visible copy number variant in region 8q21.2 by Manvelyan, Marina, Cremer, Friedrich W, Lancé, Jeannette, Kläs, Rüdiger, Kelbova, Christina, Ramel, Christian, Reichenbach, Herbert, Schmidt, Catharina, Ewers, Elisabeth, Kreskowski, Katharina, Ziegler, Monika, Kosyakova, Nadezda, Liehr, Thomas

“…Cytogenetically visible unbalanced chromosomal abnormalities (UBCA), reported for >50 euchromatic regions of almost all human autosomes, are comprised of a few…”
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Position of chromosomes 18, 19, 21 and 22 in 3D-preserved interphase nuclei of human and gorilla and white hand gibbon by Manvelyan, Marina, Hunstig, Friederike, Mrasek, Kristin, Bhatt, Samarth, Pellestor, Franck, Weise, Anja, Liehr, Thomas

“…Even though comparative nuclear architecture studies in hominoids are sparse, nuclear chromosome architecture was shown to be conserved during hominoid…”
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An unusual T-cell childhood acute lymphoblastic leukemia harboring a yet unreported near-tetraploid karyotype by Garcia, Daniela Rn, Bhatt, Samarth, Manvelyan, Marina, de Souza, Mariana T, Binato, Renata, Aguiar, Thais F, Abdelhay, Eliana, Silva, Maria Luiza M

“…Near-tetraploid (model #81-103) and near-triploid (model #67-81) karyotypes are found in around 1% of childhood acute lymphoblastic leukemia. Due to its…”
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Does positioning of chromosomes 8 and 21 in interphase drive t(8;21) in acute myelogenous leukemia? by Othman, Moneeb, Lier, Amelie, Junker, Susann, Kempf, Philipp, Dorka, Franziska, Gebhart, Erich, Sheth, Frenny, Grygalewicz, Beata, Bhatt, Samarth, Weise, Anja, Mrasek, Kristin, Liehr, Thomas, Manvelyan, Marina

“…The impact of chromosome architecture in the formation of chromosome aberrations is a recent finding of interphase directed molecular cytogenetic studies…”
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Supraphysiological androgen levels induce cellular senescence in human prostate cancer cells through the Src-Akt pathway by Roediger, Julia, Hessenkemper, Wiebke, Bartsch, Sophie, Manvelyan, Marina, Huettner, Soeren S, Liehr, Thomas, Esmaeili, Mohsen, Foller, Susan, Petersen, Iver, Grimm, Marc-Oliver, Baniahmad, Aria

“…Prostate cancer (PCa) is the second leading cause of cancer mortality of men in Western countries. The androgen receptor (AR) and AR-agonists (androgens) are…”
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Centromere activity in dicentric small supernumerary marker chromosomes by Ewers, Elisabeth, Yoda, Kinya, Hamid, Ahmed B, Weise, Anja, Manvelyan, Marina, Liehr, Thomas

“…Twenty-five dicentric small supernumerary marker chromosomes (sSMC) derived from #13/21, #14, #15, #18, and #22 were studied by immunohistochemistry for their…”
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Two different del(5q) clones in a patient with myelodysplastic syndrome by Braulke, Friederike, Schanz, Julie, Steffens, Rainer, Liehr, Thomas, Manvelyan, Marina, Chudoba, Ilse, Haase, Detlef

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Heteromorphic variants of chromosome 9 by Kosyakova, Nadezda, Grigorian, Ani, Liehr, Thomas, Manvelyan, Marina, Simonyan, Isabella, Mkrtchyan, Hasmik, Aroutiounian, Rouben, Polityko, Anna D, Kulpanovich, Anna I, Egorova, Tatiana, Jaroshevich, Evgenia, Frolova, Alla, Shorokh, Natalia, Naumchik, Irina V, Volleth, Marianne, Schreyer, Isolde, Nelle, Heike, Stumm, Markus, Wegner, Rolf-Dieter, Reising-Ackermann, Gisela, Merkas, Martina, Brecevic, Lukretija, Martin, Thomas, Rodríguez, Laura, Bhatt, Samarth, Ziegler, Monika, Kreskowski, Katharina, Weise, Anja, Sazci, Ali, Vorsanova, Svetlana, Cioffi, Marcelo de Bello, Ergul, Emel

“…Heterochromatic variants of pericentromere of chromosome 9 are reported and discussed since decades concerning their detailed structure and clinical meaning…”
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De novo translocation involving two chromosomes in adult prolymphocytic leukemia—A rare case by Al-Achkar, Walid, Wafa, Abdulsamad, Manvelyan, Marina, Ikhtiar, Adnan, Liehr, Thomas

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Breakpoint mapping and complete analysis of meiotic segregation patterns in three men heterozygous for paracentric inversions by BHATT, Samarth, MORADKHANI, Kamran, LIEHR, Thomas, HAMAMAH, Samir, PELLESTOR, Franck, MRASEK, Kristin, PUECHBERTY, Jacques, MANVELYAN, Marina, HUNSTIG, Friederike, LEFORT, Genevieve, WEISE, Anja, LESPINASSE, James, SARDA, Pierre

“…Paracentric inversions (PAIs) are structural chromosomal rearrangements generally considered to be harmless. To date, only a few studies have been performed…”
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Thirty-two new cases with small supernumerary marker chromosomes detected in connection with fertility problems: Detailed molecular cytogenetic characterization and review of the literature by Manvelyan, Marina, Riegel, Mariluce, Santos, Monica, Fuster, Carme, Pellestor, Franck, Mazaurik, Marie-Luise, Schulze, Bernt, Polityko, Anna, Tittelbach, Hanne, Reising-Ackermann, Gisela, Belitz, Britta, Hehr, Ute, Kelbova, Christina, Volleth, Marianne, Gödde, Elisabeth, Anderson, Jasen, Küpferling, Peter, Köhler, Sigrid, Duba, Hans-Christoph, Dufke, Andreas, Aktas, Dilek, Martin, Thomas, Schreyer, Isolde, Ewers, Elisabeth, Reich, Daniela, Mrasek, Kristin, Weise, Anja, Liehr, Thomas

“…Thirty-two patients with fertility problems were identified as carriers of small supernumerary marker chromosomes (sSMC). Molecular cytogenetic techniques were…”
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A rare chronic myeloid leukemia case with Philadelphia chromosome, BCR-ABL e13a3 transcript and complex translocation involving four different chromosomes by ACHKAR, WALID AL, WAFA, ABDULSAMAD, ALI, BASHAR YOUSEF, MANVELYAN, MARINA, LIEHR, THOMAS

“…The so-called Philadelphia (Ph) chromosome is present in more than 90% of chronic myeloid leukemia (CML) patients. Around 5-10% of these patients show complex…”
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Preferred co-localization of chromosome 8 and 21 in myeloid bone marrow cells detected by three dimensional molecular cytogenetics by Manvelyan, Marina, Kempf, Philipp, Weise, Anja, Mrasek, Kristin, Heller, Anita, Lier, Amelie, Höffken, Klaus, Fricke, Hans-Jörg, Sayer, Herbert, Liehr, Thomas, Mkrtchyan, Hasmik

“…The impact of chromosome architecture in the formation of chromosome aberrations is a recent finding of interphase directed molecular cytogenetic studies. Also…”
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Two different del(5q) clones in a patient with myelodysplastic syndrome by Braulke, Friederike, Schanz, Julie, Steffens, Rainer, Liehr, Thomas, Manvelyan, Marina, Chudoba, Ilse, Haase, Detlef

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De novo translocation involving two chromosomes in adult prolymphocytic leukemia--a rare case by Al-Achkar, Walid, Wafa, Abdulsamad, Manvelyan, Marina, Ikhtiar, Adnan, Liehr, Thomas

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