Search Results - "MANNUCCI, P"

Miracle of haemophilia drugs: Personal views about a few main players by Mannucci, P. M.

“…Introduction In the second decade of the third millennium there have been dramatic developments pertaining to the availability of highly innovative drugs for…”
Get full text

Viral safety of coagulation factor concentrates: memoirs from an insider by Mannucci, P. M.

“…Summary The purpose of this essay is to recall the actions taken globally to improve the viral safety of coagulation factor concentrates, mainly in the years…”
Get full text

Is haemophilia B less severe than haemophilia A? by Mannucci, P. M., Franchini, M.

“…Summary A number of observations suggest that severe factor IX deficiency (<1%) may be less clinically severe than the corresponding factor VIII deficiency:…”
Get full text

Airborne pollution and cardiovascular disease: burden and causes of an epidemic by Mannucci, P M

Get full text

Back to the future: a recent history of haemophilia treatment by MANNUCCI, P. M.

“…In the last few decades, the management of patients with haemophilia has witnessed dramatic improvements, through the larger availability of safe…”
Get full text

Use and prescription appropriateness of drugs for peptic ulcer and gastrooesophageal reflux disease in hospitalized older people by Franchi, C, Mannucci, PM, Nobili, A, Ardoino, I

“…Purpose The aims of this study were to assess the prevalence of use and prescription appropriateness of drugs for peptic ulcer and gastrooesophageal reflux…”
Get full text

Laboratory monitoring of replacement therapy for major surgery in von Willebrand disease by Mannucci, P. M., Franchini, M.

“…Von Willebrand disease (VWD) is an inherited haemorrhagic disorder caused by a quantitative or qualitative defect of von Willebrand factor (VWF), a multimeric…”
Get full text

Venous thromboembolism in von Willebrand disease by Mannucci, P M

Get more information

A randomized clinical trial of prophylaxis in children with hemophilia A (the ESPRIT Study) by GRINGERI, A., LUNDIN, B., VON MACKENSEN, S., MANTOVANI, L., MANNUCCI, P. M.

“…Background: Prevention of arthropathy is a major goal of hemophilia treatment. While studies in adults have demonstrated an impact of prophylaxis on the…”
Get full text

Health technology assessment for pharmaceuticals in the European Union: what lessons after two decades? by Garattini, L., Bozzetto, M., Nobili, A., Mannucci, P. M.

Get full text

SIPPET: methodology, analysis and generalizability by Peyvandi, F., Mannucci, P. M., Palla, R., Rosendaal, F. R.

“…The development of anti‐FVIII neutralizing alloantibodies (inhibitors), occurring in about one‐third of previously untreated patients (PUPs) with severe…”
Get full text

Prevalence of potentially inappropriate medications and risk of adverse clinical outcome in a cohort of hospitalized elderly patients: results from the REPOSI Study by Pasina, L., Djade, C. D., Tettamanti, M., Franchi, C., Salerno, F., Corrao, S., Marengoni, A., Marcucci, M., Mannucci, P. M., Nobili, A.

“…Summary What is known and objective Inappropriate prescribing is highly prevalent for older people and has become a global healthcare concern because of its…”
Get full text

Long COVID: A patient perspective by Harari, S., Ripamonti, L., Marveggio, P., Mannucci, P.M.

Get full text

Severe hemophilia with mild bleeding phenotype: molecular characterization and global coagulation profile by SANTAGOSTINO, E., MANCUSO, M. E., TRIPODI, A., CHANTARANGKUL, V., CLERICI, M., GARAGIOLA, I., MANNUCCI, P. M.

“…Background: Patients with severe hemophilia may show very varied bleeding tendencies, and the reasons for this heterogeneous clinical expression are unclear…”
Get full text

Recombinant porcine factor VIII: a new instalment of a long story by Mannucci, P. M.

Get full text

The complex differential diagnosis between thrombotic thrombocytopenic purpura and the atypical hemolytic uremic syndrome: Laboratory weapons and their impact on treatment choice and monitoring by Mannucci, P.M, Cugno, M

“…Abstract Thrombocytopenia and microangiopathic hemolytic anemia are the hallmark of the thrombotic microangiopathies (TMAs) thrombotic thrombocytopenic purpura…”
Get full text

Sustainable and personalized nutrition: From earth health to public health by Agostoni, C., Boccia, S, Banni, S, Mannucci, P.M., Astrup, A

“…•The main dietary recommendations currently suggest to limit the intake of satured fats.•Yet, recent data fail to demonstrate harm of saturated fats for the…”
Get full text

Pharmacokinetics and safety of fibrinogen concentrate by MANCO‐JOHNSON, M. J., DIMICHELE, D., CASTAMAN, G., FREMANN, S., KNAUB, S., KALINA, U., PEYVANDI, F., PISEDDU, G., MANNUCCI, P.

“…Background: Although fibrinogen concentrate has been available for the treatment of congenital fibrinogen deficiency for years, knowledge of its…”
Get full text

Tailoring hemostatic therapies to lower inhibitor development in previously untreated patients with severe hemophilia A by Mannucci, P. M., Mancuso, M. E., Franchini, M.

“…Summary After technological progress provided safer therapeutic products for patients with hemophilia A, the development of alloantibodies (inhibitors)…”
Get full text

Effects on bleeding complications of pharmacogenetic testing for initial dosing of vitamin K antagonists: a systematic review and meta‐analysis by Franchini, M., Mengoli, C., Cruciani, M., Bonfanti, C., Mannucci, P. M.

“…Summary Background Although warfarin and other vitamin K antagonists (VKAs) are the most widely used oral anticoagulants for the prevention and treatment of…”
Get full text