Search Results - "MANNING, M"
-
1
Essay: Collections of Deformable Particles Present Exciting Challenges for Soft Matter and Biological Physics
Published in Physical review letters (31-03-2023)“…The field of soft matter physics has expanded rapidly over the past several decades, as physicists realize that a broad set of materials and systems are…”
Get full text
Journal Article -
2
Effect of cellular rearrangement time delays on the rheology of vertex models for confluent tissues
Published in PLoS computational biology (07-06-2021)“…Large-scale tissue deformation during biological processes such as morphogenesis requires cellular rearrangements. The simplest rearrangement in confluent…”
Get full text
Journal Article -
3
Rigidity in mechanical biological networks
Published in Current biology (21-10-2024)“…Multicellular organisms generate complex morphologies required for their function. Organisms control these morphologies by tuning active forces and by altering…”
Get more information
Journal Article -
4
Jamming and arrest of cell motion in biological tissues
Published in Current opinion in cell biology (01-10-2021)“…Collective cell motility is crucial to many biological processes including morphogenesis, wound healing, and cancer invasion. Recently, the biology and…”
Get full text
Journal Article -
5
A geometrically controlled rigidity transition in a model for confluent 3D tissues
Published in New journal of physics (15-02-2018)“…The origin of rigidity in disordered materials is an outstanding open problem in statistical physics. Previously, a class of 2D cellular models has been shown…”
Get full text
Journal Article -
6
A density-independent rigidity transition in biological tissues
Published in Nature physics (01-12-2015)“…Cell migration is important in many biological processes, including embryonic development, cancer metastasis and wound healing. In these tissues, a cell’s…”
Get full text
Journal Article -
7
A minimal-length approach unifies rigidity in underconstrained materials
Published in Proceedings of the National Academy of Sciences - PNAS (02-04-2019)“…We present an approach to understand geometric-incompatibility–induced rigidity in underconstrained materials, including subisostatic 2D spring networks and 2D…”
Get full text
Journal Article -
8
Aggregation and segregation of confined active particles
Published in Soft matter (14-09-2014)“…We simulate a model of self-propelled disks with soft repulsive interactions confined to a box in two dimensions. For small rotational diffusion rates,…”
Get more information
Journal Article -
9
Vibrational modes identify soft spots in a sheared disordered packing
Published in Physical review letters (02-09-2011)“…We analyze low-frequency vibrational modes in a two-dimensional, zero-temperature, quasistatically sheared model glass to identify a population of structural…”
Get full text
Journal Article -
10
Anomalous glassy dynamics in simple models of dense biological tissue
Published in Europhysics letters (01-02-2018)“…In order to understand the mechanisms for glassy dynamics in biological tissues and shed light on those in non-biological materials, we study the…”
Get full text
Journal Article -
11
Cell and Nucleus Shape as an Indicator of Tissue Fluidity in Carcinoma
Published in Physical review. X (01-02-2021)“…Tissue, cell, and nucleus morphology change during tumor progression. In 2D confluent cell cultures, different tissue states, such as fluid (unjammed) and…”
Get full text
Journal Article -
12
Energy barriers and cell migration in densely packed tissues
Published in Soft matter (28-03-2014)“…Recent observations demonstrate that confluent tissues exhibit features of glassy dynamics, such as caging behavior and dynamical heterogeneities, although it…”
Get more information
Journal Article -
13
Anisotropy links cell shapes to tissue flow during convergent extension
Published in Proceedings of the National Academy of Sciences - PNAS (16-06-2020)“…Within developing embryos, tissues flow and reorganize dramatically on timescales as short as minutes. This includes epithelial tissues, which often narrow and…”
Get full text
Journal Article -
14
Using cell deformation and motion to predict forces and collective behavior in morphogenesis
Published in Seminars in cell & developmental biology (01-07-2017)“…•The mechanical properties of biological tissues are important for their function.•Models predict constitutive laws explaining how tissues deform in response…”
Get full text
Journal Article -
15
Correlating cell shape and cellular stress in motile confluent tissues
Published in Proceedings of the National Academy of Sciences - PNAS (28-11-2017)“…Collective cell migration is a highly regulated process involved in wound healing, cancer metastasis, and morphogenesis. Mechanical interactions among cells…”
Get full text
Journal Article -
16
Knowing the Boundaries: Extending the Differential Adhesion Hypothesis in Embryonic Cell Sorting
Published in Science (American Association for the Advancement of Science) (12-10-2012)“…Successful embryogenesis requires proper sorting and compartmentalization of different cell types. Mechanical interactions between cells help govern these…”
Get full text
Journal Article -
17
Unjamming and cell shape in the asthmatic airway epithelium
Published in Nature materials (01-10-2015)“…From coffee beans flowing in a chute to cells remodelling in a living tissue, a wide variety of close-packed collective systems—both inert and living—have the…”
Get full text
Journal Article -
18
C−H Functionalization of Commodity Polymers
Published in Angewandte Chemie International Edition (24-06-2019)“…Synthetic manipulation of polymer substrates is one of the oldest and most reliable methods to increase the functional diversity of soft materials. Modifying…”
Get full text
Journal Article -
19
Simple and Broadly Applicable Definition of Shear Transformation Zones
Published in Physical review letters (08-01-2021)“…Plastic deformation in amorphous solids is known to be carried by stress-induced localized rearrangements of a few tens of particles, accompanied by the…”
Get full text
Journal Article -
20
Flocking transitions in confluent tissues
Published in Soft matter (2018)“…Collective cell migration in dense tissues underlies important biological processes, such as embryonic development, wound healing and cancer invasion. While…”
Get more information
Journal Article