Search Results - "MANKERTZ, J."

Changes in expression and distribution of claudin 2, 5 and 8 lead to discontinuous tight junctions and barrier dysfunction in active Crohn’s disease by Zeissig, S, Bürgel, N, Günzel, D, Richter, J, Mankertz, J, Wahnschaffe, U, Kroesen, A J, Zeitz, M, Fromm, M, Schulzke, J-D

“…Background: Epithelial barrier function is impaired in Crohn’s disease. Aim: To define the underlying cellular mechanisms with special attention to tight…”
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Antibiotika‐Rückstände in Fleisch: Vergleich von Drei‐ und Fünf‐Platten‐Hemmstofftests für Screening‐Analysen by Borzekowski, A., Jähne, M., Uhlig, S., Mankertz, J., Gowik, P.

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Interleukin-13 is the key effector Th2 cytokine in ulcerative colitis that affects epithelial tight junctions, apoptosis, and cell restitution by Heller, Frank, Florian, Peter, Bojarski, Christian, Richter, Jan, Christ, Melanie, Hillenbrand, Bernd, Mankertz, Joachim, Gitter, Alfred H, Bürgel, Nataly, Fromm, Michael, Zeitz, Martin, Fuss, Ivan, Strober, Warren, Schulzke, Jörg D

“…Ulcerative colitis (UC) is characterized by a Th2 immune response with inflammation and epithelial barrier dysfunction. So far, Th2 cytokines have not been…”
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Epithelial transport and barrier function in occludin-deficient mice by Schulzke, J.D., Gitter, A.H., Mankertz, J., Spiegel, S., Seidler, U., Amasheh, S., Saitou, M., Tsukita, S., Fromm, M.

“…This study aimed at functional characterization of the tight junction protein occludin using the occludin-deficient mouse model. Epithelial transport and…”
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Laborübergreifende Validierungsstudie: Anwendung eines faktoriellen Designs als alternativen Validierungsansatz für die Bestätigungsmethode Beta‐Agonisten in Leber (unter Berücksichtigung der neuen MMPR) by Borzekowski, A., Mankertz, J., Polzer, J.

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Downregulation of epithelial apoptosis and barrier repair in active Crohn’s disease by tumour necrosis factor α antibody treatment by Zeissig, S, Bojarski, C, Buergel, N, Mankertz, J, Zeitz, M, Fromm, M, Schulzke, J D

“…Background and aims: Barrier dysfunction is an important feature contributing to inflammation and diarrhoea in Crohn’s disease (CD). Recently, tumour necrosis…”
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TNFα up-regulates claudin-2 expression in epithelial HT-29/B6 cells via phosphatidylinositol-3-kinase signaling by Mankertz, J, Amasheh, M, Krug, S. M, Fromm, A, Amasheh, S, Hillenbrand, B, Tavalali, S, Fromm, M, Schulzke, J. D

“…Our aim has been to characterize the molecular mechanisms regulating the expression of the channel-forming tight-junctional protein claudin-2 in response to…”
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Epithelial apoptosis is a prominent feature of the epithelial barrier disturbance in intestinal inflammation: effect of pro-inflammatory interleukin-13 on epithelial cell function by Heller, F, Fromm, A, Gitter, A H, Mankertz, J, Schulzke, J-D

“…In ulcerative colitis, the T helper type 2 proinflammatory cytokine Interleukin-13 (IL-13) contributes as effector cytokine to the epithelial changes…”
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Validierung einer LC‐MS/MS Multimethode zur Analyse von Steroiden, Stilbenen und Resorcylsäurelactonen in Muskel by Rausch, A.‐K., Borzekowski, A., Grunow, M., Mönch, S., Mankertz, J.

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Expression from the human occludin promoter is affected by tumor necrosis factor alpha and interferon gamma by Mankertz, J, Tavalali, S, Schmitz, H, Mankertz, A, Riecken, E O, Fromm, M, Schulzke, J D

“…The 65 kDa protein occludin is a membrane-spanning part of the epithelial tight junction, which is the main barrier of the paracellular pathway. The function…”
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Mechanisms of diarrhea in the interleukin-2-deficient mouse model of colonic inflammation by Barmeyer, C, Harren, M, Schmitz, H, Heinzel-Pleines, U, Mankertz, J, Seidler, U, Horak, I, Wiedenmann, B, Fromm, M, Schulzke, J D

“…Colitis in interleukin-2-deficient (IL-2(-/-)) mice resembles ulcerative colitis in humans. We studied epithelial transport and barrier function in IL-2(-/-)…”
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Permeability of human HT-29/B6 colonic epithelium as a function of apoptosis by Bojarski, C., Gitter, A. H., Bendfeldt, K., Mankertz, J., Schmitz, H., Wagner, S., Fromm, M., Schulzke, J. D.

“…The barrier function of colonic epithelia is challenged by apoptotic loss of enterocytes. In monolayers of human colonic HT-29/B6 cells, apoptosis induced by…”
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Identification of a protein essential for replication of porcine circovirus by Mankertz, A, Mankertz, J, Wolf, K, Buhk, H.J

“…The largest open reading frame of porcine circovirus (ORF4) encodes a protein of 312 amino acids. The predicted gene product of ORF 4 shows similarities to Rep…”
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Mapping and characterization of the origin of DNA replication of porcine circovirus by Mankertz, A. (Robert Koch-Institut, Berlin, Germany.), Persson, F, Mankertz, J, Blaess, G, Buhk, H.J

“…The origin of DNA replication of porcine circovirus (PCV) was mapped to a 111-bp fragment. On top of a hairpin, a nonanucleotide (TAGTATTAC) homologous to…”
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Aeromonas hydrophila Beta-Hemolysin Induces Active Chloride Secretion in Colon Epithelial Cells (HT-29/B6) by EPPLE, H. J, MANKERTZ, J, IGNATIUS, R, LIESENFELD, O, FROMM, M, ZEITZ, M, CHAKRABORTY, T, SCHULZKE, J. D

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Early aldosterone effect in distal colon by transcriptional regulation of ENaC subunits by Epple, H J, Amasheh, S, Mankertz, J, Goltz, M, Schulzke, J D, Fromm, M

“…Aldosterone-induced sodium absorption is mediated by the epithelial Na(+) channel (ENaC). It is thought that the "early effect" is not based on genomic…”
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Differential Regulation of ENaC by Aldosterone in Rat Early and Late Distal Colon by AMASHEH, S., EPPLE, H. J., MANKERTZ, J., DETJEN, K., GOLTZ, M., SCHULZKE, J. D., FROMM, M.

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Tight junction proteins: a novel class of integral membrane proteins expression in human epidermis and in HaCaT keratinocytes by TEBBE, B, MANKERTZ, J, SCHWARZ, C, AMASHEH, S, FROMM, M, ASSAF, C, SCHULTZ-EHRENBURG, U, SANCHEZ RUDERISCH, H, SCHULZKE, J.-D, ORFANOS, C. E

“…Tight junction proteins comprise a novel group of integral membrane proteins necessary for cell-to-cell contacts and responsible for the barrier function in…”
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cis-acting elements in the lytic origin of DNA replication of Epstein-Barr virus by Schepers, A, Pich, D, Mankertz, J, Hammerschmidt, W

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Diversity of antimicrobial resistance pheno- and genotypes of methicillin-resistant Staphylococcus aureus ST398 from diseased swine by Kadlec, Kristina, Ehricht, Ralf, Monecke, Stefan, Steinacker, Ulrike, Kaspar, Heike, Mankertz, Joachim, Schwarz, Stefan

“…Objectives Fifty-four methicillin-resistant Staphylococcus aureus (MRSA) ST398 isolates from unrelated diseased swine collected all over Germany were…”
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