Search Results - "MANDI, Yvette"
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The kynurenine system and immunoregulation
Published in Journal of Neural Transmission (01-02-2012)“…There is developing interest in the role of the kynurenines in the immune function. A considerable amount of evidence has accumulated as concerns interactions…”
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Induction of human defensins by intestinal Caco-2 cells after interactions with opportunistic Candida species
Published in Microbes and infection (01-01-2014)“…In this study we investigated the effects of Candida albicans, Candida krusei, Candida tropicalis and Candida parapsilosis on human beta-defensin 2 (HBD-2)…”
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Identification and Characterization of a Novel, Psoriasis Susceptibility-related Noncoding RNA gene, PRINS
Published in The Journal of biological chemistry (24-06-2005)“…To identify genetic factors contributing to psoriasis susceptibility, gene expression profiles of uninvolved epidermis from psoriatic patients and epidermis…”
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Analysis of plasma levels and polymorphisms of S100A8/9 and S100A12 in patients with acute pancreatitis
Published in Pancreas (01-04-2014)Get full text
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Immune Influencers in Action: Metabolites and Enzymes of the Tryptophan-Kynurenine Metabolic Pathway
Published in Biomedicines (25-06-2021)“…The tryptophan (TRP)-kynurenine (KYN) metabolic pathway is a main player of TRP metabolism through which more than 95% of TRP is catabolized. The pathway is…”
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Importance of cytokines, nitric oxide, and apoptosis in the pathological process of necrotizing pancreatitis in rats
Published in Pancreas (01-08-2004)“…Ischemia-reperfusion injury can be involved in the pathophysiology of acute necrotizing pancreatitis. The aim of our study was to determine the production of…”
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Potential role of human -defensin 1 in Helicobacter pylori-induced gastritis
Published in Scandinavian journal of gastroenterology (2009)“…Objective. Helicobacter pylori-induced gastric inflammation is dependent on the persistence of the microorganism in the gastric epithelium. Modulation of the…”
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GENETIC POLYMORPHISMS OF HUMAN β-DEFENSINS IN PATIENTS WITH MULTIPLE SCLEROSIS
Published in Ideggyógyászati szemle (30-03-2015)“…Recent studies have started to elucidate the contribution of microbiome to the pathogenesis of multiple sclerosis (MS). It is also supposed, that…”
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Editorial: Multiple Implications of the Kynurenine Pathway in Inflammatory Diseases: Diagnostic and Therapeutic Applications
Published in Frontiers in immunology (11-02-2022)Get full text
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Kynurenic Acid Analog Attenuates the Production of Tumor Necrosis Factor-α, Calgranulins (S100A 8/9 and S100A 12), and the Secretion of HNP1-3 and Stimulates the Production of Tumor Necrosis Factor-Stimulated Gene-6 in Whole Blood Cultures of Patients With Rheumatoid Arthritis
Published in Frontiers in immunology (09-04-2021)“…Rheumatoid arthritis (RA) is a chronic, inflammatory joint disease with complex pathogenesis involving a variety of immunological events. Recently, it has been…”
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The Opposite Effects of Kynurenic Acid and Different Kynurenic Acid Analogs on Tumor Necrosis Factor-α (TNF-α) Production and Tumor Necrosis Factor-Stimulated Gene-6 (TSG-6) Expression
Published in Frontiers in immunology (21-06-2019)“…The investigation of anti-inflammatory and immunosuppressive functions of Kynurenic acid (KYNA) is now in focus. There is also substantial evidence that TSG-6…”
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The Risk of Early and Late Lung Sequelae After Conformal Radiotherapy in Breast Cancer Patients
Published in International journal of radiation oncology, biology, physics (01-07-2007)“…Purpose: To study the risks of early and late radiogenic lung damage in breast cancer patients after conformal radiotherapy. Methods and Materials: Radiogenic…”
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Relevance of α-defensins(HNP1-3) and defensin β-1 in diabetes
Published in World journal of gastroenterology : WJG (21-07-2014)“…AIM: To investigate the genetic background of human defensin expression in type 1 and 2 diabetes.METHODS: Associations between DEFA1/DEFA3 gene copy number…”
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Evaluation of the Genetic Variants of Kinesin Motor Protein in Ischemic Stroke
Published in Journal of stroke and cerebrovascular diseases (01-09-2009)“…Background The kinesin light-chain 1 genetic variants G56836C, A185C, and C406T were earlier found to amplify the development of leukoaraiosis in hypertensive…”
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Different inhibitory effects of kynurenic acid and a novel kynurenic acid analogue on tumour necrosis factor-α (TNF-α) production by mononuclear cells, HMGB1 production by monocytes and HNP1-3 secretion by neutrophils
Published in Naunyn-Schmiedeberg's archives of pharmacology (01-05-2011)“…Kynurenic acid (KynA), a broad spectrum antagonist of excitatory amino acid receptors, may serve as a protective agent in neurological disorders. The potential…”
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Vesicular stomatitis virus induces apoptosis in the Wong-Kilbourne derivative of the Chang conjunctival cell line
Published in Graefe's archive for clinical and experimental ophthalmology (01-06-2006)“…Virotherapy represents a novel therapeutic modality for the treatment of malignant diseases. Vesicular stomatitis virus (VSV) has been shown to exert antitumor…”
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Inhibitory action of a new proton pump inhibitor, trifluoromethyl ketone derivative, against the motility of clarithromycin-susceptible and-resistant Helicobacter pylori
Published in International journal of antimicrobial agents (01-06-2004)“…We previously reported that a trifluoromethyl ketone derivative, 1-(2-benzoxazolyl)-3,3,3-trifluoro-2-propanone ( TF18), exhibited the potent antibacterial…”
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The effects of hypo- and hyperthermic pretreatment on sodium taurocholate-induced acute pancreatitis in rats
Published in Pancreas (2002)“…Heat shock proteins (HSPs) have indispensable functions in the synthesis, degradation, folding, transport, and translocation of intracellular proteins. HSPs…”
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Intraperitoneally administered IgG from patients with amyotrophic lateral sclerosis or from an immune-mediated goat model increase the levels of TNF-α, IL-6, and IL-10 in the spinal cord and serum of mice
Published in Journal of neuroinflammation (24-05-2016)“…Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease that involves the selective loss of the upper and lower motor neurons (MNs)…”
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Relevance of defensin β-2 and α defensins (HNP1-3) in Alzheimer's disease
Published in Psychiatry research (30-05-2016)“…Abstract The DEFB4 gene copy numbers were investigated in 206 AD patients and in 250 controls. The levels of the human defensin β−2 (hBD2) and α-defensins (HNP…”
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