Search Results - "MANDELLI, F"

PML–RARα kinetics and impact of FLT3–ITD mutations in newly diagnosed acute promyelocytic leukaemia treated with ATRA and ATO or ATRA and chemotherapy by Cicconi, L, Divona, M, Ciardi, C, Ottone, T, Ferrantini, A, Lavorgna, S, Alfonso, V, Paoloni, F, Piciocchi, A, Avvisati, G, Ferrara, F, Di Bona, E, Albano, F, Breccia, M, Cerqui, E, Sborgia, M, Kropp, M G, Santoro, A, Levis, A, Sica, S, Amadori, S, Voso, M T, Mandelli, F, Lo-Coco, F

“…The APL0406 study showed that arsenic trioxide (ATO) and all -trans retinoic acid (ATRA) are not inferior to standard ATRA and chemotherapy (CHT) in newly…”
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Investigating factors associated with adherence behaviour in patients with chronic myeloid leukemia: an observational patient-centered outcome study by Efficace, F, Baccarani, M, Rosti, G, Cottone, F, Castagnetti, F, Breccia, M, Alimena, G, Iurlo, A, Rossi, A R, Pardini, S, Gherlinzoni, F, Salvucci, M, Tiribelli, M, Vignetti, M, Mandelli, F

“…Background: Optimal adherence to imatinib therapy is of paramount importance to maximise treatment effectiveness in patients with chronic myeloid leukaemia…”
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Chronic fatigue is the most important factor limiting health-related quality of life of chronic myeloid leukemia patients treated with imatinib by Efficace, F, Baccarani, M, Breccia, M, Cottone, F, Alimena, G, Deliliers, G L, Baratè, C, Specchia, G, Di Lorenzo, R, Luciano, L, Turri, D, Martino, B, Stagno, F, Dabusti, M, Bergamaschi, M, Leoni, P, Simula, M P, Levato, L, Fava, C, Veneri, D, Sica, S, Rambaldi, A, Rosti, G, Vignetti, M, Mandelli, F

“…Health-related quality of life (HRQOL) is an important goal of therapy for chronic myeloid leukemia (CML) patients treated with current molecular-targeted…”
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Assessment of balance impairment in patients with symptomatic cervical spinal stenosis with and without myelopathy by Mandelli, F., Nüesch, C., Mündermann, A., Schären, S., Urbanschitz, L., Netzer, C.

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Thermal adaptation strategies of the extremophile bacterium Thermus filiformis based on multi-omics analysis by Mandelli, F., Couger, M. B., Paixão, D. A. A., Machado, C. B., Carnielli, C. M., Aricetti, J. A., Polikarpov, I., Prade, R., Caldana, C., Paes Leme, A. F., Mercadante, A. Z., Riaño-Pachón, D. M., Squina, Fabio Marcio

“…Thermus filiformis is an aerobic thermophilic bacterium isolated from a hot spring in New Zealand. The experimental study of the mechanisms of thermal…”
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Simultaneous production of xylooligosaccharides and antioxidant compounds from sugarcane bagasse via enzymatic hydrolysis by Mandelli, F., Brenelli, L.B., Almeida, R.F., Goldbeck, R., Wolf, L.D., Hoffmam, Z.B., Ruller, R., Rocha, G.J.M., Mercadante, A.Z., Squina, F.M.

“…•Simultaneous production of value-added products from sugarcane bagasse through chimeric enzyme.•Pre-treatment of sugarcane bagasse improves the enzymatic…”
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Preference for involvement in treatment decisions and request for prognostic information in newly diagnosed patients with higher-risk myelodysplastic syndromes by Efficace, F., Gaidano, G., Sprangers, M., Cottone, F., Breccia, M., Voso, M.T., Caocci, G., Stauder, R., Di Tucci, A.A., Sanpaolo, G., Selleslag, D., Angelucci, E., Platzbecker, U., Mandelli, F.

“…The main objective of this study was to assess preferences for involvement in treatment decisions and requests for prognostic information in newly diagnosed…”
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Imatinib mesylate may improve fasting blood glucose in diabetic Ph+ chronic myelogenous leukemia patients responsive to treatment by Breccia, M, Muscaritoli, M, Aversa, Z, Mandelli, F, Alimena, G

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Translocations and mutations involving the nucleophosmin (NPM1) gene in lymphomas and leukemias by Falini, Brunangelo, Nicoletti, Ildo, Bolli, Niccolo, Martelli, Maria Paola, Liso, Arcangelo, Gorello, Paolo, Mandelli, Franco, Mecucci, Cristina, Martelli, Massimo Fabrizio

“…From the Section of Hematology and Immunology, University of Perugia, IBit Foundation, Perugia, Italy (BF, NB, PG, CM, MFM); Institute of Internal Medicine,…”
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Extramedullary Involvement at Relapse in Acute Promyelocytic Leukemia Patients Treated or Not With All-Trans Retinoic Acid: A Report by the Gruppo Italiano Malattie Ematologiche dell’Adulto by SPECCHIA, Giorgina, LO COCO, Francesco, LISO, Vincenzo, MANDELLI, Franco, VIGNETTI, Marco, AWISATI, Giuseppe, FAZI, Paola, ALBANO, Francesco, DI RAIMONDO, Francesco, MARTINO, Bruno, FERRARA, Felicetto, SELLERI, Carmine

“…Recent reports of extramedullary disease (EMD) at recurrence in acute promyelocytic leukemia (APL) have raised increasing concern about a possible role of…”
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Occurrence of thrombotic events in acute promyelocytic leukemia correlates with consistent immunophenotypic and molecular features by BRECCIA, M, AVVISATI, G, LO-COCO, F, LATAGLIATA, R, CARMOSINO, I, GUARINI, A, DE PROPRIS, M. S, GENTILINI, F, PETTI, M. C, CIMINO, G, MANDELLI, F

“…Although the occurrence of thrombosis in acute promyelocytic leukemia (APL) has been reported during retinoic acid treatment, no studies carried out in large…”
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The impact of comorbidity on health-related quality of life in elderly patients with chronic myeloid leukemia by Efficace, F., Rosti, G., Breccia, M., Cottone, F., Giesinger, J. M., Stagno, F., Iurlo, A., Russo Rossi, A., Luciano, L., Martino, B., Galimberti, S., Turri, D., Bergamaschi, M., Tiribelli, M., Fava, C., Angelucci, E., Mandelli, F., Baccarani, M.

“…The primary objective of this study was to investigate whether the presence of comorbidities was associated with a lower health-related quality of life (HRQOL)…”
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High numbers of mobilized CD34+ cells collected in AML in first remission are associated with high relapse risk irrespective of treatment with autologous peripheral blood SCT or autologous BMT by Hengeveld, M, Suciu, S, Chelgoum, Y, Marie, J-P, Muus, P, Lefrère, F, Mandelli, F, Pane, F, Amadori, S, Fioritoni, G, Labar, B, Baron, F, Cermak, J, Bourhis, J-H, Storti, G, Fazi, P, Hagemeijer, A, Vignetti, M, Willemze, R, de Witte, T

“…The faster hematopoietic recovery after autologous peripheral blood SCT (APBSCT) in patients with AML may be offset by an increased relapse risk as compared…”
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Accuracy of physician assessment of treatment preferences and health status in elderly patients with higher-risk myelodysplastic syndromes by Caocci, G, Voso, M.T, Angelucci, E, Stauder, R, Cottone, F, Abel, G, Nguyen, K, Platzbecker, U, Beyne-Rauzy, O, Gaidano, G, Invernizzi, R, Molica, S, Criscuolo, M, Breccia, M, Lübbert, M, Sanpaolo, G, Buccisano, F, Ricco, A, Palumbo, G.A, Niscola, P, Zhang, H, Fenu, S, La Nasa, G, Mandelli, F, Efficace, F

“…Highlights • It is essential for physicians to focus attention on patient needs and preferences. • Physicians’ perceptions are frequently inconsistent with MDS…”
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Characterization and Low-Resolution Structure of an Extremely Thermostable Esterase of Potential Biotechnological Interest from Pyrococcus furiosus by Mandelli, F., Gonçalves, T. A., Gandin, C. A., Oliveira, A. C. P., Oliveira Neto, M., Squina, F. M.

“…Enzymes isolated from extremophiles often exhibit superior performance and potential industrial applications. There are several advantages performing…”
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Time for a new era in the evaluation of targeted therapies for patients with chronic myeloid leukemia: Inclusion of quality of life and other patient-reported outcomes by Efficace, F, Cocks, K, Breccia, M, Sprangers, M, Meyers, C.A, Vignetti, M, Baccarani, M, Mandelli, F

“…Abstract Health-related quality of life (HRQOL) and other patient-reported outcomes (PROs) might be crucial in comparing effectiveness of treatments as they…”
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The characterization of a thermostable and cambialistic superoxide dismutase from Thermus filiformis by Mandelli, F., Franco Cairo, J.P.L., Citadini, A.P.S., Büchli, F., Alvarez, T.M., Oliveira, R.J., Leite, V.B.P., Paes Leme, A.F., Mercadante, A.Z., Squina, F.M.

“…The superoxide dismutase (TfSOD) gene from the extremely thermophilic bacterium Thermus filiformis was cloned and expressed at high levels in mesophilic host…”
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Alterations of the FLT3 gene in acute promyelocytic leukemia: association with diagnostic characteristics and analysis of clinical outcome in patients treated with the italian AIDA protocol by NOGUERA, N. I, BRECCIA, M, LO COCO, F, DIVONA, M, DIVERIO, D, COSTA, V, DE SANTIS, S, AVVISATI, G, PINAZZI, M. B, PETTI, M. C, MANDELLI, F

“…Alterations in the FLT3 gene, including internal tandem duplications (ITDs) and D835 mutations occur frequently in acute myelogenous leukemia. We investigated…”
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Gemtuzumab ozogamicin (Mylotarg ) as single-agent treatment for frail patients 61 years of age and older with acute myeloid leukemia: final results of AML-15B, a phase 2 study of the European Organisation for Research and Treatment of Cancer and Gruppo Italiano Malattie Ematologiche dell'Adulto Leukemia Groups by AMADORI, S, SUCIU, S, PRUIJT, J, NOBILE, F, CASSIBBA, V, MARIE, J.-P, BEELDENS, F, BAILA, L, VIGNETTI, M, DE WITTE, T, STASI, R, WILLEMZE, R, MANDELLI, F, SELLESLAG, D, DENZLINGER, C, MUUS, P, STAUDER, R, BERNEMAN, Z

“…The therapeutic activity and toxicity profile of gemtuzumab ozogamicin were assessed in 40 patients >60 years of age with acute myeloid leukemia (AML) who were…”
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Idiopathic thrombocytopenic purpura (ITP) in the elderly: clinical course in 178 patients by Bizzoni, L., Mazzucconi, M. G., Gentile, M., Santoro, C., Bernasconi, S., Chiarotti, F., Foà, R., Mandelli, F.

“…:  Idiopathic thrombocytopenic purpura (ITP) is often diagnosed in the elderly (age ≥65 yr), where it generally presents as a chronic disease. The objective of…”
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