Search Results - "MANDELKERN, M. A"
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Midbrain functional connectivity and ventral striatal dopamine D2-type receptors: link to impulsivity in methamphetamine users
Published in Molecular psychiatry (01-11-2016)“…Stimulant use disorders are associated with deficits in striatal dopamine receptor availability, abnormalities in mesocorticolimbic resting-state functional…”
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Rapid effects of brief intensive cognitive-behavioral therapy on brain glucose metabolism in obsessive-compulsive disorder
Published in Molecular psychiatry (01-02-2009)“…Brief intensive cognitive-behavioral therapy (CBT) using exposure and response prevention significantly improves obsessive-compulsive disorder (OCD) symptoms…”
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Supraphysiological doses of levothyroxine alter regional cerebral metabolism and improve mood in bipolar depression
Published in Molecular psychiatry (01-05-2005)“…Supplementation of standard treatment with high-dose levothyroxine (L-T(4)) is a novel approach for treatment-refractory bipolar disorders. This study tested…”
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Regional cerebral activity in normal and pathological perception of visceral pain
Published in Gastroenterology (New York, N.Y. 1943) (1997)“…BACKGROUND & AIMS: To characterize the cerebral processing of noxious visceral events, changes in regional cerebral blood flow associated with perception of…”
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Changes in cerebral glucose metabolism during early abstinence from chronic methamphetamine abuse
Published in Molecular psychiatry (01-09-2008)“…Changes in brain function during the initial weeks of abstinence from chronic methamphetamine abuse may substantially affect clinical outcome, but are not well…”
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Neural and psychological predictors of treatment response in irritable bowel syndrome patients with a 5‐HT3 receptor antagonist: a pilot study
Published in Alimentary pharmacology & therapeutics (01-08-2008)“…Aliment Pharmacol Ther 28, 344–352 Summary Background Symptom improvement in irritable bowel syndrome (IBS) treatment trials varies widely, with only 50–70%…”
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Striatal dopamine D1-type receptor availability: no difference from control but association with cortical thickness in methamphetamine users
Published in Molecular psychiatry (01-05-2018)“…Chronic methamphetamine use poses potentially devastating consequences for directly affected individuals and for society. Lower dopamine D2-type receptor…”
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Gray-matter volume, midbrain dopamine D2/D3 receptors and drug craving in methamphetamine users
Published in Molecular psychiatry (01-06-2015)“…Dysfunction of the mesocorticolimbic system has a critical role in clinical features of addiction. Despite evidence suggesting that midbrain dopamine receptors…”
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The relationship between psychiatric symptoms and regional cortical metabolism in Alzheimer's disease
Published in The journal of neuropsychiatry and clinical neurosciences (01-11-1995)“…Cognitive and noncognitive psychiatric symptoms were systematically evaluated in 21 patients with Alzheimer's disease by using the Neurobehavioral Rating…”
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Predictors of cognitive change in middle-aged and older adults with memory loss
Published in The American journal of psychiatry (01-12-1995)“…Previous longitudinal studies of age-related memory loss have focused on objective neuropsychological measures that predict subsequent cognitive change, yet…”
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Low striatal dopamine receptor availability linked to caloric intake during abstinence from chronic methamphetamine abuse
Published in Molecular psychiatry (01-06-2012)Get full text
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The Effects of an Alpha-2 Adrenergic Agonist, Guanfacine, on rCBF in Human Cortex in Normal Controls and Subjects with Focal Epilepsy
Published in Neuropsychopharmacology (New York, N.Y.) (01-09-2000)“…Alpha-2 noradrenergic agonists may have wide applicability in the treatment of pre-frontal cortex deficits in primates and behavioral dysfunction in man. We…”
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Brain metabolic changes associated with symptom factor improvement in major depressive disorder
Published in Biological psychiatry (1969) (01-08-2001)“…Background: Symptoms of major depressive disorder (MDD) have been linked to regional brain function through imaging studies of symptom provocation in normal…”
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Differences in brain responses to visceral pain between patients with irritable bowel syndrome and ulcerative colitis
Published in Pain (Amsterdam) (01-06-2005)“…Patients with mild chronic inflammation of the rectum or ileum have reduced perceptual responses to rectosigmoid distension compared to patients with irritable…”
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Cerebral metabolic dysfunction in AIDS: findings in a sample with and without dementia
Published in The journal of neuropsychiatry and clinical neurosciences (1992)“…Positron-emission tomography was coupled with neurological and neuropsychological evaluation to study regional cerebral activity and neurologic status in two…”
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Reliability of drawing regions of interest for positron emission tomographic data
Published in Psychiatry research (01-11-1992)“…We determined interrater reliability for two raters who independently used a standard protocol to draw regions of interest (ROIs) on F-18 fluorodeoxyglucose…”
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Proton electromagnetic form factors in the timelike region from 8.9 to 13.0 GeV2
Published in Physical review letters (01-03-1993)Get full text
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Risk-taking behavior: dopamine D2/D3 receptors, feedback, and frontolimbic activity
Published in Cerebral cortex (New York, N.Y. 1991) (01-01-2015)“…Decision-making involves frontolimbic and dopaminergic brain regions, but how prior choice outcomes, dopamine neurotransmission, and frontostriatal activity…”
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Dynamic [18F]fluorodeoxyglucose positron emission tomography and hypometabolic zones in seizures: reduced capillary influx
Published in Annals of neurology (01-06-1998)“…We performed dynamic [18F]fluorodeoxyglucose ([18F]FDG) positron emission tomographic (PET) analyses in 8 patients. Rate constants of influx (K1*), efflux…”
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