Search Results - "MAMDANI, M."

Fixed-dose combination antihypertensive medications, adherence, and clinical outcomes: A population-based retrospective cohort study by Verma, Amol A, Khuu, Wayne, Tadrous, Mina, Gomes, Tara, Mamdani, Muhammad M

“…The majority of people with hypertension require more than one medication to achieve blood pressure control. Many patients are prescribed multipill…”
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Gabapentin, opioids, and the risk of opioid-related death: A population-based nested case-control study by Gomes, Tara, Juurlink, David N, Antoniou, Tony, Mamdani, Muhammad M, Paterson, J Michael, van den Brink, Wim

“…Prescription opioid use is highly associated with risk of opioid-related death, with 1 of every 550 chronic opioid users dying within approximately 2.5 years…”
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Prescribing of opioid analgesics and related mortality before and after the introduction of long-acting oxycodone by Dhalla, Irfan A, Mamdani, Muhammad M, Sivilotti, Marco L A, Kopp, Alex, Qureshi, Omar, Juurlink, David N

“…Opioid-related mortality appears to be increasing in Canada. We examined the true extent of the problem and the impact of the introduction of long-acting…”
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A population-based study of the drug interaction between proton pump inhibitors and clopidogrel by Juurlink, David N, Gomes, Tara, Ko, Dennis T, Szmitko, Paul E, Austin, Peter C, Tu, Jack V, Henry, David A, Kopp, Alex, Mamdani, Muhammad M

“…Most proton pump inhibitors inhibit the bioactivation of clopidogrel to its active metabolite. The clinical significance of this drug interaction is unknown…”
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A comparison of propensity score methods: a case-study estimating the effectiveness of post-AMI statin use by Austin, Peter C., Mamdani, Muhammad M.

“…There is an increasing interest in the use of propensity score methods to estimate causal effects in observational studies. However, recent systematic reviews…”
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Pregabalin and the Risk for Opioid-Related Death: A Nested Case-Control Study by Gomes, Tara, Greaves, Simon, van den Brink, Wim, Antoniou, Tony, Mamdani, Muhammad M, Paterson, J Michael, Martins, Diana, Juurlink, David N

“…Gomes et al. discussed a case-control study of the relationship between pregabalin and the risk for opioid-related death. They examined the risk for…”
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Contributions of prescribed and non-prescribed opioids to opioid related deaths: population based cohort study in Ontario, Canada by Gomes, Tara, Khuu, Wayne, Martins, Diana, Tadrous, Mina, Mamdani, Muhammad M, Paterson, J Michael, Juurlink, David N

“…AbstractObjectiveTo describe the contributions of prescribed and non-prescribed opioids to opioid related deaths.DesignPopulation based cohort…”
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Sex Differences in Dose Escalation and Overdose Death during Chronic Opioid Therapy: A Population-Based Cohort Study by Kaplovitch, Eric, Gomes, Tara, Camacho, Ximena, Dhalla, Irfan A, Mamdani, Muhammad M, Juurlink, David N

“…The use of opioids for noncancer pain is widespread, and more than 16,000 die of opioid-related causes in the United States annually. The patients at greatest…”
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Proton Pump Inhibitors and Hospitalization for Clostridium Difficile—Associated Disease: A Population-Based Study by Lowe, Donna O., Mamdani, Muhammad M., Kopp, Alexander, Low, Donald E., Juurlink, David N.

“…Background. Previous studies have examined the association between proton pump inhibitor (PPI) use and the risk of Clostridium difficile-associated disease…”
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The risk of falls on initiation of antihypertensive drugs in the elderly by Butt, D. A., Mamdani, M., Austin, P. C., Tu, K., Gomes, T., Glazier, R. H.

“…Summary Antihypertensive drugs are associated with an immediate increased falls risk in elderly patients which was significant during the first 14 days after…”
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Rates of hemorrhage during warfarin therapy for atrial fibrillation by Gomes, Tara, Mamdani, Muhammad M, Holbrook, Anne M, Paterson, J Michael, Hellings, Chelsea, Juurlink, David N

“…Although warfarin has been extensively studied in clinical trials, little is known about rates of hemorrhage attributable to its use in routine clinical…”
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Risk of Suicide Following Deliberate Self-poisoning by Finkelstein, Yaron, Macdonald, Erin M, Hollands, Simon, Sivilotti, Marco L A, Hutson, Janine R, Mamdani, Muhammad M, Koren, Gideon, Juurlink, David N

“…Suicide is the tenth leading cause of death in the United States, and its rate has risen by 16% in the past decade. Deliberate self-poisoning is the leading…”
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Clinical indications associated with opioid initiation for pain management in Ontario, Canada: a population-based cohort study by Pasricha, Sachin V., Tadrous, Mina, Khuu, Wayne, Juurlink, David N., Mamdani, Muhammad M., Paterson, J. Michael, Gomes, Tara

“…Concerns over prescription opioids contributing to high levels of opioid use disorder and overdose have led policymakers and clinicians to seek means to reduce…”
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Co-trimoxazole and sudden death in patients receiving inhibitors of renin-angiotensin system: population based study by Fralick, Michael, Macdonald, Erin M, Gomes, Tara, Antoniou, Tony, Hollands, Simon, Mamdani, Muhammad M, Juurlink, David N

“…Objective To determine whether the prescription of co-trimoxazole with an angiotensin converting enzyme inhibitor or angiotensin receptor blocker is associated…”
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The Influence of Socioeconomic Status on Selection of Anticoagulation for Atrial Fibrillation by Sholzberg, Michelle, Gomes, Tara, Juurlink, David N, Yao, Zhan, Mamdani, Muhammad M, Laupacis, Andreas

“…Without third-party insurance, access to marketed drugs is limited to those who can afford to pay. We examined this phenomenon in the context of…”
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Outpatient Gatifloxacin Therapy and Dysglycemia in Older Adults by Park-Wyllie, Laura Y, Juurlink, David N, Kopp, Alexander, Shah, Baiju R, Stukel, Therese A, Stumpo, Carmine, Dresser, Linda, Low, Donald E, Mamdani, Muhammad M

“…Gatifloxacin has been associated with both hypoglycemia and hyperglycemia. This study examined dysglycemia-related health outcomes associated with the use of…”
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The risk of hypotension following co-prescription of macrolide antibiotics and calcium-channel blockers by Wright, Alissa J, Gomes, Tara, Mamdani, Muhammad M, Horn, John R, Juurlink, David N

“…The macrolide antibiotics clarithromycin and erythromycin may potentiate calcium-channel blockers by inhibiting cytochrome P450 isoenzyme 3A4. However, this…”
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Changing patterns of opioid initiation for pain management in Ontario, Canada: A population-based cross-sectional study by Gomes, Tara, Men, Siyu, Campbell, Tonya J, Tadrous, Mina, Mamdani, Muhammad M, Paterson, J Michael, Juurlink, David N

“…The recent publication of a national guideline and quality standards in Canada have provided clinicians with new, evidence-based recommendations on safe,…”
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Risk of incident diabetes among patients treated with statins: population based study by Carter, Aleesa A, Gomes, Tara, Camacho, Ximena, Juurlink, David N, Shah, Baiju R, Mamdani, Muhammad M

“…Objective To examine the risk of new onset diabetes among patients treated with different HMG-CoA reductase inhibitors (statins).Design Population based cohort…”
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Opioid dose and risk of road trauma in Canada: a population-based study by Gomes, Tara, Redelmeier, Donald A, Juurlink, David N, Dhalla, Irfan A, Camacho, Ximena, Mamdani, Muhammad M

“…Use of opioids may predispose drivers to road trauma, yet the effect of opioid dose on this association is unknown. We conducted a population-based nested…”
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