Search Results - "MALONEY, Katherine N"
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Radicinin from Cochliobolus sp. inhibits Xylella fastidiosa, the causal agent of Pierce’s Disease of grapevine
Published in Phytochemistry (Oxford) (01-08-2015)“…Radicinin (1) produced by a strain of Cochliobolus sp. isolated from grapevine inhibits Xylella fastidiosa in vitro, suggesting a possible mechanism for…”
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Bisandrographolide from Andrographis paniculata Activates TRPV4 Channels
Published in The Journal of biological chemistry (06-10-2006)“…Many transient receptor potential (TRP) channels are activated or blocked by various compounds found in plants; two prominent examples include the activation…”
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Significant Natural Product Biosynthetic Potential of Actinorhizal Symbionts of the Genus Frankia, as Revealed by Comparative Genomic and Proteomic Analyses
Published in Applied and Environmental Microbiology (01-06-2011)“…Classifications Services AEM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Antartin, a Cytotoxic Zizaane-Type Sesquiterpenoid from a Streptomyces sp. Isolated from an Antarctic Marine Sediment
Published in Marine drugs (16-04-2018)“…Antartin ( ), a new zizaane-type sesquiterpene, was isolated from sp. SCO736. The chemical structure of was assigned from the interpretation of 1D and 2D NMR…”
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Activity of the streptogramin antibiotic etamycin against methicillin-resistant Staphylococcus aureus
Published in Journal of antibiotics (01-05-2010)“…The alarming rise of hospital- and community-associated methicillin-resistant Staphylococcus aureus (HA- and CA-MRSA) infections has prompted a desperate…”
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Phaeosphaeride A, an Inhibitor of STAT3-Dependent Signaling Isolated from an Endophytic Fungus
Published in Organic letters (31-08-2006)“…Phaeosphaeride A, a nitrogen-containing bicyclic compound produced by an endophytic fungus, inhibits signaling by the transcription factor STAT3…”
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Actin-Aggregating Cucurbitacins from Physocarpus capitatus
Published in Journal of natural products (Washington, D.C.) (01-11-2008)“…Bioassay-guided fractionation of Physocarpus capitatus yielded two new cucurbitacins (3 and 4) along with the known cucurbitacin F (1) and dihydrocucurbitacin…”
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An In Vitro Pipeline for Screening and Selection of Citrus-Associated Microbiota with Potential Anti-" Candidatus Liberibacter asiaticus" Properties
Published in Applied and environmental microbiology (01-04-2020)“…Huanglongbing (HLB) is a destructive citrus disease that is lethal to all commercial citrus plants, making it the most serious citrus disease and one of the…”
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GNPS Dashboard: collaborative exploration of mass spectrometry data in the web browser
Published in Nature methods (01-02-2022)“…Access to web-based platforms has enabled scientists to perform research remotely. A critical aspect of mass spectrometry data analysis is the inspection,…”
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Gene expression signature-based chemical genomic prediction identifies a novel class of HSP90 pathway modulators
Published in Cancer cell (01-10-2006)“…Although androgen receptor (AR)-mediated signaling is central to prostate cancer, the ability to modulate AR signaling states is limited. Here we establish a…”
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Synthesis of Deoxyradicinin, an Inhibitor of Xylella fastidiosa and Liberibacter crescens, a Culturable Surrogate for Candidatus Liberibacter asiaticus
Published in Journal of natural products (Washington, D.C.) (26-06-2020)“…Pierce’s disease of grapevine and citrus huanglongbing are caused by the bacterial pathogens Xylella fastidiosa and Candidatus Liberibacter asiaticus (CLas),…”
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Cryptic Species Account for the Seemingly Idiosyncratic Secondary Metabolism of Sarcophyton glaucum Specimens Collected in Palau
Published in Journal of natural products (Washington, D.C.) (27-03-2020)“…Sarcophyton glaucum is one of the most abundant and chemically studied soft corals with over 100 natural products reported in the literature, primarily…”
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Lodopyridone, a Structurally Unprecedented Alkaloid from a Marine Actinomycete
Published in Organic letters (03-12-2009)“…Chemical examination of the secondary metabolites of a marine Saccharomonospora sp., isolated from marine sediments collected at the mouth of the La Jolla…”
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Fijimycins A–C, three antibacterial etamycin-class depsipeptides from a marine-derived Streptomyces sp
Published in Bioorganic & medicinal chemistry (15-11-2011)“…Three new depsipeptides, fijimycins A–C (1–3), together with the known etamycin A (4), were isolated and identified from the fermentation broth of strain…”
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Auto-deconvolution and molecular networking of gas chromatography–mass spectrometry data
Published in Nature biotechnology (01-02-2021)“…We engineered a machine learning approach, MSHub, to enable auto-deconvolution of gas chromatography–mass spectrometry (GC–MS) data. We then designed workflows…”
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A community resource for paired genomic and metabolomic data mining
Published in Nature chemical biology (01-04-2021)“…Genomics and metabolomics are widely used to explore specialized metabolite diversity. The Paired Omics Data Platform is a community initiative to…”
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Canvass: A Crowd-Sourced, Natural-Product Screening Library for Exploring Biological Space
Published in ACS central science (26-12-2018)“…Natural products and their derivatives continue to be wellsprings of nascent therapeutic potential. However, many laboratories have limited resources for…”
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