Search Results - "MALMSTRÖM, V."

Kidney infiltrating NK cells and NK-like T-cells in lupus nephritis: presence, localization, and the effect of immunosuppressive treatment by Scheffschick, Andrea, Fuchs, Sina, Malmström, Vivianne, Gunnarsson, Iva, Brauner, Hanna

“…Systemic lupus erythematosus (SLE) is a multi-organ inflammatory disease with kidney inflammation, lupus nephritis (LN), being one of the most severe…”
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Autoantibodies to citrullinated proteins induce joint pain independent of inflammation via a chemokine-dependent mechanism by Wigerblad, Gustaf, Bas, Duygu B, Fernades-Cerqueira, Cátia, Krishnamurthy, Akilan, Nandakumar, Kutty Selva, Rogoz, Katarzyna, Kato, Jungo, Sandor, Katalin, Su, Jie, Jimenez-Andrade, Juan Miguel, Finn, Anja, Bersellini Farinotti, Alex, Amara, Khaled, Lundberg, Karin, Holmdahl, Rikard, Jakobsson, Per-Johan, Malmström, Vivianne, Catrina, Anca I, Klareskog, Lars, Svensson, Camilla I

“…An interesting and so far unexplained feature of chronic pain in autoimmune disease is the frequent disconnect between pain and inflammation. This is…”
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Rheumatoid Arthritis-Specific Autoimmunity in the Lung Before and at the Onset of Disease by Joshua, Vijay, Loberg Haarhaus, Malena, Hensvold, Aase, Wähämaa, Heidi, Gerstner, Christina, Hansson, Monika, Israelsson, Lena, Stålesen, Ragnhild, Sköld, Magnus, Grunewald, Johan, Klareskog, Lars, Grönwall, Caroline, Réthi, Bence, Catrina, Anca, Malmström, Vivianne

“…The lung is implicated as a site for breach of tolerance prior to onset of seropositive rheumatoid arthritis (RA). To substantiate this, we investigated…”
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Specific interaction between genotype, smoking and autoimmunity to citrullinated α-enolase in the etiology of rheumatoid arthritis by Padyukov, Leonid, Lundberg, Karin, Symmons, Deborah P M, Ding, Bo, Fisher, Benjamin A, Alfredsson, Lars, Malmström, Vivianne, Mahdi, Hiba, Klareskog, Lars, Charles, Peter, Venables, Patrick J, Rönnelid, Johan, Plant, Darren, Källberg, Henrik

“…Gene-environment associations are important in rheumatoid arthritis (RA) susceptibility, with an association existing between smoking, HLA- DRB1 'shared…”
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Identification of proteinase 3 autoreactive CD4 + T cells and their T-cell receptor repertoires in antineutrophil cytoplasmic antibody-associated vasculitis by Sharma, Ravi Kumar, Yoosuf, Niyaz, Afonso, Marcelo, Scheffschick, Andrea, Avik, Aune, Bartoletti, Alice, Horuluoglu, Begum, Diaz Boada, Juan Sebastian, Boddul, Sanjay Kumar, Jonasdottir, Asta Dögg, Lövström, Björn, Brauner, Hanna, Raposo, Bruno, Chemin, Karine, Bruchfeld, Annette, Gunnarsson, Iva, Malmström, Vivianne

“…Antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is an autoimmune disease involving autoreactivity to proteinase 3 (PR3) as demonstrated…”
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The human bone marrow plasma cell compartment in rheumatoid arthritis - Clonal relationships and anti-citrulline autoantibody producing cells by Hensvold, Aase, Horuluoglu, Begum, Sahlström, Peter, Thyagarajan, Radha, Diaz Boada, Juan Sebastian, Hansson, Monika, Mathsson-Alm, Linda, Gerstner, Christina, Sippl, Natalie, Israelsson, Lena, Wedin, Rikard, Steen, Johanna, Klareskog, Lars, Réthi, Bence, Catrina, Anca I., Diaz-Gallo, Lina-Marcela, Malmström, Vivianne, Grönwall, Caroline

“…A majority of circulating IgG is produced by plasma cells residing in the bone marrow (BM). Long-lived BM plasma cells constitute our humoral immune memory and…”
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Late-onset neutropenia after rituximab in ANCA-associated vasculitis by Knight, A, Sundström, Y, Börjesson, O, Bruchfeld, A, Malmström, V, Gunnarsson, I

“…Background: Rituximab (RTX) is being used increasingly in anti-neutrophil cytoplasmatic antibody (ANCA)-associated vasculitis (AAV). Late-onset neutropenia…”
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Arthritis in systemic lupus erythematosus is characterized by local IL‐17A and IL‐6 expression in synovial fluid by Sippl, N., Faustini, F., Rönnelid, J., Turcinov, S., Chemin, K., Gunnarsson, I., Malmström, V.

“…Summary Arthritis is a common clinical feature of systemic lupus erythematosus (SLE) and is usually non‐erosive, as opposed to rheumatoid arthritis (RA). While…”
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A Refined Protocol for Identifying Citrulline-specific Monoclonal Antibodies from Single Human B Cells from Rheumatoid Arthritis Patient Material by Amara, Khaled, Israelsson, Lena, Stålesen, Ragnhild, Sahlström, Peter, Steen, Johanna, Malmström, Vivianne, Grönwall, Caroline

“…We describe here a detailed, refined protocol for the generation of citrulline-specific monoclonal antibodies from single human B cells from rheumatoid…”
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An optimized Protocol for Human M2 Macrophages using M‐CSF and IL‐4/IL‐10/TGF‐β Yields a Dominant Immunosuppressive Phenotype by Mia, S., Warnecke, A., Zhang, X.‐M., Malmström, V., Harris, R. A.

“…Monocytes are highly abundant circulatory effector cells and play a vital role in driving or resolving inflammatory processes depending on their activation…”
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Peripheral and site-specific CD4(+) CD28(null) T cells from rheumatoid arthritis patients show distinct characteristics by Pieper, J, Johansson, S, Snir, O, Linton, L, Rieck, M, Buckner, J H, Winqvist, O, van Vollenhoven, R, Malmström, V

“…Proinflammatory CD4(+) CD28(null) T cells are frequently found in the circulation of patients with rheumatoid arthritis (RA), but are less common in the…”
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Evaluation of B lymphocyte stimulator and a proliferation inducing ligand as candidate biomarkers in lupus nephritis based on clinical and histopathological outcome following induction therapy by Parodis, Ioannis, Zickert, Agneta, Sundelin, Birgitta, Axelsson, Magnus, Gerhardsson, Jakob, Svenungsson, Elisabet, Malmström, Vivianne, Gunnarsson, Iva

“…Objectives Lupus nephritis (LN) is a major cause of morbidity in patients with systemic lupus erythematosus (SLE). B cells have a central role in the…”
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IL‐1R1 is expressed on both Helios+ and Helios−FoxP3+CD4+ T cells in the rheumatic joint by Müller, M., Herrath, J., Malmström, V.

“…Summary Synovial fluid from rheumatic joints displays a well‐documented enrichment of forkhead box protein 3 (FoxP3)+ regulatory T cells (tissue Tregs)…”
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Multiple antibody reactivities to citrullinated antigens in sera from patients with rheumatoid arthritis: association with HLA-DRB1 alleles by Snir, O, Widhe, M, von Spee, C, Lindberg, J, Padyukov, L, Lundberg, K, Engström, A, Venables, P J, Lundeberg, J, Holmdahl, R, Klareskog, L, Malmström, V

“…Autoantibodies to cyclic citrullinated peptides (anti-CCP) are present in most patients with rheumatoid arthritis (RA), and associate with HLA-DRB1 shared…”
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Pentraxin-3 - a potential biomarker in ANCA-associated vasculitis by Jonasdottir, AD, Antovic, A, Qureshi, AR, Nordin, A, Malmström, V, Gunnarsson, I, Bruchfeld, A

“…The aim of this study was to investigate pentraxin-3 (PTX3) as a potential biomarker of inflammatory activity in patients with anti-neutrophil cytoplasmic…”
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Rituximab-mediated late-onset neutropenia in systemic lupus erythematosus – distinct roles of BAFF and APRIL by Parodis, I, Söder, F, Faustini, F, Kasza, Z, Samuelsson, I, Zickert, A, Svenungsson, E, van Vollenhoven, R F, Malmström, V, Wermeling, F, Gunnarsson, I

“…Objective Rituximab-mediated late-onset neutropenia (LON) has been described in various diseases. We investigated its occurrence, consequences and contributing…”
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Detection of human cytomegalovirus in synovial neutrophils obtained from patients with rheumatoid arthritis by Xu, X, Estekizadeh, A, Davoudi, B, Varani, S, Malmström, V, Rahbar, A, Söderberg-Nauclér, C

“…To examine whether signs of an active human cytomegalovirus (HCMV) infection are present in affected joints of patients with rheumatoid arthritis (RA)…”
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GPA and MPA patients have different serum cytokine profiles by Avik, A., Sundström, Y., Berg, L., Bruchfeld, A., Malmström, V., Gunnarsson, I.

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Modulating co-stimulation: a rational strategy in the treatment of rheumatoid arthritis? by Malmström, Vivianne, Trollmo, Christina, Klareskog, Lars

“…Rheumatoid arthritis (RA) is a common destructive inflammatory disease that affects 0.5-1% of the population in many countries. Even though several new…”
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Increased serum levels of B cell activating factor (BAFF) in subsets of patients with idiopathic inflammatory myopathies by Krystufková, O, Vallerskog, T, Helmers, S Barbasso, Mann, H, Putová, I, Belácek, J, Malmström, V, Trollmo, C, Vencovsky, J, Lundberg, I E

“…To investigate serum levels of B cell activating factor (BAFF) in patients with myositis and correlate these to autoantibody profile, clinical phenotype and…”
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