Search Results - "MALLET, Vincent"

OptiMol: Optimization of Binding Affinities in Chemical Space for Drug Discovery by Boitreaud, Jacques, Mallet, Vincent, Oliver, Carlos, Waldispühl, Jérôme

“…Ligand-based drug design has recently benefited from the development of deep generative models. These models enable extensive explorations of the chemical…”
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quicksom: Self-Organizing Maps on GPUs for clustering of molecular dynamics trajectories by Mallet, Vincent, Nilges, Michael, Bouvier, Guillaume

“…Abstract Summary We implemented the Self-Organizing Maps algorithm running efficiently on GPUs, and also provide several clustering methods of the resulting…”
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Inhibition of the dipeptidyl peptidase DPP4 (CD26) reveals IL-33-dependent eosinophil-mediated control of tumor growth by Hollande, Clémence, Boussier, Jeremy, Ziai, James, Nozawa, Tamaki, Bondet, Vincent, Phung, Wilson, Lu, Binfeng, Duffy, Darragh, Paradis, Valerie, Mallet, Vincent, Eberl, Gérard, Sandoval, Wendy, Schartner, Jill M., Pol, Stanislas, Barreira da Silva, Rosa, Albert, Matthew L.

“…Post-translational modification of chemokines mediated by the dipeptidyl peptidase DPP4 (CD26) has been shown to negatively regulate lymphocyte trafficking,…”
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Mental disorders, COVID-19-related life-saving measures and mortality in France: A nationwide cohort study by Schwarzinger, Michaël, Luchini, Stéphane, Teschl, Miriam, Alla, François, Mallet, Vincent, Rehm, Jürgen

“…Meta-analyses have shown that preexisting mental disorders may increase serious Coronavirus Disease 2019 (COVID-19) outcomes, especially mortality. However,…”
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Ribavirin for Chronic Hepatitis E Virus Infection in Transplant Recipients by Kamar, Nassim, Izopet, Jacques, Tripon, Simona, Bismuth, Michael, Hillaire, Sophie, Dumortier, Jérôme, Radenne, Sylvie, Coilly, Audrey, Garrigue, Valérie, D'Alteroche, Louis, Buchler, Matthias, Couzi, Lionel, Lebray, Pascal, Dharancy, Sebastien, Minello, Anne, Hourmant, Maryvonne, Roque-Afonso, Anne-Marie, Abravanel, Florence, Pol, Stanislas, Rostaing, Lionel, Mallet, Vincent

“…Hepatitis E virus may cause chronic infection in certain patients, such as those who are immunocompromised. In this report from France involving 59 solid-organ…”
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Alcohol use disorders and associated chronic disease - a national retrospective cohort study from France by Schwarzinger, Michaël, Thiébaut, Sophie Pascale, Baillot, Sylvain, Mallet, Vincent, Rehm, Jürgen

“…Evidence on diseases caused by or associated with alcohol use disorders (AUDs) has been based on two meta-analyses including rather dated studies. The…”
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Noninvasive In Vivo Liver Fibrosis Evaluation Using Supersonic Shear Imaging: A Clinical Study on 113 Hepatitis C Virus Patients by Bavu, Éric, Gennisson, Jean-Luc, Couade, Mathieu, Bercoff, Jeremy, Mallet, Vincent, Fink, Mathias, Badel, Anne, Vallet-Pichard, AnaÏs, Nalpas, Bertrand, Tanter, Mickaël, Pol, Stanislas

“…Abstract Supersonic shear imaging (SSI) has recently been demonstrated to be a repeatable and reproducible transient bidimensional elastography technique. We…”
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Brief Communication: Case Reports of Ribavirin Treatment for Chronic Hepatitis E by MALLET, Vincent, NICAND, Elisabeth, SULTANIK, Philippe, CHAKVETADZE, Catherine, TESSE, Sophie, THERVET, Eric, MOUTHON, Luc, SOGNI, Philippe, POL, Stanislas

“…There is currently no accepted treatment of chronic hepatitis E virus (HEV) infection. To report 2 patients in whom ribavirin therapy seemed to alter the…”
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Hepatitis E transmission by transfusion of Intercept blood system–treated plasma by Hauser, Lisette, Roque-Afonso, Anne-Marie, Beylouné, Alexandre, Simonet, Marion, Deau Fischer, Bénédicte, Burin des Roziers, Nicolas, Mallet, Vincent, Tiberghien, Pierre, Bierling, Philippe

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Management of viral hepatitis in patients with haematological malignancy and in patients undergoing haemopoietic stem cell transplantation: recommendations of the 5th European Conference on Infections in Leukaemia (ECIL-5) by Mallet, Vincent, Prof, van Bömmel, Florian, MD, Doerig, Christopher, MD, Pischke, Sven, MD, Hermine, Olivier, Prof, Locasciulli, Anna, Prof, Cordonnier, Catherine, Prof, Berg, Thomas, Prof, Moradpour, Darius, Prof, Wedemeyer, Heiner, Prof, Ljungman, Per, Prof

“…Summary Viral hepatitis affects millions of people worldwide, and host immunity is the key determinant of patient outcome. Viral hepatitis can be life…”
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Transfusion-Transmitted Hepatitis E Virus Infection in France by Gallian, Pierre, Pouchol, Elodie, Djoudi, Rachid, Lhomme, Sébastien, Mouna, Lina, Gross, Sylvie, Bierling, Philippe, Assal, Azzedine, Kamar, Nassim, Mallet, Vincent, Roque-Afonso, Anne-Marie, Izopet, Jacques, Tiberghien, Pierre

“…There is growing concern regarding the risk of transfusion- transmitted (TT) hepatitis E. Since the first described case in 2006, several TT hepatitis E have…”
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Brief Communication : The Relationship of Regression of Cirrhosis to Outcome in Chronic Hepatitis C by MALLET, Vincent, GILGENKRANTZ, Hélène, SERPAGGI, Jeanne, VERKARRE, Virginie, VALLET-PICHARD, Anats, FONTAINE, Hélène, POL, Stanislas, BLACK, Martin, THOMAS, Rebecca

“…The effect of regression of cirrhosis in chronic hepatitis C is unknown. To evaluate the relation between regression of cirrhosis and clinical outcome in…”
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Management of Hepatitis B Virus and Hepatitis C Virus Infections in Patients with Cancer Receiving Immune Checkpoint Inhibitors by Mustafayev, Khalis, Mallet, Vincent, Torres, Harrys A

“…Patients with cancer with hepatitis B virus (HBV) or hepatitis C virus (HCV) infection are excluded from many cancer clinical trials of immune checkpoint…”
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Dual Role of CCR2 in the Constitution and the Resolution of Liver Fibrosis in Mice by Mitchell, Claudia, Couton, Dominique, Couty, Jean-Pierre, Anson, Marie, Crain, Anne-Marie, Bizet, Vinciane, Rénia, Laurent, Pol, Stanislas, Mallet, Vincent, Gilgenkrantz, Hélène

“…Inflammation has been shown to induce the progression of fibrosis in response to liver injury. Among inflammatory cells, macrophages and lymphocytes play major…”
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Association between hydroxocobalamin administration and acute kidney injury after smoke inhalation: a multicenter retrospective study by Dépret, François, Hoffmann, Clément, Daoud, Laura, Thieffry, Camille, Monplaisir, Laure, Creveaux, Jules, Annane, Djillali, Parmentier, Erika, Mathieu, Daniel, Wiramus, Sandrine, Demeure DIt Latte, Dominique, Kpodji, Aubin, Textoris, Julien, Robin, Florian, Klouche, Kada, Pontis, Emmanuel, Schnell, Guillaume, Barbier, François, Constantin, Jean-Michel, Clavier, Thomas, du Cheyron, Damien, Terzi, Nicolas, Sauneuf, Bertrand, Guerot, Emmanuel, Lafon, Thomas, Herbland, Alexandre, Megarbane, Bruno, Leclerc, Thomas, Mallet, Vincent, Pirracchio, Romain, Legrand, Matthieu

“…The use of hydroxocobalamin has long been advocated for treating suspected cyanide poisoning after smoke inhalation. Intravenous hydroxocobalamin has however…”
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Should we await IFN-free regimens to treat HCV genotype 1 treatment-naive patients? A cost-effectiveness analysis (ANRS 95141) by Deuffic-Burban, Sylvie, Schwarzinger, Michaël, Obach, Dorothée, Mallet, Vincent, Pol, Stanislas, Pageaux, Georges-Philippe, Canva, Valérie, Deltenre, Pierre, Roudot-Thoraval, Françoise, Larrey, Dominique, Dhumeaux, Daniel, Mathurin, Philippe, Yazdanpanah, Yazdan

“…Background & Aims In treatment-naive patients mono-infected with genotype 1 chronic HCV, treatments with telaprevir/boceprevir (TVR/BOC)-based triple therapy…”
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AlignScape, displaying sequence similarity using self-organizing maps by Filella-Merce, Isaac, Mallet, Vincent, Durand, Eric, Nilges, Michael, Bouvier, Guillaume, Pellarin, Riccardo

“…The current richness of sequence data needs efficient methodologies to display and analyze the complexity of the information in a compact and readable manner…”
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Inhibition of DPP4 activity in humans establishes its in vivo role in CXCL10 post‐translational modification: prospective placebo‐controlled clinical studies by Decalf, Jérémie, Tarbell, Kristin V, Casrouge, Armanda, Price, Jeffrey D, Linder, Grace, Mottez, Estelle, Sultanik, Philippe, Mallet, Vincent, Pol, Stanislas, Duffy, Darragh, Albert, Matthew L

“…Biochemical experiments, animal models, and observational studies in humans all support a role of dipeptidyl peptidase 4 (DPP4) in the N‐terminal truncation of…”
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Chronic Hepatitis E in Rheumatology and Internal Medicine Patients: A Retrospective Multicenter European Cohort Study by Pischke, Sven, Peron, Jean-Marie, von Wulffen, Moritz, von Felden, Johann, Höner Zu Siederdissen, Christoph, Fournier, Sophie, Lütgehetmann, Marc, Iking-Konert, Christoph, Bettinger, Dominik, Par, Gabriella, Thimme, Robert, Cantagrel, Alain, Lohse, Ansgar W, Wedemeyer, Heiner, de Man, Robert, Mallet, Vincent

“…Hepatitis E virus (HEV) infection is a pandemic with regional outbreaks, including in industrialized countries. HEV infection is usually self-limiting but can…”
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Rapid Decline of Liver Stiffness Following Alcohol Withdrawal in Heavy Drinkers by Trabut, Jean-Baptiste, Thépot, Véronique, Nalpas, Bertrand, Lavielle, Béatrice, Cosconea, Simona, Corouge, Marion, Vallet-Pichard, Anaïs, Fontaine, Hélène, Mallet, Vincent, Sogni, Philippe, Pol, Stanislas

“…Background: Measurement of liver stiffness (LS) using real‐time elastography appears as a promising tool to evaluate the severity of chronic liver diseases…”
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