Search Results - "MALISON, Robert T"

Clinically Relevant Doses of Methylphenidate Significantly Occupy Norepinephrine Transporters in Humans In Vivo by Hannestad, Jonas, Gallezot, Jean-Dominique, Planeta-Wilson, Beata, Lin, Shu-Fei, Williams, Wendol A, van Dyck, Christopher H, Malison, Robert T, Carson, Richard E, Ding, Yu-Shin

“…Background Attention-deficit/hyperactivity disorder is a psychiatric disorder that starts in childhood. The mechanism of action of methylphenidate, the most…”
Get full text

Genome-wide meta-analysis of alcohol use disorder in East Asians by Zhou, Hang, Kalayasiri, Rasmon, Sun, Yan, Nuñez, Yaira Z, Deng, Hong-Wen, Chen, Xiang-Ding, Justice, Amy C, Kranzler, Henry R, Chang, Suhua, Lu, Lin, Shi, Jie, Sanichwankul, Kittipong, Mutirangura, Apiwat, Malison, Robert T, Gelernter, Joel

“…Alcohol use disorder (AUD) is a leading cause of death and disability worldwide. Genome-wide association studies (GWAS) have identified ~30 AUD risk genes in…”
Get full text

Reductions in Brain 5-HT1B Receptor Availability in Primarily Cocaine-Dependent Humans by Matuskey, David, Bhagwagar, Zubin, Planeta, Beata, Pittman, Brian, Gallezot, Jean-Dominique, Chen, Jason, Wanyiri, Jane, Najafzadeh, Soheila, Ropchan, Jim, Geha, Paul, Huang, Yiyun, Potenza, Marc N, Neumeister, Alexander, Carson, Richard E, Malison, Robert T

“…Background Preclinical evidence implicates the serotonin receptor 5-hydroxytryptamine 1B (5-HT1B ) in the effects of cocaine. This study explores 5-HT1B in…”
Get full text

Gray‐matter relationships to diagnostic and transdiagnostic features of drug and behavioral addictions by Yip, Sarah W., Worhunsky, Patrick D., Xu, Jiansong, Morie, Kristen P., Constable, R. Todd, Malison, Robert T., Carroll, Kathleen M., Potenza, Marc N.

“…Alterations in neural structure have been reported in both cocaine‐use disorder and gambling disorder, separately, suggesting similarities across addiction…”
Get full text

Age-related changes in binding of the D2/3 receptor radioligand [11C](+)PHNO in healthy volunteers by Matuskey, David, Worhunksy, Patrick, Correa, Elizabeth, Pittman, Brian, Gallezot, Jean-Dominique, Nabulsi, Nabeel, Ropchan, Jim, Sreeram, Venkatesh, Gudepu, Rohit, Gaiser, Edward, Cosgrove, Kelly, Ding, Yu-Shin, Potenza, Marc N., Huang, Yiyun, Malison, Robert T., Carson, Richard E.

“…Previous imaging studies with positron emission tomography (PET) have reliably demonstrated an age-associated decline in the dopamine system. Most of these…”
Get full text

Genome-wide association study of alcohol dependence in male Han Chinese and cross-ethnic polygenic risk score comparison by Sun, Yan, Chang, Suhua, Wang, Fan, Sun, Hongqiang, Ni, Zhaojun, Yue, Weihua, Zhou, Hang, Gelernter, Joel, Malison, Robert T., Kalayasiri, Rasmon, Wu, Ping, Lu, Lin, Shi, Jie

“…Alcohol-related behaviors are moderately heritable and have ethnic-specific characteristics. At present, genetic studies for alcohol dependence (AD) in Chinese…”
Get full text

Riluzole Augmentation in Treatment-Resistant Obsessive–Compulsive Disorder: An Open-Label Trial by Coric, Vladimir, Taskiran, Sarper, Pittenger, Christopher, Wasylink, Suzanne, Mathalon, Daniel H., Valentine, Gerald, Saksa, John, Wu, Yu-te, Gueorguieva, Ralitza, Sanacora, Gerard, Malison, Robert T., Krystal, John H.

“…Most patients with obsessive–compulsive disorder (OCD) show only partial reduction of symptoms with standard therapy. Recent imaging data suggests…”
Get full text

Biological markers of the effects of intravenous methylphenidate on improving inhibitory control in cocaine-dependent patients by Li, Chiang-shan R., Morgan, Peter T., Matuskey, David, Abdelghany, Osama, Luo, Xi, Chang, Jeremy L. K., Rounsaville, Bruce J., Ding, Yu-shin, Malison, Robert T., Ito, Masao

“…Prior research points to the importance of psychostimulants in improving self-control. However, the neural substrates underlying such improvement remain…”
Get full text

PET imaging of the effects of age and cocaine on the norepinephrine transporter in the human brain using (S,S)-[11C]O-methylreboxetine and HRRT by Ding, Yu-Shin, Singhal, Tarun, Planeta-Wilson, Beata, Gallezot, Jean-Dominique, Nabulsi, Nabeel, Labaree, David, Ropchan, Jim, Henry, Shannan, Williams, Wendol, Carson, Richard E., Neumeister, Alexander, Malison, Robert T.

“…Objectives: The role of the norepinephrine transporter (NET) in cocaine dependence has never been demonstrated via in vivo imaging due to the lack of suitable…”
Get full text

Ancestry informative markers for distinguishing between Thai populations based on genome-wide association datasets by Vongpaisarnsin, Kornkiat, Listman, Jennifer Beth, Malison, Robert T, Gelernter, Joel

“…Highlights • A total of 124 AIMs markedly cluster the major geographic continents. • 89 AIMs could stratify Thai from East Asian populations. • 273 AIMs…”
Get full text

Shared microstructural features of behavioral and substance addictions revealed in areas of crossing fibers by Yip, Sarah W., PhD, Morie, Kristen P., PhD, Xu, Jiansong, MD, PhD, Constable, R. Todd, PhD, Malison, Robert T., MD, Carroll, Kathleen M., PhD, Potenza, Marc N., MD, PhD

“…Abstract Background Similarities between behavioral and substance addictions exist. However, direct neurobiological comparison between addictive disorders is…”
Get full text

Cocaine dependence and thalamic functional connectivity: a multivariate pattern analysis by Zhang, Sheng, Hu, Sien, Sinha, Rajita, Potenza, Marc N, Malison, Robert T, Li, Chiang-Shan R

“…Cocaine dependence is associated with deficits in cognitive control. Previous studies demonstrated that chronic cocaine use affects the activity and functional…”
Get full text

Age-related decline in dopamine transporters: analysis of striatal subregions, nonlinear effects, and hemispheric asymmetries by van Dyck, Christopher H, Seibyl, John P, Malison, Robert T, Laruelle, Marc, Zoghbi, Sami S, Baldwin, Ronald M, Innis, Robert B

“…Neuroimaging studies have documented an age-related decline in striatal dopamine transporters (DATs) as a marker of dopaminergic neurodegeneration. The authors…”
Get more information

Deficits in prefrontal cortical and extrastriatal dopamine release in schizophrenia: a positron emission tomographic functional magnetic resonance imaging study by Slifstein, Mark, van de Giessen, Elsmarieke, Van Snellenberg, Jared, Thompson, Judy L, Narendran, Rajesh, Gil, Roberto, Hackett, Elizabeth, Girgis, Ragy, Ojeil, Najate, Moore, Holly, D'Souza, Deepak, Malison, Robert T, Huang, Yiyun, Lim, Keunpoong, Nabulsi, Nabeel, Carson, Richard E, Lieberman, Jeffrey A, Abi-Dargham, Anissa

“…Multiple lines of evidence suggest a deficit in dopamine release in the prefrontal cortex (PFC) in schizophrenia. Despite the prevalence of the concept of…”
Get more information

Cocaine and sleep: early abstinence by Morgan, Peter T, Malison, Robert T

“…Compulsive cocaine use is associated with a profound dysregulation of sleep. Perhaps the result of chronic use, a significant deterioration in sleep is…”
Get full text

Brain Activity During Cocaine Craving and Gambling Urges: An fMRI Study by Kober, Hedy, Lacadie, Cheryl M, Wexler, Bruce E, Malison, Robert T, Sinha, Rajita, Potenza, Marc N

“…Although craving states are important to both cocaine dependence (CD) and pathological gambling (PG), few studies have directly investigated neurobiological…”
Get full text

An exploratory examination of marijuana use, problem-gambling severity, and health correlates among adolescents by Hammond, Christopher J, Pilver, Corey E, Rugle, Loreen, Steinberg, Marvin A, Mayes, Linda C, Malison, Robert T, Krishnan-Sarin, Suchitra, Hoff, Rani A, Potenza, Marc N

“…Gambling is common in adolescents and at-risk and problem/pathological gambling (ARPG) is associated with adverse measures of health and functioning in this…”
Get full text

Clinical features of methamphetamine-induced paranoia and preliminary genetic association with DBH-1021C→T in a Thai treatment cohort by Kalayasiri, Rasmon, Verachai, Viroj, Gelernter, Joel, Mutirangura, Apiwat, Malison, Robert T.

“…Aims To explore the clinical features of methamphetamine‐induced paranoia (MIP) and associations between MIP and a genetic polymorphism in dopamine…”
Get full text

Testing the effects of the GLP-1 receptor agonist exenatide on cocaine self-administration and subjective responses in humans with cocaine use disorder by Angarita, Gustavo A., Matuskey, David, Pittman, Brian, Costeines, Jessica L., Potenza, Marc N., Jastreboff, Ania M., Schmidt, Heath D., Malison, Robert T.

“…•The effects of a GLP-1 agonist (exenatide) on behavioral and subjective effects of cocaine were examined.•All subjects participated in a self-regulated…”
Get full text

Genomewide Association Study of Alcohol Dependence and Related Traits in a Thai Population by Gelernter, Joel, Zhou, Hang, Nuñez, Yaira Z., Mutirangura, Apiwat, Malison, Robert T., Kalayasiri, Rasmon

“…Background Alcohol use (both quantity and dependence) is moderately heritable, and genomewide association studies (GWAS) have identified risk genes in…”
Get full text