Haemodynamic effects and the visibility of the surgical field after lidocaine infiltration during septoplasty under general anaesthesia

Background and Purpose: The aim of this study was to determine the effect of local infiltration of adrenaline- containing lidocaine solution during septoplasty under general anaesthesia on systemic haemodynamics and the visibility of the operative field, and to compare it to the topical application...

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Bibliographic Details
Published in:	Periodicum biologorum Vol. 111; no. 2; p. 267
Main Authors:	GORANOVIĆ, TATJANA, MILIĆ, MORENA, PARAZAJDER, DOMAGOJ, AVDAGIĆ, ESAD, NENADIĆ, DENIS, VUČKOVIĆ, BRANIMIR, MALDINI1, BRANKA, ŠAKIĆ, KATARINA
Format:	Web Resource
Language:	English
Published:	Hrvatsko prirodoslovno društvo 15-06-2009
Subjects:	Adrenaline Anesthesia Ephedrine Lidocaine local Nasal septum Surgical procedures
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Summary:	Background and Purpose: The aim of this study was to determine the effect of local infiltration of adrenaline- containing lidocaine solution during septoplasty under general anaesthesia on systemic haemodynamics and the visibility of the operative field, and to compare it to the topical application of ephedrine. Patients and Methods: A retrospective, comparative, non-randomised, open study on 72 ASA physical status I and II patients, aged 20 to 73 years, scheduled for septoplasty was performed. Lidocaine/adrenaline-ephedrine group (group LA-E; n=18) received four cotton pledgets soaked with 1 % ephedrine, and then the submucosal infiltration of 2% lidocaine containing adrenaline solution (2ml) plus plain 2% lidocaine solution (5ml). Lidocaine/ adrenaline group (LA group; n=25) received the submucosal infiltration of 2% lidocaine containing adrenaline solution (2ml) plus plain 2% lidocaine solution (5ml). Ephedrine group (E group; n=29) received four cotton pledgets soaked with 1% ephedrine. Heart rate (HR) and mean arterial pressure (MAP) were recorded at predetermined time intervals. Bleeding in the surgical field was rated according to a 6-point scale. Results: LA and LA-E groups showed significant lower HR and MAP compared to E-group. LA group showed only slight oscillations in HR. Average bleeding score was 2.28±0.83 in LA-E, 2.08±0.81 in LA and 3.14±0.74 in E group (p<0.001). Conclusions:We demonstrated that infiltration of lidocaine with adrenaline has statistically and clinically better impact on systemic haemodynamics and visibility of the surgical field than that achieved by topical application of ephedrine alone.
Bibliography:	38242
ISSN:	0031-5362 1849-0964