Search Results - "MALAWISTA, STEPHEN E"

Infection-induced NETosis is a dynamic process involving neutrophil multitasking in vivo by Yipp, Bryan G, Petri, Björn, Salina, Davide, Jenne, Craig N, Scott, Brittney N V, Zbytnuik, Lori D, Pittman, Keir, Asaduzzaman, Muhammad, Wu, Kaiyu, Meijndert, H Christopher, Malawista, Stephen E, de Boisfleury Chevance, Anne, Zhang, Kunyan, Conly, John, Kubes, Paul

“…Bacteria can be trapped by neutrophil extracellular traps (NETs) in vitro , but their relevance in vivo is uncertain, in part because NETs are thought to be…”
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Dysregulation of TLR3 Impairs the Innate Immune Response to West Nile Virus in the Elderly by KONG, Kok-Fai, DELROUX, Karine, XIAOMEI WANG, FENG QIAN, ARJONA, Alvaro, MALAWISTA, Stephen E, FIKRIG, Erol, MONTGOMERY, Ruth R

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Anaplasma phagocytophilum induces actin phosphorylation to selectively regulate gene transcription in Ixodes scapularis ticks by Sultana, Hameeda, Neelakanta, Girish, Kantor, Fred S, Malawista, Stephen E, Fish, Durland, Montgomery, Ruth R, Fikrig, Erol

“…Anaplasma phagocytophilum, the agent of human anaplasmosis, persists in ticks and mammals. We show that A. phagocytophilum induces the phosphorylation of actin…”
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Reduced bioenergetics and toll-like receptor 1 function in human polymorphonuclear leukocytes in aging by Qian, Feng, Guo, Xiuyang, Wang, Xiaomei, Yuan, Xiaoling, Chen, Shu, Malawista, Stephen E, Bockenstedt, Linda K, Allore, Heather G, Montgomery, Ruth R

“…Aging is associated with a progressive decline in immune function (immunosenescence) resulting in an increased susceptibility to viral and bacterial…”
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Tonic inhibition of chemotaxis in human plasma by Malawista, Stephen E, de Boisfleury Chevance, Anne, van Damme, Jo, Serhan, Charles N

“…We found exaggerated chemotaxis in plasma treated with EDTA and thought that the EDTA might itself be inhibiting a tonic inhibitor(s) of chemotaxis. Our plasma…”
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Plunder of Human Blood Leukocytes Containing Ingested Material, by Other Leukocytes: Where Is the Fusagen That Allows Preservation of Membrane Integrity and Motile Function? by Malawista, Stephen E, Chevance de Boisfleury, Anne

“…In studying phagocytosis of zymosan particles by human blood monocytes in phase-contrast videomicroscopy, we found that monocytes loaded with zymosan particles…”
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Recruitment of Macrophages and Polymorphonuclear Leukocytes in Lyme Carditis by Montgomery, Ruth R, Booth, Carmen J, Wang, Xiaomei, Blaho, Victoria A, Malawista, Stephen E, Brown, Charles R

“…Lyme arthritis, caused by the spirochete Borrelia burgdorferi, can be recurrent or prolonged, whereas Lyme carditis is mostly nonrecurring. A prominent…”
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Calprotectin, an Abundant Cytosolic Protein from Human Polymorphonuclear Leukocytes, Inhibits the Growth of Borrelia burgdorferi by LUSITANI, Denise, MALAWISTA, Stephen E, MONTGOMERY, Ruth R

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Tick Saliva Reduces Adherence and Area of Human Neutrophils by MONTGOMERY, Ruth R, LUSITANI, Denise, DE BOISFLEURY CHEVANCE, Anne, MALAWISTA, Stephen E

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Clocking the Lyme spirochete by Malawista, Stephen E, de Boisfleury Chevance, Anne

“…In order to clear the body of infecting spirochetes, phagocytic cells must be able to get hold of them. In real-time phase-contrast videomicroscopy we were…”
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Recruitment of the cross-linked opsonic receptor CD32A (FcgammaRIIA) to high-density detergent-resistant membrane domains in human neutrophils by Rollet-Labelle, Emmanuelle, Marois, Sébastien, Barbeau, Kathy, Malawista, Stephen E, Naccache, Paul H

“…We have previously shown that CD32A (or FcgammaRIIA), one of the main opsonin receptors, was rapidly insolubilized and degraded in intact neutrophils after its…”
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Increased TLR4 expression and downstream cytokine production in immunosuppressed adults compared to non-immunosuppressed adults by Dunne, Dana W, Shaw, Albert, Bockenstedt, Linda K, Allore, Heather G, Chen, Shu, Malawista, Stephen E, Leng, Lin, Mizue, Yuka, Piecychna, Marta, Zhang, Lin, Towle, Virginia, Bucala, Richard, Montgomery, Ruth R, Fikrig, Erol

“…An increasing number of patients have medical conditions with altered host immunity or that require immunosuppressive medications. While immunosuppression is…”
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Borrelia burgdorferi Are Susceptible to Killing by a Variety of Human Polymorphonuclear Leukocyte Components by Lusitani, Denise, Malawista, Stephen E., Montgomery, Ruth R.

“…The killing of Borrelia burgdorferi by intact human polymorphonuclear leukocytes (PMNL) and by individual PMNL components was compared. Intact PMNL killed B…”
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Exploitation of Interleukin-8-Induced Neutrophil Chemotaxis by the Agent of Human Granulocytic Ehrlichiosis by AKKOYUNLU, Mustafa, MALAWISTA, Stephen E, ANGUITA, Juan, FIKRIG, Erol

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Human phagocytic cells in the early innate immune response to Borrelia burgdorferi by Montgomery, Ruth R., Lusitani, Denise, de Boisfleury Chevance, Anne, Malawista, Stephen E.

“…During natural infection with the agent of Lyme disease, Borrelia burgdorferi, polymorphonuclear leukocytes (PMNL) are the first cells of the innate immune…”
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On acute gouty arthritis by Malawista, Stephen E.

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Human Neutrophil Calprotectin Reduces the Susceptibility of Borrelia burgdorferi to Penicillin by Montgomery, Ruth R, Schreck, Kimberly, Wang, Xiaomei, Malawista, Stephen E

“…Borrelia burgdorferi, the spirochetal agent of Lyme disease, is susceptible to killing by a variety of polymorphonuclear leukocyte (PMN) components. Some are…”
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Inhibition of Borrelia burgdorferi-Tick Interactions In Vivo by Outer Surface Protein A Antibody by Pal, Utpal, Montgomery, Ruth R, Lusitani, Denise, Voet, Pierre, Weynants, Vincent, Malawista, Stephen E, Lobet, Yves, Fikrig, Erol

“…Borrelia burgdorferi outer surface protein (Osp) A is preferentially expressed by spirochetes in the Ixodes scapularis gut and facilitates pathogen-vector…”
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Superoxide Anion Production during Anaplasma phagocytophila Infection by Wang, Tian, Malawista, Stephen E., Pal, Utpal, Grey, Mark, Meek, James, Akkoyunlu, Mustafa, Thomas, Venetta, Fikrig, Erol

“…Anaplasma phagocytophila persists within neutrophils and prevents the respiratory burst by inhibiting$gp91^phox$. Mutations in$gp91^phox$result in chronic…”
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Random Locomotion and Chemotaxis of Human Blood Polymorphonuclear Leukocytes (PMN) in the Presence of EDTA: PMN in Close Quarters Require Neither Leukocyte Integrins nor External Divalent Cations by Malawista, Stephen E., Anne De Boisfleury Chevance

“…Divalent cations are thought essential for motile function of leukocytes in general, and for the function of critical adhesion molecules in particular. In the…”
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