Search Results - "MALAVAZI, Iran"
-
1
The dynamics and role of sphingolipids in eukaryotic organisms upon thermal adaptation
Published in Progress in lipid research (01-11-2020)“…All living beings have an optimal temperature for growth and survival. With the advancement of global warming, the search for understanding adaptive processes…”
Get full text
Journal Article -
2
Mitogen activated protein kinases SakAHOG1 and MpkC collaborate for Aspergillus fumigatus virulence
Published in Molecular microbiology (01-06-2016)“…Summary Here, we investigated which stress responses were influenced by the MpkC and SakA mitogen‐activated protein kinases of the high‐osmolarity glycerol…”
Get full text
Journal Article -
3
Aspergillus fumigatus mitogen-activated protein kinase MpkA is involved in gliotoxin production and self-protection
Published in Nature communications (02-01-2024)“…Aspergillus fumigatus is a saprophytic fungus that can cause a variety of human diseases known as aspergillosis. Mycotoxin gliotoxin (GT) production is…”
Get full text
Journal Article -
4
Aspergillus fumigatus calcium-responsive transcription factors regulate cell wall architecture promoting stress tolerance, virulence and caspofungin resistance
Published in PLoS genetics (01-12-2019)“…Aspergillus fumigatus causes invasive aspergillosis, the most common life-threatening fungal disease of immuno-compromised humans. The treatment of…”
Get full text
Journal Article -
5
Functional characterization of Cullin-1-RING ubiquitin ligase (CRL1) complex in Leishmania infantum
Published in PLoS pathogens (01-07-2024)“…Cullin-1-RING ubiquitin ligases (CRL1) or SCF1 (SKP1-CUL1-RBX1) E3 ubiquitin ligases are the largest and most extensively investigated class of E3 ligases in…”
Get full text
Journal Article -
6
Characterization of Aspergillus fumigatus Extracellular Vesicles and Their Effects on Macrophages and Neutrophils Functions
Published in Frontiers in microbiology (04-09-2019)“…Extracellular vesicles (EVs) has been considered an alternative process for intercellular communication. EVs release by filamentous fungi and the role of…”
Get full text
Journal Article -
7
Vaccination with Live or Heat-Killed Aspergillus fumigatus Δ sglA Conidia Fully Protects Immunocompromised Mice from Invasive Aspergillosis
Published in mBio (26-10-2022)“…Aspergillus fumigatus causes invasive aspergillosis (IA) in immunocompromised patients, resulting in high mortality rates. Currently, no vaccine formulations…”
Get full text
Journal Article -
8
Analyses of the three 1-Cys Peroxiredoxins from Aspergillus fumigatus reveal that cytosolic Prx1 is central to H2O2 metabolism and virulence
Published in Scientific reports (17-08-2018)“…Standing among the front defense strategies against pathogens, host phagocytic cells release various oxidants. Therefore, pathogens have to cope with stressful…”
Get full text
Journal Article -
9
Genomic islands in the pathogenic filamentous fungus Aspergillus fumigatus
Published in PLoS genetics (01-04-2008)“…We present the genome sequences of a new clinical isolate of the important human pathogen, Aspergillus fumigatus, A1163, and two closely related but rarely…”
Get full text
Journal Article -
10
Mitogen-Activated Protein Kinase Cross-Talk Interaction Modulates the Production of Melanins in Aspergillus fumigatus
Published in mBio (26-03-2019)“…The pathogenic fungus is able to adapt to extremely variable environmental conditions. The genome contains four genes coding for mitogen-activated protein…”
Get full text
Journal Article -
11
The Heat Shock Transcription Factor HsfA Is Essential for Thermotolerance and Regulates Cell Wall Integrity in Aspergillus fumigatus
Published in Frontiers in microbiology (09-04-2021)“…The deleterious effects of human-induced climate change have long been predicted. However, the imminent emergence and spread of new diseases, including fungal…”
Get full text
Journal Article -
12
Aspergillus fumigatus Transcription Factors Involved in the Caspofungin Paradoxical Effect
Published in mBio (16-06-2020)“…is the leading cause of pulmonary fungal diseases. Azoles have been used for many years as the main antifungal agents to treat and prevent invasive…”
Get full text
Journal Article -
13
Assessment of cecal microbiota modulation from piglet dietary supplementation with copper
Published in BMC microbiology (31-03-2023)“…Swine production expanded in the last decades. Efforts have been made to improve meat production and to understand its relationship to pig gut microbiota…”
Get full text
Journal Article -
14
First report of coexistence of blaKPC-2 and blaNDM-1 in carbapenem-resistant clinical isolates of Klebsiella aerogenes in Brazil
Published in Frontiers in microbiology (14-02-2024)“…is an important opportunistic pathogen with the potential to develop resistance against last-line antibiotics, such as carbapenems, limiting the treatment…”
Get full text
Journal Article -
15
Effects of low level laser therapy on inflammatory and angiogenic gene expression during the process of bone healing: A microarray analysis
Published in Journal of photochemistry and photobiology. B, Biology (01-01-2016)“…The process of bone healing as well as the expression of inflammatory and angiogenic genes after low level laser therapy (LLLT) were investigated in an…”
Get full text
Journal Article -
16
Characterization of KPC-Producing Serratia marcescens in an Intensive Care Unit of a Brazilian Tertiary Hospital
Published in Frontiers in microbiology (20-05-2020)“…Serratia marcescens has emerged as an important opportunistic pathogen responsible for nosocomial and severe infections. Here, we determined phenotypic and…”
Get full text
Journal Article -
17
Overview of the Interplay Between Cell Wall Integrity Signaling Pathways and Membrane Lipid Biosynthesis in Fungi: Perspectives for Aspergillus fumigatus
Published in Current protein & peptide science (01-01-2020)“…The cell wall (CW) and plasma membrane are fundamental structures that define cell shape and support different cellular functions. In pathogenic fungi, such as…”
Get more information
Journal Article -
18
Trans-chalcone activity against Trichophyton rubrum relies on an interplay between signaling pathways related to cell wall integrity and fatty acid metabolism
Published in BMC genomics (22-05-2019)“…Trichophyton rubrum is the main etiological agent of skin and nail infections worldwide. Because of its keratinolytic activity and anthropophilic nature,…”
Get full text
Journal Article -
19
High-Intensity Interval Training Does Not Change Vaspin and Omentin and Does Not Reduce Visceral Adipose Tissue in Obese Rats
Published in Frontiers in physiology (26-02-2021)“…This study aimed to determine the expression of omentin and vaspin, inflammatory markers, body composition, and lipid profile in diet-induced obese rats and…”
Get full text
Journal Article -
20
Aspergillus fumigatus MADS-Box Transcription Factor rlmA Is Required for Regulation of the Cell Wall Integrity and Virulence
Published in G3 : genes - genomes - genetics (01-09-2016)“…The Cell Wall Integrity (CWI) pathway is the primary signaling cascade that controls the de novo synthesis of the fungal cell wall, and in Saccharomyces…”
Get full text
Journal Article