Search Results - "MALAFOSSE, Alain"

Increased DNA methylation status of the serotonin receptor 5HTR1A gene promoter in schizophrenia and bipolar disorder by Carrard, Anthony, Salzmann, Annick, Malafosse, Alain, Karege, Félicien

“…Abstract Background Epigenetic changes may play a role in the etiology of psychotic diseases. It has been demonstrated that the serotonin receptor, 5HTR1A, is…”
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Contribution of Common Genetic Variants to Antidepressant Response by Tansey, Katherine E, Guipponi, Michel, Hu, Xiaolan, Domenici, Enrico, Lewis, Glyn, Malafosse, Alain, Wendland, Jens R, Lewis, Cathryn M, McGuffin, Peter, Uher, Rudolf

“…Background Pharmacogenetic studies aiming to personalize the treatment of depression are based on the assumption that response to antidepressants is a…”
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Genome-wide copy number variation in epilepsy: novel susceptibility loci in idiopathic generalized and focal epilepsies by Mefford, Heather C, Muhle, Hiltrud, Ostertag, Philipp, von Spiczak, Sarah, Buysse, Karen, Baker, Carl, Franke, Andre, Malafosse, Alain, Genton, Pierre, Thomas, Pierre, Gurnett, Christina A, Schreiber, Stefan, Bassuk, Alexander G, Guipponi, Michel, Stephani, Ulrich, Helbig, Ingo, Eichler, Evan E

“…Epilepsy is one of the most common neurological disorders in humans with a prevalence of 1% and a lifetime incidence of 3%. Several genes have been identified…”
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Childhood maltreatment and methylation of the glucocorticoid receptor gene NR3C1 in bipolar disorder by Perroud, Nader, Dayer, Alexandre, Piguet, Camille, Nallet, Audrey, Favre, Sophie, Malafosse, Alain, Aubry, Jean-Michel

“…Early-life adversities represent risk factors for the development of bipolar affective disorder and are associated with higher severity of the disorder. This…”
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The electroencephalographic fingerprint of sleep is genetically determined: A twin study by De Gennaro, Luigi, Marzano, Cristina, Fratello, Fabiana, Moroni, Fabio, Pellicciari, Maria Concetta, Ferlazzo, Fabio, Costa, Stefania, Couyoumdjian, Alessandro, Curcio, Giuseppe, Sforza, Emilia, Malafosse, Alain, Finelli, Luca A., Pasqualetti, Patrizio, Ferrara, Michele, Bertini, Mario, Rossini, Paolo Maria

“…Humans have an individual profile of the electroencephalographic power spectra at the 8 to 16Hz frequency during non–rapid eye movement sleep that is stable…”
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Impaired Decision Making in Suicide Attempters by Jollant, Fabrice, Bellivier, Frank, Leboyer, Marion, Astruc, Bernard, Torres, Stéphane, Verdier, Régis, Castelnau, Didier, Malafosse, Alain, Courtet, Philippe

“…OBJECTIVE: The understanding of suicidal behavior is incomplete. The stress-diathesis model suggests that a deficit in serotonergic projections to the…”
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Somatic markers and explicit knowledge are both involved in decision-making by Guillaume, Sébastien, Jollant, Fabrice, Jaussent, Isabelle, Lawrence, Natalia, Malafosse, Alain, Courtet, Philippe

“…In 1994, it was proposed that decision-making requires emotion-related signals, known as somatic markers. In contrast, some authors argued that conscious…”
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HPA axis genes may modulate the effect of childhood adversities on decision-making in suicide attempters by Guillaume, Sebastien, Perroud, Nader, Jollant, Fabrice, Jaussent, Isabelle, Olié, Emilie, Malafosse, Alain, Courtet, Philippe

“…Abstract Decision-making impairment is found in several neuropsychiatric disorders, including suicidal behavior, and has been shown to be modulated by genes…”
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Clinical and genetic correlates of suicidal ideation during antidepressant treatment in a depressed outpatient sample by Perroud, Nader, Bondolfi, Guido, Uher, Rudolf, Gex-Fabry, Marianne, Aubry, Jean-Michel, Bertschy, Gilles, Malafosse, Alain, Kosel, Markus

“…This study investigated clinical and genetic predictors of increasing suicidal ideation during antidepressant treatment. A total of 131 depressed outpatients…”
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Alterations in phosphatidylinositol 3-kinase activity and PTEN phosphatase in the prefrontal cortex of depressed suicide victims by Karege, Félicien, Perroud, Nader, Burkhardt, Sandra, Fernandez, Rafael, Ballmann, Eladia, La Harpe, Romano, Malafosse, Alain

“…Recent studies have reported alterations in protein kinase B (PKB)/Akt and in its downstream target, glycogen synthase kinase 3β, in depression and suicide…”
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The influence of four serotonin-related genes on decision-making in suicide attempters by Jollant, Fabrice, Buresi, Catherine, Guillaume, Sébastien, Jaussent, Isabelle, Bellivier, Frank, Leboyer, Marion, Castelnau, Didier, Malafosse, Alain, Courtet, Philippe

“…Genetic factors have been associated with the vulnerability to suicidal behavior. We previously reported decision‐making impairment in suicide attempters and…”
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Genetic variation in EEG activity during sleep in inbred mice by Franken, P, Malafosse, A, Tafti, M

“…The genetic variation in spontaneous rhythmic electroencephalographic (EEG) activity was assessed by the quantitative analysis of the EEG in six inbred mice…”
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Magnetic resonance imaging correlates of first-episode psychosis in young adult male patients: combined analysis of grey and white matter by Ruef, Anne, MSc, Curtis, Logos, MD, PhD, Moy, Guenael, PhD, Bessero, Severine, MSc, Badan Bâ, Maryse, PhD, Lazeyras, François, PhD, Lövblad, Karl-Olof, MD, Haller, Sven, MD, MSc, Malafosse, Alain, MD, PhD, Giannakopoulos, Panteleimon, MD, Merlo, Marco, MD

“…Background Several patterns of grey and white matter changes have been separately described in young adults with first-episode psychosis. Concomitant…”
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Functional variant in complement C3 gene promoter and genetic susceptibility to temporal lobe epilepsy and febrile seizures by Jamali, Sarah, Salzmann, Annick, Perroud, Nader, Ponsole-Lenfant, Magali, Cillario, Jennifer, Roll, Patrice, Roeckel-Trevisiol, Nathalie, Crespel, Ariel, Balzar, Jorg, Schlachter, Kurt, Gruber-Sedlmayr, Ursula, Pataraia, Ekaterina, Baumgartner, Christoph, Zimprich, Alexander, Zimprich, Fritz, Malafosse, Alain, Szepetowski, Pierre

“…Human mesial temporal lobe epilepsies (MTLE) represent the most frequent form of partial epilepsies and are frequently preceded by febrile seizures (FS) in…”
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Reproductive Technologies and Genomic Selection in Cattle by Heyman, Yvan, Amigues, Yves, Tissier, Michel, Ponsart, Claire, Humblot, Patrice, Malafosse, Alain, Guyader-Joly, Catherine, Gonzalez, Cyril, Le Bourhis, Daniel, Fritz, Sebastien, Colleau, Jean Jacques

“…The recent development of genomic selection induces dramatic changes in the way genetic selection schemes are to be conducted. This review describes the new…”
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Dodecamer repeat expansion in cystatin B gene in progressive myoclonus epilepsy by Lalioti, Maria D, Scott, Hamish S, Buresi, Catherine, Rossier, Colette, Bottani, Armand, Morris, Michael A, Malafosse, Alain, Antonarakis, Stylianos E

“…Progressive myoclonus epilepsy of the Unverricht-Lundborg type (EPM1; MIM 254800) is an autosomal recessive disorder with onset between 6 and 13 years followed…”
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Genetics of Temporal Lobe Epilepsy: A Review by Salzmann, Annick, Malafosse, Alain

“…Temporal lobe epilepsy (TLE) is usually regarded as a polygenic and complex disorder. To understand its genetic component, numerous linkage analyses of…”
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European collaborative study of early-onset bipolar disorder: Evidence for genetic heterogeneity on 2q14 according to age at onset by Mathieu, Flavie, Dizier, Marie-Hélène, Etain, Bruno, Jamain, Stéphane, Rietschel, Marcella, Maier, Wolfgang, Albus, Margot, McKeon, Patrick, Roche, Siobhan, Blackwood, Douglas, Muir, Walter J., Henry, Chantal, Malafosse, Alain, Preisig, Martin, Ferrero, François, Cichon, Sven, Schumacher, Johannes, Ohlraun, Stephanie, Propping, Peter, Abou Jamra, Rami, Schulze, Thomas G., Zelenica, Diana, Charon, Céline, Marusic, Andrej, Dernovsek, Mojca C., Gurling, Hugh, Nöthen, Markus, Lathrop, Mark, Leboyer, Marion, Bellivier, Frank

“…Bipolar disorder has a genetic component, but the mode of inheritance remains unclear. A previous genome scan conducted in 70 European families led to detect…”
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A Novel Protein Tyrosine Phosphatase Gene Is Mutated in Progressive Myoclonus Epilepsy of the Lafora Type (EPM2) by Serratosa, José M., Gómez-Garre, Pilar, Gallardo, Ma Esther, Anta, Berta, de Bernabé, Daniel Beltrán-Valero, Lindhout, Dick, Augustijn, Paul B., Tassinari, Carlo A., Michelucci, Roberto, Malafosse, Alain, Topcu, Meral, Grid, Djamel, Dravet, Charlotte, Berkovic, Samuel F., de Córdoba, Santiago Rodríguez

“…Progressive myoclonus epilepsy of the Lafora type or Lafora disease (EPM2; McKusick no. 254780) is an autosomal recessive disorder characterized by epilepsy,…”
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Candidate genes for temporal lobe epilepsy: a replication study by Salzmann, Annick, Perroud, Nader, Crespel, Arielle, Lambercy, Carmen, Malafosse, Alain

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