Search Results - "MAKIYAMA, TAKERU"

Cancer-Associated Venous Thromboembolism in the Real World　― From the COMMAND VTE Registry by Sakamoto, Jiro, Yamashita, Yugo, Morimoto, Takeshi, Amano, Hidewo, Takase, Toru, Hiramori, Seiichi, Kim, Kitae, Oi, Maki, Akao, Masaharu, Kobayashi, Yohei, Toyofuku, Mamoru, Izumi, Toshiaki, Tada, Tomohisa, Chen, Po-Min, Murata, Koichiro, Tsuyuki, Yoshiaki, Saga, Syunsuke, Nishimoto, Yuji, Sasa, Tomoki, Kinoshita, Minako, Togi, Kiyonori, Mabuchi, Hiroshi, Takabayashi, Kensuke, Yoshikawa, Yusuke, Shiomi, Hiroki, Kato, Takao, Makiyama, Takeru, Ono, Koh, Tamura, Toshihiro, Nakagawa, Yoshihisa, Kimura, Takeshi, on behalf of the COMMAND VTE Registry Investigators

“…Background:There is a paucity of data on the management and prognosis of cancer-associated venous thromboembolism (VTE), leading to uncertainty about optimal…”
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The genetics underlying acquired long QT syndrome: impact for genetic screening by Itoh, Hideki, Crotti, Lia, Aiba, Takeshi, Spazzolini, Carla, Denjoy, Isabelle, Fressart, Véronique, Hayashi, Kenshi, Nakajima, Tadashi, Ohno, Seiko, Makiyama, Takeru, Wu, Jie, Hasegawa, Kanae, Mastantuono, Elisa, Dagradi, Federica, Pedrazzini, Matteo, Yamagishi, Masakazu, Berthet, Myriam, Murakami, Yoshitaka, Shimizu, Wataru, Guicheney, Pascale, Schwartz, Peter J, Horie, Minoru

“…Acquired long QT syndrome (aLQTS) exhibits QT prolongation and Torsades de Pointes ventricular tachycardia triggered by drugs, hypokalaemia, or bradycardia…”
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Differential Diagnosis Between Catecholaminergic Polymorphic Ventricular Tachycardia and Long QT Syndrome Type 1　― Modified Schwartz Score by Ozawa, Junichi, Ohno, Seiko, Fujii, Yusuke, Makiyama, Takeru, Suzuki, Hiroshi, Saitoh, Akihiko, Horie, Minoru

“…Background: Catecholaminergic polymorphic ventricular tachycardia (CPVT) has been often misdiagnosed as long QT syndrome (LQTS) type 1 (LQT1), which…”
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An NGS-based genotyping in LQTS; minor genes are no longer minor by Ohno, Seiko, Ozawa, Junichi, Fukuyama, Megumi, Makiyama, Takeru, Horie, Minoru

“…Mutations in KCNQ1, KCNH2, and SCN5A are the major cause of long QT syndrome (LQTS). More than 90% of the genotyped patients have been reported to carry…”
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Ultrastructural Maturation of Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes in a Long-Term Culture by Kamakura, Tsukasa, Makiyama, Takeru, Sasaki, Kenichi, Yoshida, Yoshinori, Wuriyanghai, Yimin, Chen, Jiarong, Hattori, Tetsuhisa, Ohno, Seiko, Kita, Toru, Horie, Minoru, Yamanaka, Shinya, Kimura, Takeshi

“…Background: In the short- to mid-term, cardiomyocytes generated from human-induced pluripotent stem cells (hiPSC-CMs) have been reported to be less mature than…”
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Anticoagulation Therapy for Venous Thromboembolism in the Real World　― From the COMMAND VTE Registry by Yamashita, Yugo, Morimoto, Takeshi, Amano, Hidewo, Takase, Toru, Hiramori, Seiichi, Kim, Kitae, Konishi, Takashi, Akao, Masaharu, Kobayashi, Yohei, Inoue, Takeshi, Oi, Maki, Izumi, Toshiaki, Takahashi, Kotaro, Tada, Tomohisa, Chen, Po-Min, Murata, Koichiro, Tsuyuki, Yoshiaki, Sakai, Hiroshi, Saga, Syunsuke, Sasa, Tomoki, Sakamoto, Jiro, Yamada, Chinatsu, Kinoshita, Minako, Togi, Kiyonori, Ikeda, Tomoyuki, Ishii, Katsuhisa, Kaneda, Kazuhisa, Mabuchi, Hiroshi, Otani, Hideo, Takabayashi, Kensuke, Takahashi, Mamoru, Shiomi, Hiroki, Makiyama, Takeru, Ono, Koh, Kimura, Takeshi, on behalf of COMMAND VTE Registry Investigators

“…Background:Venous thromboembolism (VTE) has a long-term risk of recurrence, which can be prevented by anticoagulation therapy.Methods and Results:The COMMAND…”
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Risk Factors for Major Bleeding During Anticoagulation Therapy in Cancer-Associated Venous Thromboembolism　― From the COMMAND VTE Registry by Nishimoto, Yuji, Yamashita, Yugo, Kim, Kitae, Morimoto, Takeshi, Saga, Syunsuke, Amano, Hidewo, Takase, Toru, Hiramori, Seiichi, Oi, Maki, Akao, Masaharu, Kobayashi, Yohei, Toyofuku, Mamoru, Izumi, Toshiaki, Tada, Tomohisa, Chen, Po-Min, Murata, Koichiro, Tsuyuki, Yoshiaki, Sasa, Tomoki, Sakamoto, Jiro, Kinoshita, Minako, Togi, Kiyonori, Mabuchi, Hiroshi, Takabayashi, Kensuke, Yoshikawa, Yusuke, Shiomi, Hiroki, Kato, Takao, Makiyama, Takeru, Ono, Koh, Sato, Yukihito, Kimura, Takeshi, on behalf of the COMMAND VTE Registry Investigators

“…Background:Patients with cancer-associated venous thromboembolism (VTE) are at high risk for recurrent VTE and are recommended to receive prolonged…”
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A de novo gain-of-function KCND3 mutation in early repolarization syndrome by Takayama, Koichiro, Ohno, Seiko, Ding, Wei-Guang, Ashihara, Takashi, Fukumoto, Daisuke, Wada, Yuko, Makiyama, Takeru, Kise, Hiroaki, Hoshiai, Minako, Matsuura, Hiroshi, Horie, Minoru

“…Early repolarization syndrome (ERS) is characterized by J-point elevation on electrocardiograms and ventricular fibrillation (VF). Early repolarization arises…”
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Asymptomatic Lower Extremity Deep Vein Thrombosis　― Clinical Characteristics, Management Strategies, and Long-Term Outcomes by Yamashita, Yugo, Shiomi, Hiroki, Morimoto, Takeshi, Yoneda, Tomoya, Yamada, Chinatsu, Makiyama, Takeru, Kato, Takao, Saito, Naritatsu, Shizuta, Satoshi, Ono, Koh, Kimura, Takeshi

“…Background:The prognosis of asymptomatic deep vein thrombosis (DVT) is uncertain and there is no consensus on the necessity of detection and treatment.Methods…”
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Asian patients versus non-Asian patients in the efficacy and safety of direct oral anticoagulants relative to vitamin K antagonist for venous thromboembolism: A systemic review and meta-analysis by Yamashita, Yugo, Morimoto, Takeshi, Toyota, Toshiaki, Shiomi, Hiroki, Makiyama, Takeru, Ono, Koh, Kimura, Takeshi

“…The standard for treatment and secondary prevention of venous thromboembolism (VTE) has been vitamin K antagonist (VKA), which might be associated with a…”
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Clinical Impact of Left Ventricular Outflow Tract Obstruction in Takotsubo Cardiomyopathy by Kawaji, Tetsuma, Shiomi, Hiroki, Morimoto, Takeshi, Tazaki, Junichi, Imai, Masao, Saito, Naritatsu, Makiyama, Takeru, Shizuta, Satoshi, Ono, Koh, Kimura, Takeshi

“…Background:A hyperdynamic state of the basal left ventricle sometimes results in obstruction of the left ventricular outflow tract (LVOT). However, the…”
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High Prevalence of Late-Appearing T-Wave in Patients With Long QT Syndrome Type 8 by Fukuyama, Megumi, Ohno, Seiko, Ozawa, Junichi, Kato, Koichi, Makiyama, Takeru, Nakagawa, Yoshihisa, Horie, Minoru

“…Background:Long QT syndrome type 8 (LQT8) is a rare genotype of long QT syndrome. Late-appearing T-waves (LaT) are often documented in patients with LQT8, as…”
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Loss-of-function mutations in cardiac ryanodine receptor channel cause various types of arrhythmias including long QT syndrome by Hirose, Sayako, Murayama, Takashi, Tetsuo, Naoyuki, Hoshiai, Minako, Kise, Hiroaki, Yoshinaga, Masao, Aoki, Hisaaki, Fukuyama, Megumi, Wuriyanghai, Yimin, Wada, Yuko, Kato, Koichi, Makiyama, Takeru, Kimura, Takeshi, Sakurai, Takashi, Horie, Minoru, Kurebayashi, Nagomi, Ohno, Seiko

“…Abstract Aims Gain-of-function mutations in RYR2, encoding the cardiac ryanodine receptor channel (RyR2), cause catecholaminergic polymorphic ventricular…”
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D85N, a KCNE1 Polymorphism, Is a Disease-Causing Gene Variant in Long QT Syndrome by Nishio, Yukiko, MD, Makiyama, Takeru, MD, PhD, Itoh, Hideki, MD, PhD, Sakaguchi, Tomoko, MD, PhD, Ohno, Seiko, MD, PhD, Gong, Yin-Zhi, MD, PhD, Yamamoto, Satoshi, MD, Ozawa, Tomoya, MD, PhD, Ding, Wei-Guang, MD, PhD, Toyoda, Futoshi, PhD, Kawamura, Mihoko, MD, Akao, Masaharu, MD, PhD, Matsuura, Hiroshi, MD, PhD, Kimura, Takeshi, MD, PhD, Kita, Toru, MD, PhD, Horie, Minoru, MD, PhD

“…Objectives This study aims to address whether D85N, a KCNE1 polymorphism, is a gene variant that causes long QT syndrome (LQTS) phenotype. Background KCNE1…”
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Patient-Specific Human Induced Pluripotent Stem Cell Model Assessed with Electrical Pacing Validates S107 as a Potential Therapeutic Agent for Catecholaminergic Polymorphic Ventricular Tachycardia by Sasaki, Kenichi, Makiyama, Takeru, Yoshida, Yoshinori, Wuriyanghai, Yimin, Kamakura, Tsukasa, Nishiuchi, Suguru, Hayano, Mamoru, Harita, Takeshi, Yamamoto, Yuta, Kohjitani, Hirohiko, Hirose, Sayako, Chen, Jiarong, Kawamura, Mihoko, Ohno, Seiko, Itoh, Hideki, Takeuchi, Ayako, Matsuoka, Satoshi, Miura, Masaru, Sumitomo, Naokata, Horie, Minoru, Yamanaka, Shinya, Kimura, Takeshi

“…Human induced pluripotent stem cells (hiPSCs) offer a unique opportunity for disease modeling. However, it is not invariably successful to recapitulate the…”
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Clinical Manifestations and Long-Term Mortality in Lamin A/C Mutation Carriers From a Japanese Multicenter Registry by Nakajima, Kenzaburo, Aiba, Takeshi, Makiyama, Takeru, Nishiuchi, Suguru, Ohno, Seiko, Kato, Koichi, Yamamoto, Yuta, Doi, Takahiro, Shizuta, Satoshi, Onoue, Kenji, Yagihara, Nobue, Ishikawa, Taisuke, Watanabe, Ichiro, Kawakami, Hiroshi, Oginosawa, Yasushi, Murakoshi, Nobuyuki, Nogami, Akihiko, Aonuma, Kazutaka, Saito, Yoshihiko, Kimura, Takeshi, Yasuda, Satoshi, Makita, Naomasa, Shimizu, Wataru, Horie, Minoru, Kusano, Kengo

“…Background: Mutation in the lamin A/C gene (LMNA) is associated with several cardiac phenotypes, such as cardiac conduction disorders (CCD), atrial arrhythmia…”
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Increased CaV1.2 late current by a CACNA1C p.R412M variant causes an atypical Timothy syndrome without syndactyly by Ozawa, Junichi, Ohno, Seiko, Melgari, Dario, Wang, Qi, Fukuyama, Megumi, Toyoda, Futoshi, Makiyama, Takeru, Yoshinaga, Masao, Suzuki, Hiroshi, Saitoh, Akihiko, Ai, Tomohiko, Horie, Minoru

“…Timothy syndrome (TS) is a rare pleiotropic disorder associated with long QT syndrome, syndactyly, dysmorphic features, and neurological symptoms. Several…”
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Novel SCN3B Mutation Associated With Brugada Syndrome Affects Intracellular Trafficking and Function of Nav1.5 by Ishikawa, Taisuke, Takahashi, Naohiko, Ohno, Seiko, Sakurada, Harumizu, Nakamura, Kazufumi, On, Young Keun, Park, Jeong Euy, Makiyama, Takeru, Horie, Minoru, Arimura, Takuro, Makita, Naomasa, Kimura, Akinori

“…Background: Brugada syndrome (BrS) is characterized by specific alterations on ECG in the right precordial leads and associated with ventricular arrhythmia…”
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Telethonin variants found in Brugada syndrome, J‐wave pattern ECG, and ARVC reduce peak Nav1.5 currents in HEK‐293 cells by Turker, Isik, Makiyama, Takeru, Ueyama, Takeshi, Shimizu, Akihiko, Yamakawa, Masaru, Chen, Peng‐Sheng, Vatta, Matteo, Horie, Minoru, Ai, Tomohiko

“…Background Telethonin (TCAP) is a Z‐disk protein that maintains cytoskeletal integrity and various signaling pathways in cardiomyocytes. TCAP is shown to…”
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Gradient-based parameter optimization method to determine membrane ionic current composition in human induced pluripotent stem cell-derived cardiomyocytes by Kohjitani, Hirohiko, Koda, Shigeya, Himeno, Yukiko, Makiyama, Takeru, Yamamoto, Yuta, Yoshinaga, Daisuke, Wuriyanghai, Yimin, Kashiwa, Asami, Toyoda, Futoshi, Zhang, Yixin, Amano, Akira, Noma, Akinori, Kimura, Takeshi

“…Premature cardiac myocytes derived from human induced pluripotent stem cells (hiPSC-CMs) show heterogeneous action potentials (APs), probably due to different…”
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