Search Results - "MAKINO, SHINYA"

Animal Models of Cushing's Syndrome by Nishiyama, Mitsuru, Iwasaki, Yasumasa, Makino, Shinya

“…Abstract Endogenous Cushing's syndrome is characterized by unique clinical features and comorbidities, and progress in the analysis of its genetic pathogenesis…”
Get full text

Editorial: Effects of midday naps on glycemic control of diabetic patients by Makino, Shinya, Al-Abri, Mohammed A

Get full text

Relationships between time in range, glycemic variability including hypoglycemia and types of diabetes therapy in Japanese patients with type 2 diabetes mellitus: Hyogo Diabetes Hypoglycemia Cognition Complications study by Kuroda, Norihiro, Kusunoki, Yoshiki, Osugi, Keiko, Ohigashi, Mana, Azuma, Daisuke, Ikeda, Hiroki, Makino, Shinya, Otsuka, Akihito, Tamada, Daisuke, Watanabe, Nobuaki, Washio, Kahori, Tsunoda, Taku, Matsuo, Toshihiro, Konishi, Kosuke, Katsuno, Tomoyuki, Koyama, Hidenori

“…Aims/Introduction Continuous glucose monitoring (CGM) metrics, such as times in range (TIR) and time below range, have been shown to be useful as clinical…”
Get full text

Novel splice site variant of TMEM38B in osteogenesis imperfecta type XIV by Kodama, Yoshihiko, Meiri, Satoru, Asada, Tomoko, Matsuyama, Misayo, Makino, Shinya, Iwai, Minayo, Yamaguchi, Masatoshi, Moritake, Hiroshi

“…Osteogenesis imperfecta (OI) is a rare genetic disorder characterized by brittle bones. In this case report, we describe a patient who suffered from OI type…”
Get full text

Regulation of Glucocorticoid Receptor Transcription and Nuclear Translocation during Single and Repeated Immobilization Stress by Noguchi, Tohru, Makino, Shinya, Matsumoto, Reiko, Nakayama, Shuichi, Nishiyama, Mitsuru, Terada, Yoshio, Hashimoto, Kozo

“…We have previously reported reduced glucocorticoid receptor (GR) mRNA levels in the hippocampus and hypothalamic paraventricular nucleus (PVN) during repeated…”
Get full text

Multiple feedback mechanisms activating corticotropin-releasing hormone system in the brain during stress by Makino, Shinya, Hashimoto, Kozo, Gold, Philip W

“…Stress-associated disorders such as melancholic depression are characterized by persistent hypothalamic–pituitary–adrenocortical (HPA) axis activation and…”
Get full text

Strain-induced crystallization of peroxide-crosslinked natural rubber by Ikeda, Yuko, Yasuda, Yoritaka, Makino, Shinya, Yamamoto, Shinya, Tosaka, Masatoshi, Senoo, Kazunobu, Kohjiya, Shinzo

“…Effect of network-chain density ( ν) on the strain-induced crystallization of peroxide-crosslinked natural rubber was studied by fast time-resolved synchrotron…”
Get full text

Obstructive sleep apnoea syndrome, plasma adiponectin levels, and insulin resistance by Makino, Shinya, Handa, Hiroshi, Suzukawa, Koji, Fujiwara, Masayoshi, Nakamura, Masaharu, Muraoka, Shogo, Takasago, Ikumi, Tanaka, Yasushi, Hashimoto, Kozo, Sugimoto, Tamotsu

“…Summary Objective  To investigate whether sleep‐disordered breathing and/or plasma adiponectin levels are associated with insulin resistance independent of…”
Get full text

Association between brain imaging biomarkers and continuous glucose monitoring-derived glycemic control indices in Japanese patients with type 2 diabetes mellitus by Inoue, Chikako, Kusunoki, Yoshiki, Ohigashi, Mana, Osugi, Keiko, Kitajima, Kazuhiro, Takagi, Ayako, Inoue, Maki, Yagi, Chisako, Tsunoda, Taku, Kakutani, Miki, Kadoya, Manabu, Konishi, Kosuke, Katsuno, Tomoyuki, Koyama, Hidenori, Kusunoki, Yoshiki, Osugi, Keiko, Ohigashi, Mana, Inoue, Chikako, Inoue, Maki, Takagi, Ayako, Yagi, Chisako, Morimoto, Akiko, Tsunoda, Taku, Kakutani, Miki, Kanzaki, Akinori, Kadoya, Manabu, Konishi, Kosuke, Shoji, Takuhito, Katsuno, Tomoyuki, Koyama, Hidenori, Konya, Hiroyuki, Matsuo, Toshihiro, Ifuku, Hideki, Azuma, Daisuke, Fukui, Takeshi, Hayashi, Isao, Katayama, Satoru, Kanyama, Masataka, Usami, Masaru, Ikeda, Hiroki, Inagaki, Tadahiro, Hamaguchi, Tomoya, Otsuka, Akihito, Kurebayashi, Shogo, Kusunoki, Kenji, Kubota, Minoru, Sasaki, Takeharu, Hirose, Sachie, Matsutani, Satoshi, Makino, Shinya, Kitamura, Tetsuhiro, Tamada, Daisuke, Taniguchi, Hidenori, Watanabe, Nobuaki, Namba, Mitsuyoshi

“…IntroductionAlthough type 2 diabetes mellitus (T2DM) is associated with alterations in brain structure, the relationship between glycemic control indices and…”
Get full text

Application of Fenton reaction for nanomolar determination of hydrogen peroxide in seawater by Olasehinde, Emmanuel F., Makino, Shinya, Kondo, Hiroaki, Takeda, Kazuhiko, Sakugawa, Hiroshi

“…A simple and sensitive method for the determination of nanomolar levels of hydrogen peroxide (H 2O 2) in seawater has been developed and validated. This method…”
Get full text

Corticotropin-releasing hormone (CRH) transgenic mice display hyperphagia with increased Agouti-related protein mRNA in the hypothalamic arcuate nucleus by Nakayama, Shuichi, Nishiyama, Mitsuru, Iwasaki, Yasumasa, Shinahara, Masayuki, Okada, Yasushi, Tsuda, Masayuki, Okazaki, Mizuho, Tsugita, Makoto, Taguchi, Takafumi, Makino, Shinya, Stenzel-Poore, Mary P, Hashimoto, Kozo, Terada, Yoshio

“…Although glucocorticoid-induced hyperphagia is observed in the patients with glucocorticoid treatment or Cushing’s syndrome, its molecular mechanism is not…”
Get full text

Corticosterone effects on corticotropin-releasing hormone mRNA in the central nucleus of the amygdala and the parvocellular region of the paraventricular nucleus of the hypothalamus by Makino, S, Gold, P W, Schulkin, J

“…Using in situ hybridization histochemistry, we report differential expression of corticotropin-releasing hormone (CRH) mRNA in the central nucleus of the…”
Get more information

A Case of Abrupt Onset Autoimmune Type 1 Diabetes Mimicking Fulminant Type 1 Diabetes by MAKINO, Shinya, HAMADA, Sumio, IWATA, Masanobu, FUJIWARA, Masayoshi

“…A 63-year-old male was admitted to our hospital with diabetic ketoacidosis. He had flu-like symptoms 10 days before admission and developed thirst, polyuria…”
Get full text

Regulatory role of glucocorticoids and glucocorticoid receptor mRNA levels on tyrosine hydroxylase gene expression in the locus coeruleus during repeated immobilization stress by Makino, Shinya, Smith, Mark A, Gold, Philip W

“…Sustained responsiveness of the hypothalamic–pituitary–adrenal (HPA) axis during chronic or repeated stress is associated with continuous activation of…”
Get full text

Effects of stress on neurotrophic factor expression in the rat brain by Smith, M A, Makino, S, Kvetnanský, R, Post, R M

“…Changes in neurotrophic factor expression in the brain are part of the stress response. Decreased BDNF may contribute to hippocampal damage that occurs during…”
Get more information

A Case of Abrupt Onset Autoimmune Type 1 Diabetes Mimicking Fulminant Type 1 Diabetes by SHINYA MAKINO, SUMIO HAMADA, MASANOBU IWATA, MASAYOSHI FUJIWARA

“…A 63-year-old male was admitted to our hospital with diabetic ketoacidosis. He had flu-like symptoms 10 days before admission and developed thirst, polyuria…”
Get full text

CRH mRNA expression in the hypothalamic paraventricular nucleus is inhibited despite the activation of the hypothalamo-pituitary-adrenal axis during starvation by Nishiyama, Mitsuru, Makino, Shinya, Iwasaki, Yasumasa, Tanaka, Yasushi, Nazarloo, Hossein Pournajafi, Kaneda, Tadafumi, Asaba, Koichi, Hashimoto, Kozo

“…Abstract Corticotropin-releasing hormone (CRH) is one of the anorexigenic neuropeptides, and indeed the expression of hypothalamic CRH is known to be inhibited…”
Get full text

Physiological Roles of Corticotropin-Releasing Hormone Receptor Type 2 by HASHIMOTO, KOZO, MAKINO, SHINYA, ASABA, KOICHI, NISHIYAMA, MITSURU

“…Recent investigations of the physiological roles of CRH-R2 are reviewed and summarized in Fig. 5. VMH CRH-R2 is more important than CRH-R1 in mediating…”
Get full text

Lymphocytic Adenohypophysitis and Lymphocytic Infundibuloneurohypophysitis by HASHIMOTO, KOZO, TAKAO, TOSIHIRO, MAKINO, SHINYA

“…One hundred and twenty-four cases of lymphocytic adenohypophysitis have been reported since 1962. Nearly 60% of the cases in women involved onset of the…”
Get full text

Effect of stress and adrenalectomy on urocortin II mRNA expression in the hypothalamic paraventricular nucleus of the rat by Tanaka, Yasushi, Makino, Shinya, Noguchi, Tohru, Tamura, Kanae, Kaneda, Tadafumi, Hashimoto, Kozo

“…Urocortin II (Ucn II) is a novel corticotropin-releasing hormone (CRH)-related peptide discovered as a selective agonist for type-2 CRH receptor. In the rat or…”
Get more information