Search Results - "MAJANO, Pedro L"
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Carcinoma-associated fibroblasts derive from mesothelial cells via mesothelial-to-mesenchymal transition in peritoneal metastasis
Published in The Journal of pathology (01-12-2013)“…Peritoneal dissemination is a frequent metastatic route for cancers of the ovary and gastrointestinal tract. Tumour cells metastasize by attaching to and…”
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Blocking TGF-β1 Protects the Peritoneal Membrane from Dialysate-Induced Damage
Published in Journal of the American Society of Nephrology (01-09-2011)“…During peritoneal dialysis (PD), mesothelial cells undergo mesothelial-to-mesenchymal transition (MMT), a process associated with peritoneal-membrane…”
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Clathrin mediates infectious hepatitis C virus particle egress
Published in Journal of virology (01-04-2015)“…Although it is well established that hepatitis C virus (HCV) entry into hepatocytes depends on clathrin-mediated endocytosis, the possible roles of clathrin in…”
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Functional relevance of the switch of VEGF receptors/co-receptors during peritoneal dialysis-induced mesothelial to mesenchymal transition
Published in PloS one (09-04-2013)“…Vascular endothelial growth factor (VEGF) is up-regulated during mesothelial to mesenchymal transition (MMT) and has been associated with peritoneal membrane…”
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The Tight Junction-Associated Protein Occludin Is Required for a Postbinding Step in Hepatitis C Virus Entry and Infection
Published in Journal of Virology (15-08-2009)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Hepatitis C virus envelope components alter localization of hepatocyte tight junction–associated proteins and promote occludin retention in the endoplasmic reticulum
Published in Hepatology (Baltimore, Md.) (01-10-2008)“…Hepatocyte tight junctions (TJ) play key roles in characteristic liver functions, including bile formation and secretion. Infection by hepatitis C virus (HCV)…”
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Apicobasal Polarity Controls Lymphocyte Adhesion to Hepatic Epithelial Cells
Published in Cell reports (Cambridge) (25-09-2014)“…Loss of apicobasal polarity is a hallmark of epithelial pathologies. Leukocyte infiltration and crosstalk with dysfunctional epithelial barriers are crucial…”
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Expression of pituitary tumor–transforming gene 1 (PTTG1)/securin in hepatitis B virus (HBV)‐associated liver diseases: Evidence for an HBV X protein–mediated inhibition of PTTG1 ubiquitination and degradation
Published in Hepatology (Baltimore, Md.) (01-03-2010)“…Chronic infection with hepatitis B virus (HBV) is strongly associated with hepatocellular carcinoma (HCC), and the viral HBx protein plays a crucial role in…”
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Interplay among cellular polarization,lipoprotein metabolism and hepatitis C virus entry
Published in World journal of gastroenterology : WJG (14-06-2011)“…Hepatitis C virus (HCV) infects more than three million new individuals worldwide each year. In a high percent age of patients, acute infections become…”
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Modulation of PI3K-LXRα-dependent lipogenesis mediated by oxidative/nitrosative stress contributes to inhibition of HCV replication by quercetin
Published in Laboratory investigation (01-03-2014)“…There is experimental evidence that some antioxidant flavonoids show therapeutic potential in the treatment of hepatitis C through inhibition of hepatitis C…”
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Polyanionic carbosilane dendrimers prevent hepatitis C virus infection in cell culture
Published in Nanomedicine (01-01-2017)“…Abstract Hepatitis C virus (HCV) infection is a major biomedical problem worldwide. Although new direct antiviral agents (DAAs) have been developed for the…”
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Apolipoprotein E, but Not Apolipoprotein B, Is Essential for Efficient Cell-to-Cell Transmission of Hepatitis C Virus
Published in Journal of virology (01-10-2015)“…Hepatitis C virus (HCV) infects hepatocytes through two different routes: (i) cell-free particle diffusion followed by engagement with specific cellular…”
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Hepatitis C virus NS5A and core proteins induce oxidative stress-mediated calcium signalling alterations in hepatocytes
Published in Journal of hepatology (01-05-2009)“…Background/Aims The hepatitis C virus (HCV) structural core and non-structural NS5A proteins induce in liver cells a series of intracellular events, including…”
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Effect of the hepatitis B virus HBx protein on integrin-mediated adhesion to and migration on extracellular matrix
Published in Journal of hepatology (01-03-2001)“…The hepatitis B virus HBx protein is associated with the development of hepatocellular carcinoma (HCC). However, its possible contribution to tumor spreading…”
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Matrigel-embedded 3D culture of Huh-7 cells as a hepatocyte-like polarized system to study hepatitis C virus cycle
Published in Virology (New York, N.Y.) (30-03-2012)“…Abstract Hepatocytes are highly polarized cells where intercellular junctions, including tight junctions (TJs), determine the polarity. Recently, the…”
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The hepatitis B virus X protein induces paracrine activation of human hepatic stellate cells
Published in Hepatology (Baltimore, Md.) (01-06-2008)“…Chronic hepatitis B virus (HBV) infection is a major cause of liver fibrosis, eventually leading to cirrhosis and hepatocellular carcinoma. Although the…”
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Increased expression of T cell chemokines and their receptors in chronic hepatitis C: relationship with the histological activity of liver disease
Published in The American journal of gastroenterology (01-11-2002)“…Although chemokines seem to be important in certain inflammatory disorders, little is known about the role of these proteins in chronic hepatitis C. Expression…”
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Role of tight junctions in hepatitis C virus infection
Published in Revista española de enfermedades digestivas (01-05-2012)Get full text
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Intrahepatic accumulation of nitrotyrosine in chronic viral hepatitis is associated with histological severity of liver disease
Published in Journal of hepatology (01-02-2000)“…Background/Aims: The toxicity of nitric oxide is thought to be engendered, at least in part, by its reaction with superoxide yielding peroxynitrite, a potent…”
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