Search Results - "MAITRA, Ratan K"

The Toll-Like Receptor 5 Agonist Entolimod Mitigates Lethal Acute Radiation Syndrome in Non-Human Primates by Krivokrysenko, Vadim I, Toshkov, Ilia A, Gleiberman, Anatoli S, Krasnov, Peter, Shyshynova, Inna, Bespalov, Ivan, Maitra, Ratan K, Narizhneva, Natalya V, Singh, Vijay K, Whitnall, Mark H, Purmal, Andrei A, Shakhov, Alexander N, Gudkov, Andrei V, Feinstein, Elena

“…There are currently no approved medical radiation countermeasures (MRC) to reduce the lethality of high-dose total body ionizing irradiation expected in…”
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Regulated Release of L13a from the 60S Ribosomal Subunit as A Mechanism of Transcript-Specific Translational Control by Mazumder, Barsanjit, Sampath, Prabha, Seshadri, Vasudevan, Maitra, Ratan K, DiCorleto, Paul E, Fox, Paul L

“…Transcript-specific translational control is generally directed by binding of trans-acting proteins to structural elements in the untranslated region (UTR) of…”
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Inhibition of STAT 1 Phosphorylation by Human Parainfluenza Virus Type 3 C Protein by MALUR, Achut G, CHATTOPADHYAY, Santanu, MAITRA, Ratan K, BANERJEE, Amiya K

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Identification of granulocyte colony-stimulating factor and interleukin-6 as candidate biomarkers of CBLB502 efficacy as a medical radiation countermeasure by Krivokrysenko, Vadim I, Shakhov, Alexander N, Singh, Vijay K, Bone, Frederick, Kononov, Yevgeniy, Shyshynova, Inna, Cheney, Alec, Maitra, Ratan K, Purmal, Andrei, Whitnall, Mark H, Gudkov, Andrei V, Feinstein, Elena

“…Given an ever-increasing risk of nuclear and radiological emergencies, there is a critical need for development of medical radiation countermeasures (MRCs)…”
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The p38 and JNK Pathways Cooperate to trans-Activate Vitamin D Receptor via c-Jun/AP-1 and Sensitize Human Breast Cancer Cells to Vitamin D3-induced Growth Inhibition by Qi, Xiaomei, Pramanik, Rocky, Wang, Jintang, Schultz, Richard M., Maitra, Ratan K., Han, Jiahuai, DeLuca, Hector F., Chen, Guan

“…The signaling connection between mitogen-activated protein kinases(MAPKs) and nuclear steroid receptors is complex and remains mostly unexplored. Here we…”
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Inhibition of vesicular stomatitis virus infection in epithelial cells by alpha interferon-induced soluble secreted proteins by Basu, Mausumi, Maitra, Ratan K, Xiang, Yan, Meng, Xiangzhi, Banerjee, Amiya K, Bose, Santanu

“…1 Department of Molecular Genetics/Virology Section, The Lerner Research Institute, The Cleveland Clinic Foundation, Cleveland, OH 44195, USA 2 Virus Core…”
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Characterization of the Solution Complex between the Interferon-induced, Double-stranded RNA-activated Protein Kinase and HIV-I Trans-activating Region RNA by Carpick, B W, Graziano, V, Schneider, D, Maitra, R K, Lee, X, Williams, B R

“…The antiviral activity of the interferon-induced, double-stranded RNA (dsRNA)-activated protein kinase (PKR) is mediated through dsRNA binding leading to PKR…”
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Regulation of Human Immunodeficiency Virus Replication by 2′,5′-Oligoadenylate-Dependent RNase L by Maitra, R K, Silverman, R H

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Prevention of Cardiac Hypertrophy and Heart Failure by Silencing of NF-κB by Gupta, Sudhiranjan, Young, David, Maitra, Ratan K., Gupta, Anasuya, Popovic, Zoran B., Yong, Sandro L., Mahajan, Anjuli, Wang, Qing, Sen, Subha

“…Activation of the nuclear factor (NF)-κB signaling pathway may be associated with the development of cardiac hypertrophy and its transition to heart failure…”
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Nuclease-Resistant Composite 2‘,5‘-Oligoadenylate−3‘,5‘-Oligonucleotides for the Targeted Destruction of RNA:  2−5A-Iso-antisense by Xiao, Wei, Li, Guiying, Player, Mark R, Maitra, Ratan K, Waller, Cornelius F, Silverman, Robert H, Torrence, Paul F

“…A new modification of 2−5A-antisense, 2−5A-iso-antisense, has been developed based on a reversal of the direction of the polarity of the antisense domain of a…”
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The nef gene from a long-term HIV type 1 nonprogressor by Premkumar, D R, Ma, X Z, Maitra, R K, Chakrabarti, B K, Salkowitz, J, Yen-Lieberman, B, Hirsch, M S, Kestler, H W

“…We examined the nef gene of HIV-1 in a long-term nonprogressor to look for evidence suggesting an attenuated virus. The nef gene was previously shown to be…”
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Correlation of Selective Modifications to a 2‘,5‘-Oligoadenylate−3‘,5‘-Deoxyribonucleotide Antisense Chimera with Affinity for the Target Nucleic Acid and with Ability To Activate RNase L by Xiao, Wei, Li, Guiying, Maitra, Ratan K, Maran, Avudaiappan, Silverman, Robert H, Torrence, Paul F

“…The use of an antisense oligonucleotide to address a specific targeted RNA sequence and subsequent localized activation of the 2-5A-dependent RNase (RNase L)…”
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The Toll-Like Receptor 5 Agonist Entolimod Mitigates Lethal Acute Radiation Syndrome in Non-Human Primates: e0135388 by Krivokrysenko, Vadim I, Toshkov, Ilia A, Gleiberman, Anatoli S, Krasnov, Peter, Shyshynova, Inna, Bespalov, Ivan, Maitra, Ratan K, Narizhneva, Natalya V, Singh, Vijay K, Whitnall, Mark H

“…There are currently no approved medical radiation countermeasures (MRC) to reduce the lethality of high-dose total body ionizing irradiation expected in…”
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Blockage of NF-κB Signaling by Selective Ablation of an mRNA Target by 2-5A Antisense Chimeras by Maran, Avudaiappan, Maitra, Ratan K., Kumar, Aseem, Dong, Beihua, Xiao, Wei, Li, Guiying, Bryan R. G. Williams, Torrence, Paul F., Silverman, Robert H.

“…Activation of 2-5A-dependent ribonuclease by 5′-phosphorylated, 2′,5′-linked oligoadenylates, known as 2-5A, is one pathway of interferon action. Unaided…”
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HIV-1 TAR RNA has an intrinsic ability to activate interferon-inducible enzymes by Maitra, R K, McMillan, N A, Desai, S, McSwiggen, J, Hovanessian, A G, Sen, G, Williams, B R, Silverman, R H

“…The TAR sequence at the 5'-termini of all HIV-1 mRNA species forms a stable structure that is responsible for both transcriptional and translational regulation…”
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The p38 and JNK pathways cooperate to trans-activate vitamin D receptor via c-Jun/AP-1 and sensitize human breast cancer cells to vitamin D(3)-induced growth inhibition by Qi, Xiaomei, Pramanik, Rocky, Wang, Jintang, Schultz, Richard M, Maitra, Ratan K, Han, Jiahuai, DeLuca, Hector F, Chen, Guan

“…The signaling connection between mitogen-activated protein kinases(MAPKs) and nuclear steroid receptors is complex and remains mostly unexplored. Here we…”
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Targeting RNA for degradation with a (2'-5')oligoadenylate-antisense chimera by TORRENCE, P. F, MAITRA, R. K, LESIAK, K, SHAHRZAD KHAMNEI, AIMIN ZHOU, SILVERMAN, R. H

“…Antisense oligonucleotides hold considerable promise both as research tools for inhibiting gene expression and as agents for the treatment of a myriad of human…”
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Prevention of cardiac hypertrophy and heart failure by silencing of NF-kappaB by Gupta, Sudhiranjan, Young, David, Maitra, Ratan K, Gupta, Anasuya, Popovic, Zoran B, Yong, Sandro L, Mahajan, Anjuli, Wang, Qing, Sen, Subha

“…Activation of the nuclear factor (NF)-kappaB signaling pathway may be associated with the development of cardiac hypertrophy and its transition to heart…”
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2′,5′-Oligoadenylate-Antisense Chimeras Cause RNase L to Selectively Degrade bcr/abl mRNA in Chronic Myelogenous Leukemia Cells by Maran, Avudaiappan, Waller, Cornelius F., Paranjape, Jayashree M., Li, Guiying, Xiao, Wei, Zhang, Kerry, Kalaycio, Matt E., Maitra, Ratan K., Lichtin, Alan E., Brugger, Wolfram, Torrence, Paul F., Silverman, Robert H.

“…We report an RNA targeting strategy, which selectively degrades bcr/abl mRNA in chronic myelogenous leukemia (CML) cells. A 2′,5′-tetraadenylate activator…”
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Catalytic Cleavage of an RNA Target by 2–5A Antisense and RNase L (∗) by Maitra, Ratan K., Li, Guiying, Xiao, Wei, Dong, Beihua, Torrence, Paul F., Silverman, Robert H.

“…2-5A antisense (2-5A-AS) molecules are chimeric oligonucleotides that cause 2-5A-dependent RNase (RNase L) to catalyze the selective cleavage of RNA in human…”
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