Search Results - "MAITI, Arup"

Asymmetric total syntheses of panaxytriol and panaxydol, potent antitumor agents from Panax ginseng by Yadav, J.S, Maiti, Arup

“…A stereoselective syntheses of panaxytriol 1 and panaxydol 2 from d-arabinose using base induced double elimination of 4,5- O-isopropylidene propargyl chloride…”
Get full text

Zapotin Prevents Mouse Skin Tumorigenesis During the Stages of Initiation and Promotion by CUENDET, Muriel, OTEHAM, Carol P, MAITI, Arup, CRAIG, Bruce A, CUSHMAN, Mark, MOON, Richard C, PEZZUTO, John M

“…Background: Zapotin, a flavonoid associated with Casimiroa edulis, was isolated as part of a program to discover natural inhibitors of carcinogenesis. Zapote…”
Get full text

Structure‐based discovery of (S)‐2‐amino‐6‐(4‐fluorobenzyl)‐5,6,11,11a‐tetrahydro‐1H‐imidazo[1′,5′:1,6]pyrido[3,4‐b]indole‐1,3(2H)‐dione as low nanomolar, orally bioavailable autotaxin inhibitor by Roy, Ashis, Sarkar, Tonmoy, Datta, Sebak, Maiti, Arup, Chakrabarti, Monali, Mondal, Trisha, Mondal, Chaitali, Banerjee, Apurba, Roy, Subhasis, Mukherjee, Soumen, Muley, Pragati, Chakraborty, Sabyasachi, Banerjee, Manish, Kundu, Mrinalkanti, Roy, Kuldeep K.

“…Inhibition of extracellular secreted enzyme autotaxin (ATX) represents an attractive strategy for the development of new therapeutics to treat various diseases…”
Get full text

Synthesis and Biological Evaluation of (±)-Abyssinone II and Its Analogues as Aromatase Inhibitors for Chemoprevention of Breast Cancer by Maiti, Arup, Cuendet, Muriel, Croy, Vicki L, Endringer, Denise C, Pezzuto, John M, Cushman, Mark

“…An efficient and economical synthesis of the naturally occurring aromatase inhibitor abyssinone II was performed. The synthesis features an optimized aromatic…”
Get full text

Synthesis of Casimiroin and Optimization of Its Quinone Reductase 2 and Aromatase Inhibitory Activities by Maiti, Arup, Reddy, P. V. Narasimha, Sturdy, Megan, Marler, Laura, Pegan, Scott D, Mesecar, Andrew D, Pezzuto, John M, Cushman, Mark

“…An efficient method has been developed to synthesize casimiroin (1), a component of the edible fruit of Casimiroa edulis, on a multigram scale in good overall…”
Get full text

Novel Pyrimidinone Derivatives Show Anticancer Activity and Induce Apoptosis: Synthesis, SAR and Putative Binding Mode by Roy, Ashis, Kundu, Mrinalkanti, Dhar, Pranab, Chakraborty, Arnish, Mukherjee, Soumen, Naskar, Jayatri, Rarhi, Chhanda, Barik, Rajib, Mondal, Susanta Kumar, Wani, Mushtaq Ahmad, Gajbhiye, Rahul, Roy, Kuldeep K., Maiti, Arup, Manna, Priyadarshi, Adhikari, Susanta

“…A series of novel bicyclic, substituted pyrimidinone compounds were designed, synthesized and characterized. In vitro anti‐proliferative activity of the…”
Get full text

Synthesis and Cancer Chemopreventive Activity of Zapotin, a Natural Product from Casimiroa edulis by Maiti, Arup, Cuendet, Muriel, Kondratyuk, Tamara, Croy, Vicki L., Pezzuto, John M., Cushman, Mark

“…An efficient method has been developed to synthesize zapotin (5,6,2‘,6‘-tetramethoxyflavone), a component of the edible fruit Casimiroa edulis, on a multigram…”
Get full text

From Dimerization, to Cycloaddition, to Atom Transfer Cyclization:  The Further Chemistry of TMM Diradicals by Maiti, Arup, Gerken, James B, Masjedizadeh, Mohammad R, Mimieux, Yvette S, Little, R. Daniel

“…We describe [a] the first examples of intramolecular cycloaddition of a TMM diyl to a remotely tethered aldehyde, [b] the effect of a Lewis acid upon the…”
Get full text

A highly efficient and practical method for the synthesis of chiral polyhydroxy diacetylenic alcohols by Yadav, J.S, Maiti, Arup

“…An efficient protocol for the synthesis of chiral polyhydroxy diacetylenic alcohols from chiral 4,5- O-isopropylidene propargyl chlorides using strong bases is…”
Get full text

Asymmetric Synthesis of (+)-allo-Quercitol and (+)-talo-Quercitol via Free Radical Cycloisomerization of an Enantiomerically Pure Alkyne-Tethered Aldehyde Derived from a Carbohydrate by YADAV, J. S., MAITI, Arup, SANKAR, A. Ravi, KUNWAR, A. C.

“…We describe for the first time the free radical cyclization of enantiomerically pure alkyne-tethered aldehydes obtained from a carbohydrate (6, 7). The…”
Get full text

Asymmetric Synthesis of (+)-a llo-Quercitol and (+)-t alo-Quercitol via Free Radical Cycloisomerization of an Enantiomerically Pure Alkyne-Tethered Aldehyde Derived from a Carbohydrate by Yadav, J. S, Maiti, Arup, Sankar, A. Ravi, Kunwar, A. C

“…We describe for the first time the free radical cyclization of enantiomerically pure alkyne-tethered aldehydes obtained from a carbohydrate (6, 7). The…”
Get full text

ONE-POT OXIDATION AND WITTIG OLEFINATION OF ALCOHOLS USING O-IODOXYBENZOIC ACID AND STABLE WITTIG YLIDE by Maiti, Arup, Yadav, J. S.

“…Benylic, allylic, and propargylic alcohols, as well as diols, can be oxidized with o-iodoxybenzoic acid (IBX) in the presence of stabilized Wittig ylide [1] to…”
Get full text